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The map label for this gene is dsbC [H]

Identifier: 17547611

GI number: 17547611

Start: 3120920

End: 3121666

Strand: Reverse

Name: dsbC [H]

Synonym: RSc2892

Alternate gene names: 17547611

Gene position: 3121666-3120920 (Counterclockwise)

Preceding gene: 17547612

Following gene: 17547610

Centisome position: 84.0

GC content: 65.46

Gene sequence:

>747_bases
ATGTCGTTTCGTATTCGGGTGGCGGCCATCGCCTCGGCGGCGCTGGTTGTCGCCATGGGCGCGGGCTACGCGCTGACCGC
CGGTGCCGCCGAGCCCGCGCTGGACAAGGTCAAGGCCTCGGTGCAGAAGGCGCTGGGATCGAACGTCGAGATCAAGGGCG
TGGCCAAGTCGCCGCTGCCGGGGCTGTACGAGGTGAATCTCGGCAGTCAGGTCGTCTACACGGATGCCACCGGCCGCTAT
GTGCTCAACGGCGACCTGCTCGATACGCAGACTGCGACCAACCTCACGCAGGAGCGCATGGCCGAGATCAACCGCATCAA
GTGGTCCGACCTGCCGCTGGATCGCGCGGTGAAGTGGGTCAAGGGCAACGGCGCGCGCAAGGTTGCCGTGTTCTCCGACC
CGAACTGCCCGTACTGCCACAAGCTGGAGCAGATGTTCTCGCAGGTCGACAACATCACGGTCTACACCTTCCTGTTCCCG
ATCCTGTCCGAGGACTCCAACACCAAGGCCAAGCAGATCTGGTGCGCGTCTGACCGTGCCAAGGCCTGGCGCGACTGGAT
GGTGTCCAAGAGCGCCCCGGGCGGTGCCGGCAATTGCGACACGCCGCTGGAAGACAACCTCAAGCTGGGCCGCGCGCTCA
ACGTCAACGGCACCCCGGCCATCATCTTCATGGACGGCTCGCGGGCGCCGGGCCTGATCGATGCGGCCACGCTGGAACGC
AAGTTCGCGTCGCTGAAGAAGTCGTGA

Upstream 100 bases:

>100_bases
GGGCATGCGCGTGGTGGGCCTGACGCCATTCATCAAACGCCTGCTGGTCAGGCACGCGCTAGGCTAGCCGTCCGTCGGCA
GCCGGCTTCCAGGAGTTGTC

Downstream 100 bases:

>100_bases
TCCAGAGCGCCGGTTGCACCCGGCGCTTTTTTCTTTGCCCGCCGCCACCCGGAGGCCGCCCATGTCGTTTCGCGCGCTGA
TGCTGGAAAAACAGGAAGGC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFRIRVAAIASAALVVAMGAGYALTAGAAEPALDKVKASVQKALGSNVEIKGVAKSPLPGLYEVNLGSQVVYTDATGRY
VLNGDLLDTQTATNLTQERMAEINRIKWSDLPLDRAVKWVKGNGARKVAVFSDPNCPYCHKLEQMFSQVDNITVYTFLFP
ILSEDSNTKAKQIWCASDRAKAWRDWMVSKSAPGGAGNCDTPLEDNLKLGRALNVNGTPAIIFMDGSRAPGLIDAATLER
KFASLKKS

Sequences:

>Translated_248_residues
MSFRIRVAAIASAALVVAMGAGYALTAGAAEPALDKVKASVQKALGSNVEIKGVAKSPLPGLYEVNLGSQVVYTDATGRY
VLNGDLLDTQTATNLTQERMAEINRIKWSDLPLDRAVKWVKGNGARKVAVFSDPNCPYCHKLEQMFSQVDNITVYTFLFP
ILSEDSNTKAKQIWCASDRAKAWRDWMVSKSAPGGAGNCDTPLEDNLKLGRALNVNGTPAIIFMDGSRAPGLIDAATLER
KFASLKKS
>Mature_247_residues
SFRIRVAAIASAALVVAMGAGYALTAGAAEPALDKVKASVQKALGSNVEIKGVAKSPLPGLYEVNLGSQVVYTDATGRYV
LNGDLLDTQTATNLTQERMAEINRIKWSDLPLDRAVKWVKGNGARKVAVFSDPNCPYCHKLEQMFSQVDNITVYTFLFPI
LSEDSNTKAKQIWCASDRAKAWRDWMVSKSAPGGAGNCDTPLEDNLKLGRALNVNGTPAIIFMDGSRAPGLIDAATLERK
FASLKKS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=202, Percent_Identity=29.2079207920792, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26712; Mature: 26581

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRIRVAAIASAALVVAMGAGYALTAGAAEPALDKVKASVQKALGSNVEIKGVAKSPLP
CCEEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GLYEVNLGSQVVYTDATGRYVLNGDLLDTQTATNLTQERMAEINRIKWSDLPLDRAVKWV
CEEEECCCCEEEEECCCCCEEEECCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGNGARKVAVFSDPNCPYCHKLEQMFSQVDNITVYTFLFPILSEDSNTKAKQIWCASDRA
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCHHEEEECCCHH
KAWRDWMVSKSAPGGAGNCDTPLEDNLKLGRALNVNGTPAIIFMDGSRAPGLIDAATLER
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHH
KFASLKKS
HHHHHCCC
>Mature Secondary Structure 
SFRIRVAAIASAALVVAMGAGYALTAGAAEPALDKVKASVQKALGSNVEIKGVAKSPLP
CEEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
GLYEVNLGSQVVYTDATGRYVLNGDLLDTQTATNLTQERMAEINRIKWSDLPLDRAVKWV
CEEEECCCCEEEEECCCCCEEEECCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGNGARKVAVFSDPNCPYCHKLEQMFSQVDNITVYTFLFPILSEDSNTKAKQIWCASDRA
CCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCHHEEEECCCHH
KAWRDWMVSKSAPGGAGNCDTPLEDNLKLGRALNVNGTPAIIFMDGSRAPGLIDAATLER
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHH
KFASLKKS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]