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The map label for this gene is fruR [H]

Identifier: 17547579

GI number: 17547579

Start: 3080376

End: 3081365

Strand: Reverse

Name: fruR [H]

Synonym: RSc2860

Alternate gene names: 17547579

Gene position: 3081365-3080376 (Counterclockwise)

Preceding gene: 17547584

Following gene: 17547578

Centisome position: 82.91

GC content: 73.23

Gene sequence:

>990_bases
ATGACGGTCCGGATCAAGGATGTCGCGGCGGCGGCCGGGGTGTCGGTGGCAACGGTGTCGCGCGCGCTGGCCGGCGGGCC
GGTCAGCGAGGCGCTGCGCAAGCGTGTCGATGCCGCGGTGGCGGCGTCGGGCTATCGGCCCAACCTGTCGGCGCGGCGGC
TGCGCTCGCAGCAGGCGCAGACCGTCGGGCTGATCGTGTCGGACATCCGCAACCCGTTCTTCACCAGCGTCAGCCGGGCG
GTGGAGGACGCCGCCTACGCGGCCGGCCTGCGCGTGATCTTGTGCAATTCCGACGAGGATCCCGACAAGGAAGCGATGTA
CCTGCGCCTGATGGAGGAGGAGCGCGTGACCGGCGTGATCCTGTCGCCCACGCGCCGCATCGCCGAATCGCCGGCGCCGG
TGGTGCTCGGGTTCCCGGTGGTGCTGATTGACCGCGCCGGCCCGGCCTGCGGCGTCGACGCCGTGGTGCTCGACAACCAG
CAGGCGGCGCAGGCGCTGGCCGAGCATCTGGCGCAGCACGGCTACCGGCGCATCGGCGGGCTGTTCGGCCGCACCAGCAG
CACCGGCGCGGAGCGACACGCGGGCGTGGCCGCCGGGCTGGCCCGCCACGGCCTGGCGATCGATGCGCGCTTCATCCTGC
CCACCGCCGAGGCCGCCGAAGCCGAAACGCTGGCATGGCTGGCCTCGGGCGAGCGGCCCGACGCGCTGGTCGCCAGCAAT
GCGCAGTCGCTGCTGGGCGTGCTGCGGGCGATCCGCCGTCTGTCGCTGGACGTGCCGGGCGACATCGCCGTGGCCGGTTT
CGACAACGAGCCGTGGACGGAGCTGGCCGGACCGGGCGTCACCGTGATCGAACAGCCGGTCTACGACATCGGGCGCCTGG
CGATGACGATGCTGCAGGAGCGGCTGGCGCAACCCGAATTGCCCACGCGCCGGGTGCTGCTGACGGGGCGGCTGGTGGCG
CGCGGCTCGACGCCGCAGCGACGCATGTAG

Upstream 100 bases:

>100_bases
ATAGTTGTGCTCAATGTTGGGGAATTCCCGAGTGTGGCGGCCGTTGGTTGCCGTGTCGGCATTCGCTATCATGGCGCTTT
CTTTGGAAACGATTTCAGCG

Downstream 100 bases:

>100_bases
CGGGCGATTACAATGCCCGGACGAAGACGGCACCGCCCGCCGCCCCACTCCGGAGCTCCCGATGTCCACCCAAGTCATCC
GTGCCGCGTGTCCGCACGAC

Product: transcription regulation repressor transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTVRIKDVAAAAGVSVATVSRALAGGPVSEALRKRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRA
VEDAAYAAGLRVILCNSDEDPDKEAMYLRLMEEERVTGVILSPTRRIAESPAPVVLGFPVVLIDRAGPACGVDAVVLDNQ
QAAQALAEHLAQHGYRRIGGLFGRTSSTGAERHAGVAAGLARHGLAIDARFILPTAEAAEAETLAWLASGERPDALVASN
AQSLLGVLRAIRRLSLDVPGDIAVAGFDNEPWTELAGPGVTVIEQPVYDIGRLAMTMLQERLAQPELPTRRVLLTGRLVA
RGSTPQRRM

Sequences:

>Translated_329_residues
MTVRIKDVAAAAGVSVATVSRALAGGPVSEALRKRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRA
VEDAAYAAGLRVILCNSDEDPDKEAMYLRLMEEERVTGVILSPTRRIAESPAPVVLGFPVVLIDRAGPACGVDAVVLDNQ
QAAQALAEHLAQHGYRRIGGLFGRTSSTGAERHAGVAAGLARHGLAIDARFILPTAEAAEAETLAWLASGERPDALVASN
AQSLLGVLRAIRRLSLDVPGDIAVAGFDNEPWTELAGPGVTVIEQPVYDIGRLAMTMLQERLAQPELPTRRVLLTGRLVA
RGSTPQRRM
>Mature_328_residues
TVRIKDVAAAAGVSVATVSRALAGGPVSEALRKRVDAAVAASGYRPNLSARRLRSQQAQTVGLIVSDIRNPFFTSVSRAV
EDAAYAAGLRVILCNSDEDPDKEAMYLRLMEEERVTGVILSPTRRIAESPAPVVLGFPVVLIDRAGPACGVDAVVLDNQQ
AAQALAEHLAQHGYRRIGGLFGRTSSTGAERHAGVAAGLARHGLAIDARFILPTAEAAEAETLAWLASGERPDALVASNA
QSLLGVLRAIRRLSLDVPGDIAVAGFDNEPWTELAGPGVTVIEQPVYDIGRLAMTMLQERLAQPELPTRRVLLTGRLVAR
GSTPQRRM

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=336, Percent_Identity=32.7380952380952, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790369, Length=326, Percent_Identity=30.9815950920245, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789202, Length=289, Percent_Identity=32.5259515570934, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787906, Length=340, Percent_Identity=32.9411764705882, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789068, Length=339, Percent_Identity=28.6135693215339, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788474, Length=301, Percent_Identity=30.2325581395349, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=27.7945619335347, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI48994940, Length=303, Percent_Identity=27.0627062706271, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=26.8987341772152, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786268, Length=326, Percent_Identity=26.6871165644172, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786540, Length=330, Percent_Identity=28.1818181818182, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=23.7082066869301, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790689, Length=298, Percent_Identity=26.8456375838926, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789456, Length=337, Percent_Identity=23.7388724035608, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34888; Mature: 34757

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRIKDVAAAAGVSVATVSRALAGGPVSEALRKRVDAAVAASGYRPNLSARRLRSQQAQ
CEEEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TVGLIVSDIRNPFFTSVSRAVEDAAYAAGLRVILCNSDEDPDKEAMYLRLMEEERVTGVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
LSPTRRIAESPAPVVLGFPVVLIDRAGPACGVDAVVLDNQQAAQALAEHLAQHGYRRIGG
ECCHHHHHCCCCCEEEECCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LFGRTSSTGAERHAGVAAGLARHGLAIDARFILPTAEAAEAETLAWLASGERPDALVASN
HHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCC
AQSLLGVLRAIRRLSLDVPGDIAVAGFDNEPWTELAGPGVTVIEQPVYDIGRLAMTMLQE
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHH
RLAQPELPTRRVLLTGRLVARGSTPQRRM
HHCCCCCCCCEEEEECEEEECCCCCCCCC
>Mature Secondary Structure 
TVRIKDVAAAAGVSVATVSRALAGGPVSEALRKRVDAAVAASGYRPNLSARRLRSQQAQ
EEEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TVGLIVSDIRNPFFTSVSRAVEDAAYAAGLRVILCNSDEDPDKEAMYLRLMEEERVTGVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
LSPTRRIAESPAPVVLGFPVVLIDRAGPACGVDAVVLDNQQAAQALAEHLAQHGYRRIGG
ECCHHHHHCCCCCEEEECCEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LFGRTSSTGAERHAGVAAGLARHGLAIDARFILPTAEAAEAETLAWLASGERPDALVASN
HHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCC
AQSLLGVLRAIRRLSLDVPGDIAVAGFDNEPWTELAGPGVTVIEQPVYDIGRLAMTMLQE
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHH
RLAQPELPTRRVLLTGRLVARGSTPQRRM
HHCCCCCCCCEEEEECEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]