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The map label for this gene is argJ

Identifier: 17547552

GI number: 17547552

Start: 3045502

End: 3046731

Strand: Reverse

Name: argJ

Synonym: RSc2833

Alternate gene names: 17547552

Gene position: 3046731-3045502 (Counterclockwise)

Preceding gene: 17547553

Following gene: 17547551

Centisome position: 81.98

GC content: 68.94

Gene sequence:

>1230_bases
ATGGCTGTGAATCTCGTCGCGCCCGCCGCTGACTCCCTGTTGCCGATCGATGGCGTCGACCTCGGCTGGGCCGAAGCCGG
CATCCGCAAGGCCAATCGCAAGGACGTGCTGCTGGTGCGCATCGCCGAGGGGGCGAGCGTGGCGGGCGTGTTCACGCAGA
ACCGATTCTGCGCGGCACCGGTGCAGGTCTGCCGCGAGCACCTGGCCAGCGGGCAGGGCGCGCGCGCGATTGTCGTGAAC
ACCGGCAATGCGAACGCCGGCACCGGTGCGCCGGGCCTGGCGCTCGCGCGCCAGACCTGCGAGGCGGTGGCCGGGCTGCT
CGGGATTGCGCCGCAGCAGGTGCTGCCGTTCTCGACCGGCGTGATTCTCGAGCCGCTGCCGGTGGATCGCCTCATCGCCG
GGCTGCCCGCGGCGCAGGCCAATGCCAAGCCCGACAACTGGCTGGCGGCCGCCGAGTCCATCATGACCACCGACACCGTG
CCCAAGGCGGCATCGGGCACCTGCACGCTGTCGGGCAAGCCGGTGCGCCTGTCGGGCATCAGCAAGGGCGCGGGCATGAT
CCGCCCGAACATGGCGACCATGCTCGGCTTCATCGCCACCGATGCCAACGTGGATGAAGCCGTGCTGCAGGGCCTGGTGC
GCCATGCCGCCGACCATTCCTTCAACAGCGTGACGGTCGACGGCGATACGTCGACCAACGATTCCTTCGTCGTCATCGCC
ACGGGCCGTGCCGGTACGCCGCGCATCGATTCCGAATCGCACCCCGACTACGCCGCGCTGCGCGATGCGCTCACGGGCCT
GGCGCAGGCGCTGGCACAGAAGATCGTGCGCGACGGCGAAGGCGCGACCAAGTTTATGACCATCCGCGTCGAAGGCGGCC
GCAGCGTGGACGAATGCCGCCAGGTCGCTTATGCGGTCGCGCATTCGCCGCTGGTCAAGACCGCGTTCTATGCGTCGGAT
CCCAACCTGGGCCGCATCCTGGCCGCGGTCGGCTATGCGGGCGTGAACGATCTCGACGTGGACGGCGTCAACCTGTGGCT
CGACGATGTCTGGGTCGCCCGCGACGGCGGCCGCAATCCGGACTATCGCGAAGAAGACGGCCAGCGCGTGATGAAGCAGG
CCGAGATCACCGTCCGCATCGCGCTCGGCCGCGGCGACGCGACCGCCACGGTGTGGACGTGCGACTTCTCGCACGACTAC
GTCTCGATCAACGCGGATTACCGCTCGTAA

Upstream 100 bases:

>100_bases
CCGGCCGACTGCCGCGGGCGCCGCGCCGCGCGGCGCCGTTCGTTTCCTGTTGATTCAACGATGCCCGCATTGCGGGCATC
CTCGTTTGAAAAGGTGCTCC

Downstream 100 bases:

>100_bases
GCGACGACCGCCGCCATGTCTTCCGATCTCACCGTCCGGCTCGAGCGCTTCCTGGGCCGCCTCGAGCAATGGCTGCCGCC
CGAGCTGACCGAGGCCGACT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAVNLVAPAADSLLPIDGVDLGWAEAGIRKANRKDVLLVRIAEGASVAGVFTQNRFCAAPVQVCREHLASGQGARAIVVN
TGNANAGTGAPGLALARQTCEAVAGLLGIAPQQVLPFSTGVILEPLPVDRLIAGLPAAQANAKPDNWLAAAESIMTTDTV
PKAASGTCTLSGKPVRLSGISKGAGMIRPNMATMLGFIATDANVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
TGRAGTPRIDSESHPDYAALRDALTGLAQALAQKIVRDGEGATKFMTIRVEGGRSVDECRQVAYAVAHSPLVKTAFYASD
PNLGRILAAVGYAGVNDLDVDGVNLWLDDVWVARDGGRNPDYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDY
VSINADYRS

Sequences:

>Translated_409_residues
MAVNLVAPAADSLLPIDGVDLGWAEAGIRKANRKDVLLVRIAEGASVAGVFTQNRFCAAPVQVCREHLASGQGARAIVVN
TGNANAGTGAPGLALARQTCEAVAGLLGIAPQQVLPFSTGVILEPLPVDRLIAGLPAAQANAKPDNWLAAAESIMTTDTV
PKAASGTCTLSGKPVRLSGISKGAGMIRPNMATMLGFIATDANVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
TGRAGTPRIDSESHPDYAALRDALTGLAQALAQKIVRDGEGATKFMTIRVEGGRSVDECRQVAYAVAHSPLVKTAFYASD
PNLGRILAAVGYAGVNDLDVDGVNLWLDDVWVARDGGRNPDYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDY
VSINADYRS
>Mature_408_residues
AVNLVAPAADSLLPIDGVDLGWAEAGIRKANRKDVLLVRIAEGASVAGVFTQNRFCAAPVQVCREHLASGQGARAIVVNT
GNANAGTGAPGLALARQTCEAVAGLLGIAPQQVLPFSTGVILEPLPVDRLIAGLPAAQANAKPDNWLAAAESIMTTDTVP
KAASGTCTLSGKPVRLSGISKGAGMIRPNMATMLGFIATDANVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIAT
GRAGTPRIDSESHPDYAALRDALTGLAQALAQKIVRDGEGATKFMTIRVEGGRSVDECRQVAYAVAHSPLVKTAFYASDP
NLGRILAAVGYAGVNDLDVDGVNLWLDDVWVARDGGRNPDYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYV
SINADYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=413, Percent_Identity=38.498789346247, Blast_Score=269, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_RALSO (Q8XVJ7)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520954.1
- ProteinModelPortal:   Q8XVJ7
- SMR:   Q8XVJ7
- MEROPS:   T05.001
- GeneID:   1221681
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2833
- NMPDR:   fig|267608.1.peg.2833
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   RSOL267608:RSC2833-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42757; Mature: 42625

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNLVAPAADSLLPIDGVDLGWAEAGIRKANRKDVLLVRIAEGASVAGVFTQNRFCAAP
CEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEHHH
VQVCREHLASGQGARAIVVNTGNANAGTGAPGLALARQTCEAVAGLLGIAPQQVLPFSTG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCC
VILEPLPVDRLIAGLPAAQANAKPDNWLAAAESIMTTDTVPKAASGTCTLSGKPVRLSGI
CEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECC
SKGAGMIRPNMATMLGFIATDANVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGRAGTPRIDSESHPDYAALRDALTGLAQALAQKIVRDGEGATKFMTIRVEGGRSVDECR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
QVAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVNDLDVDGVNLWLDDVWVARDGGRNP
HHHHHHHCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCC
DYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYVSINADYRS
CCCCHHHHHHHHHCEEEEEEEECCCCCEEEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure 
AVNLVAPAADSLLPIDGVDLGWAEAGIRKANRKDVLLVRIAEGASVAGVFTQNRFCAAP
EEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEHHH
VQVCREHLASGQGARAIVVNTGNANAGTGAPGLALARQTCEAVAGLLGIAPQQVLPFSTG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCC
VILEPLPVDRLIAGLPAAQANAKPDNWLAAAESIMTTDTVPKAASGTCTLSGKPVRLSGI
CEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECC
SKGAGMIRPNMATMLGFIATDANVDEAVLQGLVRHAADHSFNSVTVDGDTSTNDSFVVIA
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEE
TGRAGTPRIDSESHPDYAALRDALTGLAQALAQKIVRDGEGATKFMTIRVEGGRSVDECR
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
QVAYAVAHSPLVKTAFYASDPNLGRILAAVGYAGVNDLDVDGVNLWLDDVWVARDGGRNP
HHHHHHHCCCHHHEEEECCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCC
DYREEDGQRVMKQAEITVRIALGRGDATATVWTCDFSHDYVSINADYRS
CCCCHHHHHHHHHCEEEEEEEECCCCCEEEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852