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The map label for this gene is pilC [H]

Identifier: 17547545

GI number: 17547545

Start: 3040292

End: 3041557

Strand: Direct

Name: pilC [H]

Synonym: RSc2826

Alternate gene names: 17547545

Gene position: 3040292-3041557 (Clockwise)

Preceding gene: 17547544

Following gene: 17547546

Centisome position: 81.81

GC content: 62.32

Gene sequence:

>1266_bases
ATGGCCACACGAGCACCGACCGCGAACCGGTCCGCCGCCGCATCGGCACGCAAGACCGCCGCCACGAAGGCGCCCACGCA
GTACATCTTCGAGTGGGAAGGCAAGGACCGCAAAGGCAAGATCTTCAAGGGCGAGATGCGGGCGGAGAGCATCACCGAAG
TCAATGCGGTGCTGCGCAAGCAAGGGCTGTCGATCACCAAGTCCAAGCGTCGACGCGCCGCGCGCGGCAAGAAGATCGTA
CCCAAGGACATCGCCTACTTCACGCGCCAGCTGTCGACCATGCTGAAAGCGGGCGTGCCGCTGCTGCAATCGGTCGACAT
CATCGCGCGCGGGCACGCCAACCCGAACTTCACCCAGCTGCTGACGGAAATCCGTGTCGACATCGAGTCGGGCAGCAGCA
TGGCGCAGGCCTTCCGCCGCCATCCGCAGCACTTCGATTCGCTGTACTGCAACCTGATCGACGCCGGTGAGCAGGGCGGT
ATTCTCGACGCGCTGCTCGAGCGGCTGTCGATGTACATGGAAAAGTCGATCGCGCTGAAGGCGCAGATCAAGTCGGCCAT
GATCTATCCGATCTCGGTGCTGACGGTGGCTTTCCTGGTCACGGTGGTGCTGATGATCTTCGTGGTGCCGGCGTTCAAGA
ACGTGTTCGCCAGCTTCGGCGCCACGCTGCCGGCCCCGACGCTGGTGGTGATGGGCATTTCGGACTTCTTCGTGAAGTGG
TGGTACATCATCATCTTCACGCCCATTGTCGGCATCTTCCTGTATGTGCGGGCTTTCAAGCGCTCGGAGAAGGTGCAGCG
CAACACGCACAAGGCCATCCTGAAGATGCCGATCTTCGGCAGCATCATCCGCAAGGCCACCATCGCGCGCTGGACGCGTA
CGCTGGCAACCATGTTCTCGGCCGGGACACCGCTGGTGGAGTCGATGGAATCCGTCGCGGGCGCCGCCGGCAACTGGGTC
TACTATGACGCCACCATGGAGATCCAGCAGGCGGTGCGCATCGGTACCAGCCTCACCAACGCCATGCAGGCGACCCATGT
GTTCGACAACATGGTGCTGCAGATGACGCAGATCGGCGAGGAATCCGGCGCGCTGGACAACATGCTGCTGAAGGTGGCCG
AATTCTACGAGCGCGAGGTCGATGACGCGGTGGCCAACATCTCCGCCCTGATCGAGCCGCTCATCATCGTGATCCTGGGC
GTGCTGATCGGGGGCATGGTGGTTGCCATGTACCTGCCGATCTTCAAGCTGGGCCAAGTGGTCTGA

Upstream 100 bases:

>100_bases
AAGTGAAGCAGGGGCTGACTTCCCTTGAGGAAGTGTTGGCCACGACCAACCAGTAACCTTCTCGATCAATCGTTCCCATA
CCGGGGGGTAGGAACCAAAC

Downstream 100 bases:

>100_bases
TGATGCCCGGAATGTTCGTCATTCCCACGCTGGCGCAACTGCCGGCGTGGTTCGTGATCGGCGCGGGGACGCTGCTGGGC
TTGCTGGTCGGCAGCTTCCT

Product: fimbrial assembly transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MATRAPTANRSAAASARKTAATKAPTQYIFEWEGKDRKGKIFKGEMRAESITEVNAVLRKQGLSITKSKRRRAARGKKIV
PKDIAYFTRQLSTMLKAGVPLLQSVDIIARGHANPNFTQLLTEIRVDIESGSSMAQAFRRHPQHFDSLYCNLIDAGEQGG
ILDALLERLSMYMEKSIALKAQIKSAMIYPISVLTVAFLVTVVLMIFVVPAFKNVFASFGATLPAPTLVVMGISDFFVKW
WYIIIFTPIVGIFLYVRAFKRSEKVQRNTHKAILKMPIFGSIIRKATIARWTRTLATMFSAGTPLVESMESVAGAAGNWV
YYDATMEIQQAVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLLKVAEFYEREVDDAVANISALIEPLIIVILG
VLIGGMVVAMYLPIFKLGQVV

Sequences:

>Translated_421_residues
MATRAPTANRSAAASARKTAATKAPTQYIFEWEGKDRKGKIFKGEMRAESITEVNAVLRKQGLSITKSKRRRAARGKKIV
PKDIAYFTRQLSTMLKAGVPLLQSVDIIARGHANPNFTQLLTEIRVDIESGSSMAQAFRRHPQHFDSLYCNLIDAGEQGG
ILDALLERLSMYMEKSIALKAQIKSAMIYPISVLTVAFLVTVVLMIFVVPAFKNVFASFGATLPAPTLVVMGISDFFVKW
WYIIIFTPIVGIFLYVRAFKRSEKVQRNTHKAILKMPIFGSIIRKATIARWTRTLATMFSAGTPLVESMESVAGAAGNWV
YYDATMEIQQAVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLLKVAEFYEREVDDAVANISALIEPLIIVILG
VLIGGMVVAMYLPIFKLGQVV
>Mature_420_residues
ATRAPTANRSAAASARKTAATKAPTQYIFEWEGKDRKGKIFKGEMRAESITEVNAVLRKQGLSITKSKRRRAARGKKIVP
KDIAYFTRQLSTMLKAGVPLLQSVDIIARGHANPNFTQLLTEIRVDIESGSSMAQAFRRHPQHFDSLYCNLIDAGEQGGI
LDALLERLSMYMEKSIALKAQIKSAMIYPISVLTVAFLVTVVLMIFVVPAFKNVFASFGATLPAPTLVVMGISDFFVKWW
YIIIFTPIVGIFLYVRAFKRSEKVQRNTHKAILKMPIFGSIIRKATIARWTRTLATMFSAGTPLVESMESVAGAAGNWVY
YDATMEIQQAVRIGTSLTNAMQATHVFDNMVLQMTQIGEESGALDNMLLKVAEFYEREVDDAVANISALIEPLIIVILGV
LIGGMVVAMYLPIFKLGQVV

Specific function: Involved in the translocation of the type IV pilin [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=26.8170426065163, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786295, Length=394, Percent_Identity=30.4568527918782, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 46571; Mature: 46439

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRAPTANRSAAASARKTAATKAPTQYIFEWEGKDRKGKIFKGEMRAESITEVNAVLRK
CCCCCCCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCCCEEECHHHHHHHHHHHHHHHH
QGLSITKSKRRRAARGKKIVPKDIAYFTRQLSTMLKAGVPLLQSVDIIARGHANPNFTQL
HCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHH
LTEIRVDIESGSSMAQAFRRHPQHFDSLYCNLIDAGEQGGILDALLERLSMYMEKSIALK
HHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQIKSAMIYPISVLTVAFLVTVVLMIFVVPAFKNVFASFGATLPAPTLVVMGISDFFVKW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHH
WYIIIFTPIVGIFLYVRAFKRSEKVQRNTHKAILKMPIFGSIIRKATIARWTRTLATMFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGTPLVESMESVAGAAGNWVYYDATMEIQQAVRIGTSLTNAMQATHVFDNMVLQMTQIGE
CCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ESGALDNMLLKVAEFYEREVDDAVANISALIEPLIIVILGVLIGGMVVAMYLPIFKLGQV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
V
C
>Mature Secondary Structure 
ATRAPTANRSAAASARKTAATKAPTQYIFEWEGKDRKGKIFKGEMRAESITEVNAVLRK
CCCCCCCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCCCEEECHHHHHHHHHHHHHHHH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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8820654 [H]