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The map label for this gene is ubiC

Identifier: 17547499

GI number: 17547499

Start: 2991817

End: 2992347

Strand: Reverse

Name: ubiC

Synonym: RSc2780

Alternate gene names: 17547499

Gene position: 2992347-2991817 (Counterclockwise)

Preceding gene: 17547500

Following gene: 17547498

Centisome position: 80.52

GC content: 71.75

Gene sequence:

>531_bases
ATGGCCGTGTATGGCCAGCATTGGGCGCGCTGGGCGGTCGGCGTGAATTCACTGACGGCACGGCTGCGTGCGGCATCGTC
TTCGTTTCGTGTCGAACTGCTCGGCCAGGGGCGAGCCCTGCCGCTGCGCGACGAGTGGCGGTGCCTGGGCTTGCCCCGCG
CCGCCGAGACGCTGGCGCGCGAGGTGCTGCTGATCTGCGACGAGGCGCCGGTGGTCTACGCGCATACGATCGTGCATCCG
CGCAGCGTGGCGGCGGACTGGCCGTTCCTGAGGGCGCTCGGCACTCAGCCGCTCGGGCATGCGCTGTTCGCCGACCCGCG
CGTTGCCCGGGGGGCCTTCGAATTCGCCCTGCTGGATGGCCGGCATCCGCTGGTCAAACGGGCCCACGCAGCGCTGGGCG
GCACGCCGCCGGGCGCCATGGCGCGGCTGCCGGCGCGCCGTTCAGTGTTCCGCCGCGGCGTTAGCGCGATGCTGGTGACG
GAAGTGTTCTTGCCGGCACTGGCGGTGTTCGACCCGCCGCCCATGATGTGA

Upstream 100 bases:

>100_bases
CCGGATTATTGGCCGCCCATCCTTTCGACCGCCAGGCCGGCGCATGAGCGGGGCCGCCATGTCGTACCCGCGCAGTCCGT
GGCGCGGGGCCTTGCCGCCC

Downstream 100 bases:

>100_bases
TGCGGGCGATCGGGCGGGCCGGATGGCCGTCCGGTGCGGTATCATCGCCCCCGTCTTTTGTCGTTGCGGCGCAGGCCGGT
TCCATCCGGGGCGCGCGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MAVYGQHWARWAVGVNSLTARLRAASSSFRVELLGQGRALPLRDEWRCLGLPRAAETLAREVLLICDEAPVVYAHTIVHP
RSVAADWPFLRALGTQPLGHALFADPRVARGAFEFALLDGRHPLVKRAHAALGGTPPGAMARLPARRSVFRRGVSAMLVT
EVFLPALAVFDPPPMM

Sequences:

>Translated_176_residues
MAVYGQHWARWAVGVNSLTARLRAASSSFRVELLGQGRALPLRDEWRCLGLPRAAETLAREVLLICDEAPVVYAHTIVHP
RSVAADWPFLRALGTQPLGHALFADPRVARGAFEFALLDGRHPLVKRAHAALGGTPPGAMARLPARRSVFRRGVSAMLVT
EVFLPALAVFDPPPMM
>Mature_175_residues
AVYGQHWARWAVGVNSLTARLRAASSSFRVELLGQGRALPLRDEWRCLGLPRAAETLAREVLLICDEAPVVYAHTIVHPR
SVAADWPFLRALGTQPLGHALFADPRVARGAFEFALLDGRHPLVKRAHAALGGTPPGAMARLPARRSVFRRGVSAMLVTE
VFLPALAVFDPPPMM

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_RALSO (Q8XVQ0)

Other databases:

- EMBL:   AL646052
- ProteinModelPortal:   Q8XVQ0
- SMR:   Q8XVQ0
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2780
- NMPDR:   fig|267608.1.peg.2780
- HOGENOM:   HBG644467
- OMA:   MNTSSGW
- ProtClustDB:   CLSK2302719
- BioCyc:   RSOL267608:RSC2780-MONOMER
- BRENDA:   4.1.3.40
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19188; Mature: 19056

Theoretical pI: Translated: 11.59; Mature: 11.59

Prosite motif: NA

Important sites: BINDING 79-79 BINDING 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYGQHWARWAVGVNSLTARLRAASSSFRVELLGQGRALPLRDEWRCLGLPRAAETLAR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHH
EVLLICDEAPVVYAHTIVHPRSVAADWPFLRALGTQPLGHALFADPRVARGAFEFALLDG
HHHHHCCCCCEEEEEEEECCHHHCCCCHHHHHHCCCCCCHHHHCCCHHHHHHEEEEEECC
RHPLVKRAHAALGGTPPGAMARLPARRSVFRRGVSAMLVTEVFLPALAVFDPPPMM
CCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVYGQHWARWAVGVNSLTARLRAASSSFRVELLGQGRALPLRDEWRCLGLPRAAETLAR
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHH
EVLLICDEAPVVYAHTIVHPRSVAADWPFLRALGTQPLGHALFADPRVARGAFEFALLDG
HHHHHCCCCCEEEEEEEECCHHHCCCCHHHHHHCCCCCCHHHHCCCHHHHHHEEEEEECC
RHPLVKRAHAALGGTPPGAMARLPARRSVFRRGVSAMLVTEVFLPALAVFDPPPMM
CCHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852