Click here to switch to the map view.

The map label for this gene is fhuA [H]

Identifier: 17547448

GI number: 17547448

Start: 2935826

End: 2937895

Strand: Reverse

Name: fhuA [H]

Synonym: RSc2729

Alternate gene names: 17547448

Gene position: 2937895-2935826 (Counterclockwise)

Preceding gene: 17547458

Following gene: 17547447

Centisome position: 79.05

GC content: 70.43

Gene sequence:

>2070_bases
ATGGCATTGTTCGGCGCACCCGAACCGGCCGCCGCAGACGATGTTCCGACGCTGGCGCTGGAGGAGGCCGTCGTCCGCGC
GCAGGCGGGCGAGCGCTTGCGGGCCCGGCGCGCAACTTCCGCCACGCTGACCGACACGCCGCTCAAGGACGTGCCGCAGT
CCGTCGGCGTGGTCACGCGCGCGGCGCTGGACGGCTTCGGCGCGACGCGGCTGGACACGGCGCTCGACTGGGTCAGCGGC
ATCAGCCGGCAGAACAACCTGGGCGGCATCGCCGACAACTTCGCCATCCGCGGCTTTGCCGGCGACCTGAACACGGGCTC
GGACTACCTCGTCAACGGTTTTTCGGCCAACCGCGCCAACAGCGTGCCGGTGGACACCATCAACATCGCGCGCATCGACG
TGCTGAAGGGGCCGTCGGCGGCGCTTTACGGGCGCAGCGATCCGGGCGGCATCGTCAACATCGTCACGCGCACGCCGCAG
TTCAAGCCGTCGCGCGAGATCACGCTGGCGGCGGGCAGCCACGACCAGTACCGGCTGGCGACCGAACTGACCGGGCCGCT
GTCCGGGCACTTCGCCTACCGGCTGGGCCTGGCAGCGGAGAACAATCACGGCTTCCGGGAGTTTTCCGCCAGCCGGCGCT
ATGTGATTGCGCCATCGTTCACGTGGCTGCCCACCGACGACACCGTGGTGACCTATGCCTTCGAGGCGGCGCAGCTCAGG
GCACCGTTCGACCGGGGCATCGTGGCGATCAACCGGCAGTTGGGGGCGTTGCCCGATTCGCGCTTCCTGGGCGAGCCGGG
CGACGGCGATACCACGGTGCGCACGCAGAGCCACCAGCTGAGCGTCGAACACCAACTGGGCAGCGGCTGGAAAGTGGACG
CCGGGCTGTCGTACCGCACCTCGCGCCTGTTCGGCAAATCGTCCGATGCGTCGCGGCTGCTCGACGATGGCCGCACGCTG
TGGCGGCAGGCGCGCGAGCGCGACTACCACGCCAACGATCTGGCCGGCCGCGTCGACCTGCAGGGCGAGGTGGCCACCGG
ACCCGTCAGGCACACGCTGGTGGCCGGCGCCGACTTCTACAACTTCCGCTACGACCCGGTGCTGTACCGCGCCAACCCGA
GCGCATCGGCGCCGTATGCGATCGACATCTTCGATCCCGTGTACGGCCAGCCGCGGCCCGCGCTGCGGCCGAGCAGCAGC
ACGCGCGAGTCCCAGCGCGGCTTCGGCGCCTTCGTGCAGGACCAGGTCACGCTGACGCCGCAGTGGAAACTGCTGGCCGG
CGTGCGCATGGACCGCTTCCTGCAGCACGCCGACAACCGCCTGACCGGCGCGCGCGTCGCGCAGCAGCAGACCGCCTACA
GTCCGCGCCTGGGGCTGGTCTACCAGCCGACGCAGACCCTGTCGCTGTACGCCAATACCGCGCGCTCGTTCCGGCCCAAC
ACCGGGGTGGGGGCGCAGGGCAATGCGTTCGCGCCGGAGCGCGGGCGCGGCTACGAGGTCGGCGCCAAGCTGGAGACGGC
CGACGGCCGGTTCGGCGGCACGCTGGCGCTGTATTCGATCGACAAGACCAACGTGCTGACCGGCGATTCGCGCGATCCGG
TGTTCCAGCGCACCGCCGGCGCGGTGCGCAGCCGGGGCGTCGAGCTCGATGTGTCCGGCCAGCTGACGCCGAACCTCAAG
GTGCTGGGCACCTACGCCTATACCGACGCCCGTGTGACGGCGGACACCGTGCTGCCGTCGGGCGCGCCGCTGTCCAACAT
CCCGCGCCACAGCGCCAGCGCGCTGGGCCTGTATGAATTCGGCGCGGGATCGCTGGGCCGGGCGGGCGTGGGTGGCGGCG
TGGTCTACGTCGGCGAGCGCGCCGGCAACAGCACCGATAACGGCTTCAAGCTGCCGGCCTACGCCACCGTCCGCCTGAAC
GGCTACGTGCAGCCGACGCGCGCGCTGCGCCTGTCGCTGACCATCGACAACCTGTTCGACAAGCGCTACTACGCCAGTTC
GTACAACGAGCTGTGGGTCGCGCCCGGCGCCGAGCGGCAAGTCACGCTGGCGGCCACCTACACATTTTGA

Upstream 100 bases:

>100_bases
TTGCAAATTAACTAAGGTGAGCGCTTTCCGTCACTCGGTGGATGCTATGCAGCGTAGGCGGTATGCGGTCCGTCCGCATC
TCGGATGGGGCCTGGTGGGG

Downstream 100 bases:

>100_bases
GCATGACGCAATCCGGTTCCCGTGTTGTCGCCGTCGACTTGCTGCGCGGCCTGGTGATGGTGCTGATGGTGATCGACCAC
TTGCGCGAATTCTTCTTTCT

Product: ferrichrome-iron receptor protein

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MALFGAPEPAAADDVPTLALEEAVVRAQAGERLRARRATSATLTDTPLKDVPQSVGVVTRAALDGFGATRLDTALDWVSG
ISRQNNLGGIADNFAIRGFAGDLNTGSDYLVNGFSANRANSVPVDTINIARIDVLKGPSAALYGRSDPGGIVNIVTRTPQ
FKPSREITLAAGSHDQYRLATELTGPLSGHFAYRLGLAAENNHGFREFSASRRYVIAPSFTWLPTDDTVVTYAFEAAQLR
APFDRGIVAINRQLGALPDSRFLGEPGDGDTTVRTQSHQLSVEHQLGSGWKVDAGLSYRTSRLFGKSSDASRLLDDGRTL
WRQARERDYHANDLAGRVDLQGEVATGPVRHTLVAGADFYNFRYDPVLYRANPSASAPYAIDIFDPVYGQPRPALRPSSS
TRESQRGFGAFVQDQVTLTPQWKLLAGVRMDRFLQHADNRLTGARVAQQQTAYSPRLGLVYQPTQTLSLYANTARSFRPN
TGVGAQGNAFAPERGRGYEVGAKLETADGRFGGTLALYSIDKTNVLTGDSRDPVFQRTAGAVRSRGVELDVSGQLTPNLK
VLGTYAYTDARVTADTVLPSGAPLSNIPRHSASALGLYEFGAGSLGRAGVGGGVVYVGERAGNSTDNGFKLPAYATVRLN
GYVQPTRALRLSLTIDNLFDKRYYASSYNELWVAPGAERQVTLAATYTF

Sequences:

>Translated_689_residues
MALFGAPEPAAADDVPTLALEEAVVRAQAGERLRARRATSATLTDTPLKDVPQSVGVVTRAALDGFGATRLDTALDWVSG
ISRQNNLGGIADNFAIRGFAGDLNTGSDYLVNGFSANRANSVPVDTINIARIDVLKGPSAALYGRSDPGGIVNIVTRTPQ
FKPSREITLAAGSHDQYRLATELTGPLSGHFAYRLGLAAENNHGFREFSASRRYVIAPSFTWLPTDDTVVTYAFEAAQLR
APFDRGIVAINRQLGALPDSRFLGEPGDGDTTVRTQSHQLSVEHQLGSGWKVDAGLSYRTSRLFGKSSDASRLLDDGRTL
WRQARERDYHANDLAGRVDLQGEVATGPVRHTLVAGADFYNFRYDPVLYRANPSASAPYAIDIFDPVYGQPRPALRPSSS
TRESQRGFGAFVQDQVTLTPQWKLLAGVRMDRFLQHADNRLTGARVAQQQTAYSPRLGLVYQPTQTLSLYANTARSFRPN
TGVGAQGNAFAPERGRGYEVGAKLETADGRFGGTLALYSIDKTNVLTGDSRDPVFQRTAGAVRSRGVELDVSGQLTPNLK
VLGTYAYTDARVTADTVLPSGAPLSNIPRHSASALGLYEFGAGSLGRAGVGGGVVYVGERAGNSTDNGFKLPAYATVRLN
GYVQPTRALRLSLTIDNLFDKRYYASSYNELWVAPGAERQVTLAATYTF
>Mature_688_residues
ALFGAPEPAAADDVPTLALEEAVVRAQAGERLRARRATSATLTDTPLKDVPQSVGVVTRAALDGFGATRLDTALDWVSGI
SRQNNLGGIADNFAIRGFAGDLNTGSDYLVNGFSANRANSVPVDTINIARIDVLKGPSAALYGRSDPGGIVNIVTRTPQF
KPSREITLAAGSHDQYRLATELTGPLSGHFAYRLGLAAENNHGFREFSASRRYVIAPSFTWLPTDDTVVTYAFEAAQLRA
PFDRGIVAINRQLGALPDSRFLGEPGDGDTTVRTQSHQLSVEHQLGSGWKVDAGLSYRTSRLFGKSSDASRLLDDGRTLW
RQARERDYHANDLAGRVDLQGEVATGPVRHTLVAGADFYNFRYDPVLYRANPSASAPYAIDIFDPVYGQPRPALRPSSST
RESQRGFGAFVQDQVTLTPQWKLLAGVRMDRFLQHADNRLTGARVAQQQTAYSPRLGLVYQPTQTLSLYANTARSFRPNT
GVGAQGNAFAPERGRGYEVGAKLETADGRFGGTLALYSIDKTNVLTGDSRDPVFQRTAGAVRSRGVELDVSGQLTPNLKV
LGTYAYTDARVTADTVLPSGAPLSNIPRHSASALGLYEFGAGSLGRAGVGGGVVYVGERAGNSTDNGFKLPAYATVRLNG
YVQPTRALRLSLTIDNLFDKRYYASSYNELWVAPGAERQVTLAATYTF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=704, Percent_Identity=29.6875, Blast_Score=265, Evalue=8e-72,
Organism=Escherichia coli, GI1787024, Length=719, Percent_Identity=24.3393602225313, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1790743, Length=687, Percent_Identity=24.1630276564774, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787344, Length=288, Percent_Identity=26.0416666666667, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74215; Mature: 74083

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.1 %Met     (Mature Protein)
0.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFGAPEPAAADDVPTLALEEAVVRAQAGERLRARRATSATLTDTPLKDVPQSVGVVTR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AALDGFGATRLDTALDWVSGISRQNNLGGIADNFAIRGFAGDLNTGSDYLVNGFSANRAN
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC
SVPVDTINIARIDVLKGPSAALYGRSDPGGIVNIVTRTPQFKPSREITLAAGSHDQYRLA
CCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEE
TELTGPLSGHFAYRLGLAAENNHGFREFSASRRYVIAPSFTWLPTDDTVVTYAFEAAQLR
EECCCCCCCCEEEEEEEEECCCCCHHHHHCCCCEEEECCEEECCCCCCEEEEEEEHHHHC
APFDRGIVAINRQLGALPDSRFLGEPGDGDTTVRTQSHQLSVEHQLGSGWKVDAGLSYRT
CCHHCCEEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCEEEECCCCEEH
SRLFGKSSDASRLLDDGRTLWRQARERDYHANDLAGRVDLQGEVATGPVRHTLVAGADFY
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEE
NFRYDPVLYRANPSASAPYAIDIFDPVYGQPRPALRPSSSTRESQRGFGAFVQDQVTLTP
CEECCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCEEECC
QWKLLAGVRMDRFLQHADNRLTGARVAQQQTAYSPRLGLVYQPTQTLSLYANTARSFRPN
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHHCCCCC
TGVGAQGNAFAPERGRGYEVGAKLETADGRFGGTLALYSIDKTNVLTGDSRDPVFQRTAG
CCCCCCCCCCCCCCCCCEECCCEEECCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHH
AVRSRGVELDVSGQLTPNLKVLGTYAYTDARVTADTVLPSGAPLSNIPRHSASALGLYEF
HHHHCCEEEEECCCCCCCEEEEEEEEEECCEEEEHHCCCCCCCCCCCCCCCCCEEEEEEC
GAGSLGRAGVGGGVVYVGERAGNSTDNGFKLPAYATVRLNGYVQPTRALRLSLTIDNLFD
CCCCCCCCCCCCCEEEEECCCCCCCCCCEECCEEEEEEECCEECCCEEEEEEEEHHHHHH
KRYYASSYNELWVAPGAERQVTLAATYTF
HHHHHCCCCEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure 
ALFGAPEPAAADDVPTLALEEAVVRAQAGERLRARRATSATLTDTPLKDVPQSVGVVTR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AALDGFGATRLDTALDWVSGISRQNNLGGIADNFAIRGFAGDLNTGSDYLVNGFSANRAN
HHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCC
SVPVDTINIARIDVLKGPSAALYGRSDPGGIVNIVTRTPQFKPSREITLAAGSHDQYRLA
CCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEE
TELTGPLSGHFAYRLGLAAENNHGFREFSASRRYVIAPSFTWLPTDDTVVTYAFEAAQLR
EECCCCCCCCEEEEEEEEECCCCCHHHHHCCCCEEEECCEEECCCCCCEEEEEEEHHHHC
APFDRGIVAINRQLGALPDSRFLGEPGDGDTTVRTQSHQLSVEHQLGSGWKVDAGLSYRT
CCHHCCEEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEEEECCCCEEEECCCCEEH
SRLFGKSSDASRLLDDGRTLWRQARERDYHANDLAGRVDLQGEVATGPVRHTLVAGADFY
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCEE
NFRYDPVLYRANPSASAPYAIDIFDPVYGQPRPALRPSSSTRESQRGFGAFVQDQVTLTP
CEECCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCEEECC
QWKLLAGVRMDRFLQHADNRLTGARVAQQQTAYSPRLGLVYQPTQTLSLYANTARSFRPN
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHHCCCCC
TGVGAQGNAFAPERGRGYEVGAKLETADGRFGGTLALYSIDKTNVLTGDSRDPVFQRTAG
CCCCCCCCCCCCCCCCCEECCCEEECCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHH
AVRSRGVELDVSGQLTPNLKVLGTYAYTDARVTADTVLPSGAPLSNIPRHSASALGLYEF
HHHHCCEEEEECCCCCCCEEEEEEEEEECCEEEEHHCCCCCCCCCCCCCCCCCEEEEEEC
GAGSLGRAGVGGGVVYVGERAGNSTDNGFKLPAYATVRLNGYVQPTRALRLSLTIDNLFD
CCCCCCCCCCCCCEEEEECCCCCCCCCCEECCEEEEEEECCEECCCEEEEEEEEHHHHHH
KRYYASSYNELWVAPGAERQVTLAATYTF
HHHHHCCCCEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]