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The map label for this gene is hupB2 [H]

Identifier: 17547240

GI number: 17547240

Start: 2728266

End: 2728550

Strand: Direct

Name: hupB2 [H]

Synonym: RSc2521

Alternate gene names: 17547240

Gene position: 2728266-2728550 (Clockwise)

Preceding gene: 17547236

Following gene: 17547242

Centisome position: 73.41

GC content: 61.75

Gene sequence:

>285_bases
ATGACGACCAAATCCGAACTCGTAGCCGCCATTGCCAAAGACGCTGAACTGAGCAACGCCGCCGCCGAGCGCGCGCTGAA
CTCCGCGCTGGAAAACATCAAGAAGACCGTCGCCAAGGGCGGCACCATCACCCTGGTTGGCTTCGGTTCGTTCTCGTCGG
GCAAGCGTGCTGCGCGCACCGGCCGTAACCCGCGCACCGGCGAAGCCATCAAGATCCCGGCGACCAAGACCGTGAAGTTC
ACGGCTGGCAAGGGCTTCAAGGACGCCGTGAACAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
GCAAAGCCTTGCAGTTAGGGGATGTGCAACCTCCCACATCGGTGATATAAAACGGGTCGCAGTACATCGCTGTCCAACAA
ACCTGAAGTGGGGAACTGAC

Downstream 100 bases:

>100_bases
GCGTCTTCTGCCGCGCCCCACGGGGCCGGAAGACCTCGAAGGGACCCAGCCGGGTCCCTTTTCTTTTGGGCGGCGCGCTG
CGCTACGCCACCGGCCAGAG

Product: DNA-binding protein HU-beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MTTKSELVAAIAKDAELSNAAAERALNSALENIKKTVAKGGTITLVGFGSFSSGKRAARTGRNPRTGEAIKIPATKTVKF
TAGKGFKDAVNKKK

Sequences:

>Translated_94_residues
MTTKSELVAAIAKDAELSNAAAERALNSALENIKKTVAKGGTITLVGFGSFSSGKRAARTGRNPRTGEAIKIPATKTVKF
TAGKGFKDAVNKKK
>Mature_93_residues
TTKSELVAAIAKDAELSNAAAERALNSALENIKKTVAKGGTITLVGFGSFSSGKRAARTGRNPRTGEAIKIPATKTVKFT
AGKGFKDAVNKKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=88, Percent_Identity=50, Blast_Score=86, Evalue=4e-19,
Organism=Escherichia coli, GI1790433, Length=87, Percent_Identity=48.2758620689655, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=5e-14,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9765; Mature: 9634

Theoretical pI: Translated: 11.31; Mature: 11.31

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKSELVAAIAKDAELSNAAAERALNSALENIKKTVAKGGTITLVGFGSFSSGKRAART
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHC
GRNPRTGEAIKIPATKTVKFTAGKGFKDAVNKKK
CCCCCCCCEEECCCCCEEEEECCCCCHHHCCCCC
>Mature Secondary Structure 
TTKSELVAAIAKDAELSNAAAERALNSALENIKKTVAKGGTITLVGFGSFSSGKRAART
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHC
GRNPRTGEAIKIPATKTVKFTAGKGFKDAVNKKK
CCCCCCCCEEECCCCCEEEEECCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419967 [H]