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The map label for this gene is nadA [H]

Identifier: 17547168

GI number: 17547168

Start: 2654180

End: 2655328

Strand: Reverse

Name: nadA [H]

Synonym: RSc2449

Alternate gene names: 17547168

Gene position: 2655328-2654180 (Counterclockwise)

Preceding gene: 17547169

Following gene: 17547167

Centisome position: 71.45

GC content: 65.71

Gene sequence:

>1149_bases
ATGGAAACCCACATCAAGACGGTTGAATTCGAGCGCCCGAATATGCTCGCCGAGGCGCAATCCGGGGCCAGTTGCGTCGC
GCACGCCTGGGCCAAGGTGCCGCCGGCTTTGTCACGCGAGGAGCGCGACGCCCTGAAAGCCCGCATCAAGCGTCTGCTCA
AGGAGCGGAATGCAGTGCTGGTCGCGCACTACTACGTCGATGCCGACCTGCAGGACCTGGCCGAGGAGACCGGGGGGTGC
GTGTCGGATTCGCTGGAGATGGCCCGCTTCGGCCGTGACCACTCGGCCAAGACACTGGTGGTGGCAGGCGTGCGCTTCAT
GGGTGAGACCGCCAAGATCCTGAGTCCTGAAAAGACCGTGCTGATGCCGGATCTGGATGCGACCTGCTCGCTGGACCTGG
GTTGTCCGCCGGACACGTTCGCTGCCTTCTGTGACGCGCATCCGGACCGCACTGTCGTCGTCTATGCCAACACCAGCGCC
GCCGTGAAGGCGCGCGCCGACTGGATGGTCACGTCCTCCATCGGCCTGAAGATCGTGCAGCATCTGCACGAGCAGGGACA
GAAGATCCTGTGGGCGCCGGATCGCCACCTGGGTAGCTACATCCAGCAGCAGACCGGCGCCGATATGCTGCTGTGGCAGG
GTTCGTGCCTGGTCCACGACGAGTTCAAGGGCGTGGAGCTGGACCTGCTGCGAGCCGAGCATCCGCACGCCAAGGTGTTG
GTGCATCCGGAGTCGCCGCCATCGGTGGTAGCGCAGGCGGACGTGGTGGGCTCGACCTCGCAGCTGATCGCTGCGGCACA
GTCGCTGCCGGCGGACGCGTTCATCGTCGCGACCGACAACGGCATCCTGCACAAGATGCGCATGGCCGCGCCCGGCAAGC
GTTTCATCGAGGCGCCGACCGCCGGCAACAGCGCCACGTGCAAGAGCTGCGCGCACTGCCCGTGGATGGCGATGAACGCC
TTGACCAACCTGGCCGAGGTGCTCGAGACCGGCCGCAACGAAATCCACGTCGATCCGCAGATCGGCCAGCAGGCGGTGCG
CTGCATTACGCGCATGCTGGACTTCGCCGCGCGCGAGAAAACGACAGTCCGGCCCCAGGGCGATCTGGCGGCCAATACGC
AACTCTTCCAAGGAGTCGGTCCGGCATGA

Upstream 100 bases:

>100_bases
ACAAGGCGCGACCAAGCAGCGCGCTCAGCGTCCTCCACACACACCGTCTGTGATACTGCCGCGCCACTTTTCCCGGCGCC
CACCGGACGGGGAGACCACC

Downstream 100 bases:

>100_bases
CGGCAACCCAGATGACCACCAGCGCAGCGCAGGCGACGTTCGACAGCTTCGGCTCGGCGCTGCGCGAGGCGTTGGCCGCC
AACGTGGCGGCCGCCATCCG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVLVAHYYVDADLQDLAEETGGC
VSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSA
AVKARADWMVTSSIGLKIVQHLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVL
VHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPTAGNSATCKSCAHCPWMAMNA
LTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREKTTVRPQGDLAANTQLFQGVGPA

Sequences:

>Translated_382_residues
METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVLVAHYYVDADLQDLAEETGGC
VSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSA
AVKARADWMVTSSIGLKIVQHLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVL
VHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPTAGNSATCKSCAHCPWMAMNA
LTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREKTTVRPQGDLAANTQLFQGVGPA
>Mature_382_residues
METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVLVAHYYVDADLQDLAEETGGC
VSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTVLMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSA
AVKARADWMVTSSIGLKIVQHLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVL
VHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPTAGNSATCKSCAHCPWMAMNA
LTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREKTTVRPQGDLAANTQLFQGVGPA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=326, Percent_Identity=66.5644171779141, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEE
VAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTV
EEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEE
LMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKIVQ
EECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHH
HLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVL
HHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEE
VHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPT
ECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCEEECCC
AGNSATCKSCAHCPWMAMNALTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREK
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
TTVRPQGDLAANTQLFQGVGPA
CCCCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
METHIKTVEFERPNMLAEAQSGASCVAHAWAKVPPALSREERDALKARIKRLLKERNAVL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEE
VAHYYVDADLQDLAEETGGCVSDSLEMARFGRDHSAKTLVVAGVRFMGETAKILSPEKTV
EEEEEECCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEE
LMPDLDATCSLDLGCPPDTFAAFCDAHPDRTVVVYANTSAAVKARADWMVTSSIGLKIVQ
EECCCCCCEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHH
HLHEQGQKILWAPDRHLGSYIQQQTGADMLLWQGSCLVHDEFKGVELDLLRAEHPHAKVL
HHHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEECCCCCCEEE
VHPESPPSVVAQADVVGSTSQLIAAAQSLPADAFIVATDNGILHKMRMAAPGKRFIEAPT
ECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCEEECCC
AGNSATCKSCAHCPWMAMNALTNLAEVLETGRNEIHVDPQIGQQAVRCITRMLDFAAREK
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
TTVRPQGDLAANTQLFQGVGPA
CCCCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA