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The map label for this gene is yhcK [H]

Identifier: 17547151

GI number: 17547151

Start: 2637302

End: 2638957

Strand: Reverse

Name: yhcK [H]

Synonym: RSc2432

Alternate gene names: 17547151

Gene position: 2638957-2637302 (Counterclockwise)

Preceding gene: 17547152

Following gene: 17547145

Centisome position: 71.01

GC content: 69.93

Gene sequence:

>1656_bases
GTGGCCAAGCCCGCCCGCCCGCCTCAAGTCCGCGTCCGGCACATCGTGCGGGTGGGGCTGGCGTTGTCGATGCTGCTGGC
GGGCGCCGCCCTGTGCTGGTTCGCCGCAGGCATGGTGGCGGATGCGATGGGTGCGCGCGAGCTGCGGCAGACGTTCGATG
CGCGCCGCCAGCTGGCCGAGCAAGTGGCCGACGGGATGGCCAGCCAGATCACCGCCGACGTGGCGCTGCTGCGCGCCGTG
CCGCTGACGCTGGCGGAGATCGAGTCGATTCCTGCCGGCGTGGCGCGCGTCGATACGCGCCGCTGGAACCTGATGGATGA
AGGCTTGCGCCTCAAGGAGGCGACGGCCCATCCCGAGGTGCGGGCCGCGAGCACGTTCCTGAGCGTCGCCAACGGCAATC
TCGGGCTGGACTACACCTGGGTGGTCGACACGCGCGGCTACGTGGTGCTGGCCAGCAACGCGGGGCGGCCCGGTTCGTTC
ATCGGCATGCAGTTGGCGCTCCAGCCGTACATGAAGGCGGCCATGCTGGGCGGCCTCGGCGAGCAGTTCACTGTCGGCCC
GATTACGGGCGTGCCGGGGCTGTTCTTCGCCGCGCCGATCTACGATGCCCAGGGCCGCCTGGTGGCGGCGATCGGCACTA
AGCTCAACCTGTCGCGCCTGCAGCACTGGGTGTCGCACCCGACCTCGCTGGTGGCGGACGCGAACGGGCTGATCATCCTG
TCGACCGACGCCTCGCTGGTGGGCAAGGCGCTACCCGATTCGCGCGTGCAGCGGATGACGCCGTCCGAGCGCTTCACCGA
GTACCAGCGGGTGGATTTCGAGCCGTGGTCTTACCAGGCGGCCGCATCGGCGCAGCGGGCGGTGCCGTCGTGGGTTCCCG
CCGATGTGCGCGATGCCATGGTGTGGCGCGCGGGCAGTGAGATCCCCTCGCTGACAGTCTCGCGCACTGCCAGCGCAGAC
CTGACCGTGATGGTGGCGGAGCCGTTGGGGTCGTGGTCGTATCAGTTGGCCACCCACGAGCGCAATCGCTCGCTGGGTTT
CGTGCTGTTCCTCAGCGGGCTGCTGGTCTTCGTGCTGGTGGTGTGGTCCCTGCTGCGGGAGCGCCAGCACCATCGCGTGA
CCCGCCACCTCAATCAGAGCCTGCAGCGCACCAACAGCGCGCTCGCCAACGAAGCCCATTTCGACCACCTGACCGGTGTG
CTGACGCGGCGGCGCTTTCTCGCCCTGTTCGAAACCGTGCTGACACGCACCCATGTGCGCGGCGAGCAACTGGTGCTGGT
CCTGGCGGACCTGGACCACTTCAAGCGCATCAACGACACCTGGGGCCATGCGGTGGGGGATCTCGCCCTGCAGCGCTTCG
CCTCGCTCGCCACCAGCGTGATGCGCAGCAGCGACCTGATCGGCCGGCTGGGCGGCGAGGAGTTCGCCGTGGTCATGGGC
CGCACCACCCTCGAAGAGGCGGCCGGCGTGGTCGAGCGCCTGCGCGCGGCCGTGGCCGAAGCGGACGCATCCCTGCCCAG
CGGACTGGCCATGACGGTGAGCCTCGGCATGACGGCCTGCCACACCGGCGACACCGCTTCGGAGATGCTCAGGCGCGCCG
ACCTGGCGCTCTACCGCGCCAAGGAAAGCGGGCGGAACCGGCACGCGGCGGGTTAG

Upstream 100 bases:

>100_bases
AGCGAATCGCGCCGTCTGCGCAGCGTGCGCCTCGCGCGCGAACTGCGGCTGGCGCTGCGGTATCCGACCGTCGCCGACTT
CCTGGCGGGCGGGGGCTGAC

Downstream 100 bases:

>100_bases
GAGCGCGGCGCCGATGCCTTTACGCGCAAGCCGGCCGCTCAGTTCGGCGTACGGCGTGCGCGCCTGCGCCGCAGTTCGAG
CTGCACGCGGGCGCCTGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MAKPARPPQVRVRHIVRVGLALSMLLAGAALCWFAAGMVADAMGARELRQTFDARRQLAEQVADGMASQITADVALLRAV
PLTLAEIESIPAGVARVDTRRWNLMDEGLRLKEATAHPEVRAASTFLSVANGNLGLDYTWVVDTRGYVVLASNAGRPGSF
IGMQLALQPYMKAAMLGGLGEQFTVGPITGVPGLFFAAPIYDAQGRLVAAIGTKLNLSRLQHWVSHPTSLVADANGLIIL
STDASLVGKALPDSRVQRMTPSERFTEYQRVDFEPWSYQAAASAQRAVPSWVPADVRDAMVWRAGSEIPSLTVSRTASAD
LTVMVAEPLGSWSYQLATHERNRSLGFVLFLSGLLVFVLVVWSLLRERQHHRVTRHLNQSLQRTNSALANEAHFDHLTGV
LTRRRFLALFETVLTRTHVRGEQLVLVLADLDHFKRINDTWGHAVGDLALQRFASLATSVMRSSDLIGRLGGEEFAVVMG
RTTLEEAAGVVERLRAAVAEADASLPSGLAMTVSLGMTACHTGDTASEMLRRADLALYRAKESGRNRHAAG

Sequences:

>Translated_551_residues
MAKPARPPQVRVRHIVRVGLALSMLLAGAALCWFAAGMVADAMGARELRQTFDARRQLAEQVADGMASQITADVALLRAV
PLTLAEIESIPAGVARVDTRRWNLMDEGLRLKEATAHPEVRAASTFLSVANGNLGLDYTWVVDTRGYVVLASNAGRPGSF
IGMQLALQPYMKAAMLGGLGEQFTVGPITGVPGLFFAAPIYDAQGRLVAAIGTKLNLSRLQHWVSHPTSLVADANGLIIL
STDASLVGKALPDSRVQRMTPSERFTEYQRVDFEPWSYQAAASAQRAVPSWVPADVRDAMVWRAGSEIPSLTVSRTASAD
LTVMVAEPLGSWSYQLATHERNRSLGFVLFLSGLLVFVLVVWSLLRERQHHRVTRHLNQSLQRTNSALANEAHFDHLTGV
LTRRRFLALFETVLTRTHVRGEQLVLVLADLDHFKRINDTWGHAVGDLALQRFASLATSVMRSSDLIGRLGGEEFAVVMG
RTTLEEAAGVVERLRAAVAEADASLPSGLAMTVSLGMTACHTGDTASEMLRRADLALYRAKESGRNRHAAG
>Mature_550_residues
AKPARPPQVRVRHIVRVGLALSMLLAGAALCWFAAGMVADAMGARELRQTFDARRQLAEQVADGMASQITADVALLRAVP
LTLAEIESIPAGVARVDTRRWNLMDEGLRLKEATAHPEVRAASTFLSVANGNLGLDYTWVVDTRGYVVLASNAGRPGSFI
GMQLALQPYMKAAMLGGLGEQFTVGPITGVPGLFFAAPIYDAQGRLVAAIGTKLNLSRLQHWVSHPTSLVADANGLIILS
TDASLVGKALPDSRVQRMTPSERFTEYQRVDFEPWSYQAAASAQRAVPSWVPADVRDAMVWRAGSEIPSLTVSRTASADL
TVMVAEPLGSWSYQLATHERNRSLGFVLFLSGLLVFVLVVWSLLRERQHHRVTRHLNQSLQRTNSALANEAHFDHLTGVL
TRRRFLALFETVLTRTHVRGEQLVLVLADLDHFKRINDTWGHAVGDLALQRFASLATSVMRSSDLIGRLGGEEFAVVMGR
TTLEEAAGVVERLRAAVAEADASLPSGLAMTVSLGMTACHTGDTASEMLRRADLALYRAKESGRNRHAAG

Specific function: Unknown

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=167, Percent_Identity=38.9221556886228, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787262, Length=218, Percent_Identity=31.1926605504587, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786584, Length=154, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082007, Length=184, Percent_Identity=38.5869565217391, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI145693134, Length=208, Percent_Identity=33.1730769230769, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=32.5301204819277, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788381, Length=163, Percent_Identity=34.9693251533742, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=34.3558282208589, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=32.484076433121, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=29.4797687861272, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787541, Length=162, Percent_Identity=30.2469135802469, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=29.1925465838509, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=32.7380952380952, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 59852; Mature: 59720

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPARPPQVRVRHIVRVGLALSMLLAGAALCWFAAGMVADAMGARELRQTFDARRQLAE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADGMASQITADVALLRAVPLTLAEIESIPAGVARVDTRRWNLMDEGLRLKEATAHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCHHHCCCCHHHHCCCCCH
RAASTFLSVANGNLGLDYTWVVDTRGYVVLASNAGRPGSFIGMQLALQPYMKAAMLGGLG
HHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
EQFTVGPITGVPGLFFAAPIYDAQGRLVAAIGTKLNLSRLQHWVSHPTSLVADANGLIIL
CCCEECCCCCCCHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHEECCCCEEEE
STDASLVGKALPDSRVQRMTPSERFTEYQRVDFEPWSYQAAASAQRAVPSWVPADVRDAM
ECCHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
VWRAGSEIPSLTVSRTASADLTVMVAEPLGSWSYQLATHERNRSLGFVLFLSGLLVFVLV
HHHCCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
VWSLLRERQHHRVTRHLNQSLQRTNSALANEAHFDHLTGVLTRRRFLALFETVLTRTHVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEQLVLVLADLDHFKRINDTWGHAVGDLALQRFASLATSVMRSSDLIGRLGGEEFAVVMG
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
RTTLEEAAGVVERLRAAVAEADASLPSGLAMTVSLGMTACHTGDTASEMLRRADLALYRA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHH
KESGRNRHAAG
HHCCCCCCCCC
>Mature Secondary Structure 
AKPARPPQVRVRHIVRVGLALSMLLAGAALCWFAAGMVADAMGARELRQTFDARRQLAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADGMASQITADVALLRAVPLTLAEIESIPAGVARVDTRRWNLMDEGLRLKEATAHPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCHHHCCCCHHHHCCCCCH
RAASTFLSVANGNLGLDYTWVVDTRGYVVLASNAGRPGSFIGMQLALQPYMKAAMLGGLG
HHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
EQFTVGPITGVPGLFFAAPIYDAQGRLVAAIGTKLNLSRLQHWVSHPTSLVADANGLIIL
CCCEECCCCCCCHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHEECCCCEEEE
STDASLVGKALPDSRVQRMTPSERFTEYQRVDFEPWSYQAAASAQRAVPSWVPADVRDAM
ECCHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
VWRAGSEIPSLTVSRTASADLTVMVAEPLGSWSYQLATHERNRSLGFVLFLSGLLVFVLV
HHHCCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
VWSLLRERQHHRVTRHLNQSLQRTNSALANEAHFDHLTGVLTRRRFLALFETVLTRTHVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEQLVLVLADLDHFKRINDTWGHAVGDLALQRFASLATSVMRSSDLIGRLGGEEFAVVMG
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
RTTLEEAAGVVERLRAAVAEADASLPSGLAMTVSLGMTACHTGDTASEMLRRADLALYRA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHH
KESGRNRHAAG
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]