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The map label for this gene is cysI1 [H]

Identifier: 17547144

GI number: 17547144

Start: 2628961

End: 2630622

Strand: Reverse

Name: cysI1 [H]

Synonym: RSc2425

Alternate gene names: 17547144

Gene position: 2630622-2628961 (Counterclockwise)

Preceding gene: 17547145

Following gene: 17547143

Centisome position: 70.78

GC content: 64.74

Gene sequence:

>1662_bases
ATGTACCAATACGACGCCTACGATCATCGCCTCGTCGCCGACCGCGTCGCGCAGTTCCGCGACCAGGTGCGCCGCCGCAT
CTCGGGCGAGCTGACGGAAGAGGAATTCCTGCCGCTGCGCCTGCAGAACGGCCTGTACATGCAGCGCCACGCTTACATGC
TGCGCGTGGCCATTCCATATGGCCACCTGCGTGCCAAGCAACTGCGCATGCTCAGCCACATCGCCGCCGAACACGATCGC
GGCTATGGCCACTTCAGCACGCGCCAGAACATTCAGTACAACTGGATCAAGCTCGAAGACGTGCCGGACATCCTGGGCAA
GCTGGCTTCGGTGGAAATGCACGCCATCCAGACCTCGGGCAACTGCATCCGCAACATCACGACCGACCAGTTTGCCGGCG
TGGCGCCGGATGAGTTCGTCGACCCGCGTCCGCTGGCCGAGATCCTGCGCCAGTGGTCGACCTTCATTCCCGAGTTCGCC
TTCCTGCCGCGCAAGTTCAAGATCGCCGTCTCGGCCACGCGCGAAGACCGCGCGGTGACGCAACTGCACGACATCGGCGT
GTACGCCTATGAAAAGGACGGCCGGACGCTGCTGCGTGTCCTGGCCGGCGGCGGCATGGGCCGTACCCCGATCCTGGGCG
CGATCATCAAGGAAGATCTGCCGTGGCAGCACATGCTGTCGTACATCGAAGCGGCCATCCGCGTGTACAACCGCTATGGC
CGCCGCGACAACAAGTACAAGGCGCGCATCAAGATCCTGGTGAAGGCCATCGGTGCGGAAGAATTCGCCCGCCAGGTGGA
AGAGGAATGGCAGCACATCAAGGACGGCCCGTCGACCATCCCGCAGGCCGAGTTCGACCGCGTGGCGAAGGACTTCGCAC
CGCCCGCGTATGAAAAGCTGGCCGACACCGACGCCGCCTACGAGAAGGCGCTGCTCGAGAACAAGGCGTTCGCGCGCTGG
GTCAGCCGCAATGTGCATCCGCACCGCGTGCCGGGCTATGCGGCGGTGACGCTGTCGCTCAAGCCGGGCGTGGCCCTGCC
TCCGGGGGACGCCACCGCCGAGCAGATGGCGCTGGTGGCCGACTGGTCCGAGCGCTTCGGCTTCGGCGAGCTGCGCGTGG
CGCACGAGCAGAACCTGATCCTGCCGGACGTGAAGAAGCACGACCTGTTCGCGCTGTGGCAGCTGGCCAAGGAACACGGC
ATGGCCACCGCCAACATCGGCCTGCTGACCGACATCATCGCCTGCCCGGGCGGCGACTTCTGCTCGCTGGCGAACGCCAA
GTCGATTCCCATCGCGCAGGCCATCCAGGCGCGTTTCGACAATCTGGACTACGTGCACGACCTGGGCGAGATCTCGCTCA
ACATCTCGGGCTGCATCAATTCGTGCGGCCACCACCACGTCGGCAACATCGGCATCCTGGGTGTCGACAAGGCCGACGAG
GAGTGGTACCAGGTGTCGCTGGGCGGCGCGCAGGGCAACGATTCGGCGCTCGGCAAGGTGATCGGCCCGTCGTTCAAGGC
CGAGGAGATGCCCGACGTGATCGAGCGCATCATCGACACCTTCGTCGCCAACCGGATCGAAGACGAGCGCTTCATCGAAA
CCTACAACCGCATCGGCATGACCCCGTTCAAGGAACGCGTCTATGCCCGTGAAGCTGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTGCTGTGGCGGCTGAGCCGGCACCAGCAGCAAGGCAACGAACCTTTCCCCCATTTGAATCGCATGCCGGCGCAAG
CCGGATCGGACTGACCAGTC

Downstream 100 bases:

>100_bases
GCCCGAGGGAACGAACATGAGCAAGATCATCAAGCTGCAAGACGGCACCCCGCAGATCGTTGCCGACGAGTGGACCGTGC
TGCGCGCCCCCGAGGGCGGC

Product: sulfite reductase oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYMQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIKLEDVPDILGKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEFVDPRPLAEILRQWSTFIPEFA
FLPRKFKIAVSATREDRAVTQLHDIGVYAYEKDGRTLLRVLAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAIRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTIPQAEFDRVAKDFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGVALPPGDATAEQMALVADWSERFGFGELRVAHEQNLILPDVKKHDLFALWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDNLDYVHDLGEISLNISGCINSCGHHHVGNIGILGVDKADE
EWYQVSLGGAQGNDSALGKVIGPSFKAEEMPDVIERIIDTFVANRIEDERFIETYNRIGMTPFKERVYAREAA

Sequences:

>Translated_553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYMQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIKLEDVPDILGKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEFVDPRPLAEILRQWSTFIPEFA
FLPRKFKIAVSATREDRAVTQLHDIGVYAYEKDGRTLLRVLAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAIRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTIPQAEFDRVAKDFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGVALPPGDATAEQMALVADWSERFGFGELRVAHEQNLILPDVKKHDLFALWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDNLDYVHDLGEISLNISGCINSCGHHHVGNIGILGVDKADE
EWYQVSLGGAQGNDSALGKVIGPSFKAEEMPDVIERIIDTFVANRIEDERFIETYNRIGMTPFKERVYAREAA
>Mature_553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYMQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIKLEDVPDILGKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEFVDPRPLAEILRQWSTFIPEFA
FLPRKFKIAVSATREDRAVTQLHDIGVYAYEKDGRTLLRVLAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAIRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTIPQAEFDRVAKDFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGVALPPGDATAEQMALVADWSERFGFGELRVAHEQNLILPDVKKHDLFALWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDNLDYVHDLGEISLNISGCINSCGHHHVGNIGILGVDKADE
EWYQVSLGGAQGNDSALGKVIGPSFKAEEMPDVIERIIDTFVANRIEDERFIETYNRIGMTPFKERVYAREAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 62377; Mature: 62377

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYMQRHAYMLRVAIPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCEEEECCEEEEEEECCC
GHLRAKQLRMLSHIAAEHDRGYGHFSTRQNIQYNWIKLEDVPDILGKLASVEMHAIQTSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHEEEECCC
NCIRNITTDQFAGVAPDEFVDPRPLAEILRQWSTFIPEFAFLPRKFKIAVSATREDRAVT
CHHHCCCHHHHCCCCCHHCCCCCHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCHHHHH
QLHDIGVYAYEKDGRTLLRVLAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAIRVYNRYG
HHHHCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTIPQAEFDRVAKDFAPPAYEKL
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHH
ADTDAAYEKALLENKAFARWVSRNVHPHRVPGYAAVTLSLKPGVALPPGDATAEQMALVA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
DWSERFGFGELRVAHEQNLILPDVKKHDLFALWQLAKEHGMATANIGLLTDIIACPGGDF
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCC
CSLANAKSIPIAQAIQARFDNLDYVHDLGEISLNISGCINSCGHHHVGNIGILGVDKADE
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHCCCCCCCCCEEEEECCCCCC
EWYQVSLGGAQGNDSALGKVIGPSFKAEEMPDVIERIIDTFVANRIEDERFIETYNRIGM
CEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
TPFKERVYAREAA
CHHHHHHHHHCCC
>Mature Secondary Structure
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYMQRHAYMLRVAIPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCEEEECCEEEEEEECCC
GHLRAKQLRMLSHIAAEHDRGYGHFSTRQNIQYNWIKLEDVPDILGKLASVEMHAIQTSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHEEEECCC
NCIRNITTDQFAGVAPDEFVDPRPLAEILRQWSTFIPEFAFLPRKFKIAVSATREDRAVT
CHHHCCCHHHHCCCCCHHCCCCCHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCHHHHH
QLHDIGVYAYEKDGRTLLRVLAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAIRVYNRYG
HHHHCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTIPQAEFDRVAKDFAPPAYEKL
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHH
ADTDAAYEKALLENKAFARWVSRNVHPHRVPGYAAVTLSLKPGVALPPGDATAEQMALVA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
DWSERFGFGELRVAHEQNLILPDVKKHDLFALWQLAKEHGMATANIGLLTDIIACPGGDF
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCC
CSLANAKSIPIAQAIQARFDNLDYVHDLGEISLNISGCINSCGHHHVGNIGILGVDKADE
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHCCCCCCCCCEEEEECCCCCC
EWYQVSLGGAQGNDSALGKVIGPSFKAEEMPDVIERIIDTFVANRIEDERFIETYNRIGM
CEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
TPFKERVYAREAA
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA