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The map label for this gene is hpaF [H]

Identifier: 17547138

GI number: 17547138

Start: 2623746

End: 2624150

Strand: Reverse

Name: hpaF [H]

Synonym: RSc2419

Alternate gene names: 17547138

Gene position: 2624150-2623746 (Counterclockwise)

Preceding gene: 17547139

Following gene: 17547134

Centisome position: 70.61

GC content: 65.19

Gene sequence:

>405_bases
ATGCCGCATCTCATCATCGAATACACCGCCAATGTCGAGGCCGACGCTCGCATTCCCGAGTTGATGCGGGTGCTCAACGA
CGTGGTGATTGCCCATGCCGACGTCTTCCCGATCGGCGGCATCCGCACGCGCGCGCTGCGCCTGGATCAATACCGCATGG
CCGACGGCGCCGAAAACGATGCTTTCATCCACGTCACGTTTCGCATCAAGGCCGGCCGGCCCAGGGCGCAGACGCAGCGG
GTCTGCGCCGATCTGTTCGCGGCGCTGCGGGGGCATCTGGCTGAAGTCTTCGCCCGCCGGTATCTGGGCCTGACCCTCGA
ACTGGATGAGTTCGACACGCACGGCTTCCACGTCGAGAACAACGTGCATGCCCGCTTCGTGCCGGCGGTCGAAGCGCGGC
GGTAG

Upstream 100 bases:

>100_bases
CTGTTGCATGTGATCTGGGGGTCTCTTGAACCTCCCCGCTTTGTTGGTACGCTGTTCACAAAATACGCTGTTCAGTCTTT
ATTCCCGGGGGGGAATCCTG

Downstream 100 bases:

>100_bases
GCGTCAGCCGAGCTGGCGGGTGCAGTAGGCGGCGATGGCGTCGAGCACAGCGTCGTCTTCGCCGACAGCCTCGGCGCAGC
GGATCGGCAGGGCGGGGTGC

Product: 5-carboxymethyl-2-hydroxymuconate DELTA-isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MPHLIIEYTANVEADARIPELMRVLNDVVIAHADVFPIGGIRTRALRLDQYRMADGAENDAFIHVTFRIKAGRPRAQTQR
VCADLFAALRGHLAEVFARRYLGLTLELDEFDTHGFHVENNVHARFVPAVEARR

Sequences:

>Translated_134_residues
MPHLIIEYTANVEADARIPELMRVLNDVVIAHADVFPIGGIRTRALRLDQYRMADGAENDAFIHVTFRIKAGRPRAQTQR
VCADLFAALRGHLAEVFARRYLGLTLELDEFDTHGFHVENNVHARFVPAVEARR
>Mature_133_residues
PHLIIEYTANVEADARIPELMRVLNDVVIAHADVFPIGGIRTRALRLDQYRMADGAENDAFIHVTFRIKAGRPRAQTQRV
CADLFAALRGHLAEVFARRYLGLTLELDEFDTHGFHVENNVHARFVPAVEARR

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 15217; Mature: 15085

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLIIEYTANVEADARIPELMRVLNDVVIAHADVFPIGGIRTRALRLDQYRMADGAEND
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCCCCCCCC
AFIHVTFRIKAGRPRAQTQRVCADLFAALRGHLAEVFARRYLGLTLELDEFDTHGFHVEN
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECC
NVHARFVPAVEARR
CCCEEEECCCCCCC
>Mature Secondary Structure 
PHLIIEYTANVEADARIPELMRVLNDVVIAHADVFPIGGIRTRALRLDQYRMADGAEND
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCCCCCCCC
AFIHVTFRIKAGRPRAQTQRVCADLFAALRGHLAEVFARRYLGLTLELDEFDTHGFHVEN
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECC
NVHARFVPAVEARR
CCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]