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The map label for this gene is btuC [C]

Identifier: 17547118

GI number: 17547118

Start: 2605989

End: 2606996

Strand: Reverse

Name: btuC [C]

Synonym: RSc2399

Alternate gene names: 17547118

Gene position: 2606996-2605989 (Counterclockwise)

Preceding gene: 17547119

Following gene: 17547117

Centisome position: 70.15

GC content: 73.31

Gene sequence:

>1008_bases
ATGACACCCGCATTGCCCGCGCGCGGTTTTGCCTGGCGACTGTGGTCGCTGCTGGCGCTCGCGTGCGTGGCGGTGCTGGT
GGCCTCGCTGATGCTGGGCAGCGTGCGGCTGTCGCCCGCGCAGGTGTGGCAGGCGCTGACCGGCAGCGGCGATGGCCTGG
CCACCGGCATCGTCACCGGGCTGCGCCTGCCGAGGGCCGGGGCGGCTTTTGCCTGCGGCGCGCTGCTGGCGCTGGCCGGC
GCGCTGATGCAGATGCTGCTGCGCAATCCGCTGGCCGATCCGTATGTGCTGGGTGTGTCGGGCGGCGGCGCGGTGGCGGC
GTTGACGGCCATGCTGCTGTCGTTGCCGTGGTGGGCCGTGCAGGCCGGCGCGGGGGCGGGCGCGCTGGCATCGATGGCGC
TGGTGGCCGCTCTGGCGCGGCAGCACCTGTGGCGCGGCGAACCGGGTGAGGCCAACGCGCGCCTGCTGCTGGCCGGCGTG
GTGCTGGCCTCGGGCTGGGTCGGCCTGATCACGCTGATCCTGACCGTGGCGCCCGAGGCCAAGCTGCGCGGCATGATCTT
CTGGATGGTCGGCGACCTGGGCGGTGCCGACCGCTATCTCGGGGCGCTGATGGCGCTGGTGGCCGCGCTGGCCCTGGTGC
TGCCGCATGCGCGCGACCTCAATGTGCTGCTGACCGGCGAGATGCGCGCGCGTGCGCTGGGCGTGCCGGTGGCGCGGGTG
CGGGCGCTGATCTACGTGGTGGCCTCGCTGTGCACCGCGGTGGCGGTGACGATTGCGGGGTCGGTCGCCTTTGTCGGCCT
GCTGGTGCCGCACATGGTGCGGCTGGCGTGGACGCACGATGTGCGCATCCACCTGCCAGCCACCGCGATGGCCGGCGGCG
GCCTGCTGATGCTGGCCGACCTGATCGCCCGCACGCTGATCGCGCCGGCGCAGTTGCCGGTGGGGGTGATCACCACGCTG
CTGGGCGTGCCGACCTTTCTCTACCTGCTGATGCGGAGCGCGCGATGA

Upstream 100 bases:

>100_bases
AGAACCTGCTCAACAAGAACTACCAGCTGATCGCCCCATACAACACGGCATCGCGCGGGGTGTTCTTCACGCTGTCGTGG
CAACAGCACGCACCGCAACG

Downstream 100 bases:

>100_bases
GCTGGCTGCGCCGCGCCGCCGTCACCGATGCGTTCGCGCAGGCCGCCGACGCGCCCGCGCTGGCGCTGCGCGAGCTGCGC
GTGACGATGGGCGGGCGGGT

Product: transmembrane ABC transporter protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTPALPARGFAWRLWSLLALACVAVLVASLMLGSVRLSPAQVWQALTGSGDGLATGIVTGLRLPRAGAAFACGALLALAG
ALMQMLLRNPLADPYVLGVSGGGAVAALTAMLLSLPWWAVQAGAGAGALASMALVAALARQHLWRGEPGEANARLLLAGV
VLASGWVGLITLILTVAPEAKLRGMIFWMVGDLGGADRYLGALMALVAALALVLPHARDLNVLLTGEMRARALGVPVARV
RALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTHDVRIHLPATAMAGGGLLMLADLIARTLIAPAQLPVGVITTL
LGVPTFLYLLMRSAR

Sequences:

>Translated_335_residues
MTPALPARGFAWRLWSLLALACVAVLVASLMLGSVRLSPAQVWQALTGSGDGLATGIVTGLRLPRAGAAFACGALLALAG
ALMQMLLRNPLADPYVLGVSGGGAVAALTAMLLSLPWWAVQAGAGAGALASMALVAALARQHLWRGEPGEANARLLLAGV
VLASGWVGLITLILTVAPEAKLRGMIFWMVGDLGGADRYLGALMALVAALALVLPHARDLNVLLTGEMRARALGVPVARV
RALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTHDVRIHLPATAMAGGGLLMLADLIARTLIAPAQLPVGVITTL
LGVPTFLYLLMRSAR
>Mature_334_residues
TPALPARGFAWRLWSLLALACVAVLVASLMLGSVRLSPAQVWQALTGSGDGLATGIVTGLRLPRAGAAFACGALLALAGA
LMQMLLRNPLADPYVLGVSGGGAVAALTAMLLSLPWWAVQAGAGAGALASMALVAALARQHLWRGEPGEANARLLLAGVV
LASGWVGLITLILTVAPEAKLRGMIFWMVGDLGGADRYLGALMALVAALALVLPHARDLNVLLTGEMRARALGVPVARVR
ALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTHDVRIHLPATAMAGGGLLMLADLIARTLIAPAQLPVGVITTLL
GVPTFLYLLMRSAR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=283, Percent_Identity=39.9293286219081, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1790740, Length=275, Percent_Identity=37.8181818181818, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1790741, Length=328, Percent_Identity=35.0609756097561, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=37.3801916932907, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=32.0284697508897, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786804, Length=327, Percent_Identity=36.3914373088685, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34433; Mature: 34302

Theoretical pI: Translated: 11.58; Mature: 11.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPALPARGFAWRLWSLLALACVAVLVASLMLGSVRLSPAQVWQALTGSGDGLATGIVTG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHH
LRLPRAGAAFACGALLALAGALMQMLLRNPLADPYVLGVSGGGAVAALTAMLLSLPWWAV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
QAGAGAGALASMALVAALARQHLWRGEPGEANARLLLAGVVLASGWVGLITLILTVAPEA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCH
KLRGMIFWMVGDLGGADRYLGALMALVAALALVLPHARDLNVLLTGEMRARALGVPVARV
HHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCHHHH
RALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTHDVRIHLPATAMAGGGLLMLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCHHHHHHH
LIARTLIAPAQLPVGVITTLLGVPTFLYLLMRSAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPALPARGFAWRLWSLLALACVAVLVASLMLGSVRLSPAQVWQALTGSGDGLATGIVTG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHH
LRLPRAGAAFACGALLALAGALMQMLLRNPLADPYVLGVSGGGAVAALTAMLLSLPWWAV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
QAGAGAGALASMALVAALARQHLWRGEPGEANARLLLAGVVLASGWVGLITLILTVAPEA
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCH
KLRGMIFWMVGDLGGADRYLGALMALVAALALVLPHARDLNVLLTGEMRARALGVPVARV
HHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCCHHHH
RALIYVVASLCTAVAVTIAGSVAFVGLLVPHMVRLAWTHDVRIHLPATAMAGGGLLMLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHCCCHHHHHHH
LIARTLIAPAQLPVGVITTLLGVPTFLYLLMRSAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]