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The map label for this gene is adi [H]

Identifier: 17547084

GI number: 17547084

Start: 2568237

End: 2570516

Strand: Reverse

Name: adi [H]

Synonym: RSc2365

Alternate gene names: 17547084

Gene position: 2570516-2568237 (Counterclockwise)

Preceding gene: 17547085

Following gene: 17547083

Centisome position: 69.17

GC content: 65.04

Gene sequence:

>2280_bases
ATGAAATTCCGTTTTCCCGTCATCATCATCGACGAGGACTTCCGCTCCGAGAACATCTCCGGGTCGGGCATTCGCGCGCT
GGCGCAGGCCATCGAAGAAGAGGGCATGGAGGTCACGGGCCTGACCAGCTATGGCGACCTGACCTCGTTCGCGCAGCAGT
CGAGCCGGGCGTCCACCTTCATCGTCTCGATCGACGACGATGAGTTCATCAACCCGGACAACGACAAGCCGGAACCGGAA
GCGGTGGAAAACCTGCGCAGCTTCGTGGCCGAAGTGCGCCGCCGCAACGCCAACATCCCCATCTTCCTGTACGGCGAGAC
GCGCACCTCGCGCCACCTGCCCAACGACATCCTGCGCGAGCTGCACGGCTTCATCCACATGTTCGAGGACACGCCGGAGT
TCGTGGCGCGCCACATCATCCGCGAAGCCCGCAACTACCTGGATTCGCTGCCGCCGCCGTTCTTCAAGGCGCTGATCGAC
TACGCGCAGGACAGCTCCTACTCGTGGCACTGCCCGGGGCACTCGGGCGGCGTGGCGTTCCTCAAGAGCCCGGTGGGCCA
GGTGTTCCACCAGTTCTTCGGCGAGAACATGCTGCGCGCCGACGTCTGCAACGCGGTGGACGAGCTCGGCCAGCTGCTCG
ACCACACCGGCCCGGTGGCGGCCTCCGAGCGCAATGCCGCGCGCATCTTCGGCTCGGACCACATGTTCTTCGTCACCAAC
GGCACGTCCACCTCGAACAAGATGGTGTGGCACGCCAACGTGGCGCCCGGCGACATCGTGGTGGTGGACCGCAACTGCCA
CAAGTCGATCCTGCACGCGATCATGATGACGGGCGCGATCCCCGTGTTCCTGATGCCGACGCGCAACCACTACGGCATCA
TCGGCCCGATTCCGCAGAGCGAGTTCGAGCCCGAGACCATCGCCCGCAAGATCGCCGAGCATCCGTTCGCCAGCCAGGCC
GCGAACAAGAAGCCGCGCATCCTGACCCTCACGCAGGGCACGTACGACGGCGTGCTGTACAACGCCGAGCGCATCAAGCA
CATGCTGTCGACCGAGATCGACACGCTGCACTTCGACGAGGCCTGGCTGCCGCACGCCTCGTTCCACCCGTTCTACCGCG
ACATGCACGCCATCGGCCAGGGCCGCGCGCGCAGCAAGGACGCGCTGGTGTTCGCCACGCAGAGCACGCACAAGCTGCTG
GCCGGCCTGTCTCAGGCTTCGCAGATCCTCGTGCAGGATTCCGAGACGCGCAAGCTCGACACGTACCGCTTCAACGAGGC
GTACCTGATGCACACCTCGACCAGCCCGCAGTACTCGATCATCGCCTCGTGCGACGTGGCCGCGGCGATGATGGAAGCGC
CGGGCGGCACCGCGCTGGTGGAAGAGAGCATCGCCGAGGCCCTGGACTTCCGCCGCGCCATGCGCAAGGTGGAGCAGGAG
TACGTCGGCACGAATGGTGGCAACGGCCGCGGCGACGACTGGTGGTTCAAGGTCTGGGGCCCGAACGACCTGTCCGATGA
AGGCATCGAGGAGCGCGAGGCCTGGATGCTCAAGGCCAACGAGCGCTGGCACGGCTTCGGCGACCTGGCCGAGGACTTCA
ACCTGCTCGACCCGATCAAGGCCACCATCATCACCCCGGGCCTGGACGTGGACGGCAAGTTCAGCGAGTCGGGCATCCCG
GCGGCCATCGTCACGAAGTACCTCGCCGAGCACGGCATCATCGTCGAGAAGACCGGGCTGTACTCGTTCTTCATCATGTT
CACCATCGGCATCACCAAGGGCCGCTGGAACTCGATGGTGACCGAGCTGCAGCAGTTCAAGGACGACTACGACAACAACC
AGCCGCTGTGGCGCGTGCTGCCGGAGTTCGTGCGGCAGTATCCGCAATACGAGCGCATCGGCCTGCGCGAGCTGTGCGAC
GCCATCCACAGCGTCTACAAGGCCAACGACGTGGCCCGCGTGACCACCGAGATGTACCTCTCCAACATGGAGCCGGCGAT
GAAGCCGTCGGACGCATGGGCCAAGATGGCGCACCGCGAGACCGAGCGCGTGGCCATCGACGACCTGGAGGGCCGCATCA
CCGCCATCCTGCTGACGCCGTATCCGCCGGGCATTCCGCTGCTGATCCCGGGCGAGCGCTTCAACCGGACCATCGTGCAG
TACCTGCAGTTCGCGCGCGAGTTCAACAAGCTGTTCCCGGGCTTCGAGACCGATATCCACGGGCTGGTGGAGGAGGAGAT
TGAGGGTCGGGTTGGGTACTTTGTCGACTGCGTGAGGTGA

Upstream 100 bases:

>100_bases
CCAGGGCCAGCACGGCGTGACGCTGCCCAAAACCTAGTTTCAGTTGTCCGTTTCCGCGATCCGGAGCGGTGCCTTTTGTT
TCATCAGTCAAGGAATCCCG

Downstream 100 bases:

>100_bases
TTGCCGCAACAGGGGCGCACGAGTCGTCGTGCGCCGACTGTACGAGCAGATGAGCAAGCCCGGCCAAGTGCCGGGCTTTT
TCATGTCCGGTGACGCGACG

Product: biodegradative arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MKFRFPVIIIDEDFRSENISGSGIRALAQAIEEEGMEVTGLTSYGDLTSFAQQSSRASTFIVSIDDDEFINPDNDKPEPE
AVENLRSFVAEVRRRNANIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREARNYLDSLPPPFFKALID
YAQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFGSDHMFFVTN
GTSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPQSEFEPETIARKIAEHPFASQA
ANKKPRILTLTQGTYDGVLYNAERIKHMLSTEIDTLHFDEAWLPHASFHPFYRDMHAIGQGRARSKDALVFATQSTHKLL
AGLSQASQILVQDSETRKLDTYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIAEALDFRRAMRKVEQE
YVGTNGGNGRGDDWWFKVWGPNDLSDEGIEEREAWMLKANERWHGFGDLAEDFNLLDPIKATIITPGLDVDGKFSESGIP
AAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVRQYPQYERIGLRELCD
AIHSVYKANDVARVTTEMYLSNMEPAMKPSDAWAKMAHRETERVAIDDLEGRITAILLTPYPPGIPLLIPGERFNRTIVQ
YLQFAREFNKLFPGFETDIHGLVEEEIEGRVGYFVDCVR

Sequences:

>Translated_759_residues
MKFRFPVIIIDEDFRSENISGSGIRALAQAIEEEGMEVTGLTSYGDLTSFAQQSSRASTFIVSIDDDEFINPDNDKPEPE
AVENLRSFVAEVRRRNANIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREARNYLDSLPPPFFKALID
YAQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFGSDHMFFVTN
GTSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPQSEFEPETIARKIAEHPFASQA
ANKKPRILTLTQGTYDGVLYNAERIKHMLSTEIDTLHFDEAWLPHASFHPFYRDMHAIGQGRARSKDALVFATQSTHKLL
AGLSQASQILVQDSETRKLDTYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIAEALDFRRAMRKVEQE
YVGTNGGNGRGDDWWFKVWGPNDLSDEGIEEREAWMLKANERWHGFGDLAEDFNLLDPIKATIITPGLDVDGKFSESGIP
AAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVRQYPQYERIGLRELCD
AIHSVYKANDVARVTTEMYLSNMEPAMKPSDAWAKMAHRETERVAIDDLEGRITAILLTPYPPGIPLLIPGERFNRTIVQ
YLQFAREFNKLFPGFETDIHGLVEEEIEGRVGYFVDCVR
>Mature_759_residues
MKFRFPVIIIDEDFRSENISGSGIRALAQAIEEEGMEVTGLTSYGDLTSFAQQSSRASTFIVSIDDDEFINPDNDKPEPE
AVENLRSFVAEVRRRNANIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIREARNYLDSLPPPFFKALID
YAQDSSYSWHCPGHSGGVAFLKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFGSDHMFFVTN
GTSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPQSEFEPETIARKIAEHPFASQA
ANKKPRILTLTQGTYDGVLYNAERIKHMLSTEIDTLHFDEAWLPHASFHPFYRDMHAIGQGRARSKDALVFATQSTHKLL
AGLSQASQILVQDSETRKLDTYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIAEALDFRRAMRKVEQE
YVGTNGGNGRGDDWWFKVWGPNDLSDEGIEEREAWMLKANERWHGFGDLAEDFNLLDPIKATIITPGLDVDGKFSESGIP
AAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVRQYPQYERIGLRELCD
AIHSVYKANDVARVTTEMYLSNMEPAMKPSDAWAKMAHRETERVAIDDLEGRITAILLTPYPPGIPLLIPGERFNRTIVQ
YLQFAREFNKLFPGFETDIHGLVEEEIEGRVGYFVDCVR

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=774, Percent_Identity=38.3720930232558, Blast_Score=552, Evalue=1e-158,
Organism=Escherichia coli, GI1790573, Length=722, Percent_Identity=38.3656509695291, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1786384, Length=727, Percent_Identity=37.2764786795048, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1786909, Length=677, Percent_Identity=33.0871491875923, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI87082193, Length=677, Percent_Identity=32.6440177252585, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85710; Mature: 85710

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAQAIEEEGMEVTGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFINPDNDKPEPEAVENLRSFVAEVRRRNANIPIFLYGETRTSRHLPNDILRE
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHH
LHGFIHMFEDTPEFVARHIIREARNYLDSLPPPFFKALIDYAQDSSYSWHCPGHSGGVAF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHH
LKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFGSDHMFFVTN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEC
GTSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPQS
CCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCC
EFEPETIARKIAEHPFASQAANKKPRILTLTQGTYDGVLYNAERIKHMLSTEIDTLHFDE
CCCHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCCEEECHHHHHHHHHHCCCEEECCC
AWLPHASFHPFYRDMHAIGQGRARSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLD
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEEECCCCCCCC
TYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIAEALDFRRAMRKVEQE
CEEECCEEEEEECCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YVGTNGGNGRGDDWWFKVWGPNDLSDEGIEEREAWMLKANERWHGFGDLAEDFNLLDPIK
HCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHEEEECCCCCCCCCCHHHHCCCCCCCH
ATIITPGLDVDGKFSESGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMV
HEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHH
TELQQFKDDYDNNQPLWRVLPEFVRQYPQYERIGLRELCDAIHSVYKANDVARVTTEMYL
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SNMEPAMKPSDAWAKMAHRETERVAIDDLEGRITAILLTPYPPGIPLLIPGERFNRTIVQ
HCCCCCCCCCHHHHHHHHHHHHHEEHCCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHH
YLQFAREFNKLFPGFETDIHGLVEEEIEGRVGYFVDCVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MKFRFPVIIIDEDFRSENISGSGIRALAQAIEEEGMEVTGLTSYGDLTSFAQQSSRASTF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
IVSIDDDEFINPDNDKPEPEAVENLRSFVAEVRRRNANIPIFLYGETRTSRHLPNDILRE
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHH
LHGFIHMFEDTPEFVARHIIREARNYLDSLPPPFFKALIDYAQDSSYSWHCPGHSGGVAF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHH
LKSPVGQVFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFGSDHMFFVTN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEC
GTSTSNKMVWHANVAPGDIVVVDRNCHKSILHAIMMTGAIPVFLMPTRNHYGIIGPIPQS
CCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCC
EFEPETIARKIAEHPFASQAANKKPRILTLTQGTYDGVLYNAERIKHMLSTEIDTLHFDE
CCCHHHHHHHHHHCCCHHHHCCCCCCEEEEECCCCCCEEECHHHHHHHHHHCCCEEECCC
AWLPHASFHPFYRDMHAIGQGRARSKDALVFATQSTHKLLAGLSQASQILVQDSETRKLD
CCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHEEEECCCCCCCC
TYRFNEAYLMHTSTSPQYSIIASCDVAAAMMEAPGGTALVEESIAEALDFRRAMRKVEQE
CEEECCEEEEEECCCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YVGTNGGNGRGDDWWFKVWGPNDLSDEGIEEREAWMLKANERWHGFGDLAEDFNLLDPIK
HCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHEEEECCCCCCCCCCHHHHCCCCCCCH
ATIITPGLDVDGKFSESGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMV
HEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHH
TELQQFKDDYDNNQPLWRVLPEFVRQYPQYERIGLRELCDAIHSVYKANDVARVTTEMYL
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SNMEPAMKPSDAWAKMAHRETERVAIDDLEGRITAILLTPYPPGIPLLIPGERFNRTIVQ
HCCCCCCCCCHHHHHHHHHHHHHEEHCCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHH
YLQFAREFNKLFPGFETDIHGLVEEEIEGRVGYFVDCVR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]