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The map label for this gene is ttuB [H]

Identifier: 17547071

GI number: 17547071

Start: 2551345

End: 2552673

Strand: Direct

Name: ttuB [H]

Synonym: RSc2352

Alternate gene names: 17547071

Gene position: 2551345-2552673 (Clockwise)

Preceding gene: 17547070

Following gene: 17547072

Centisome position: 68.65

GC content: 68.55

Gene sequence:

>1329_bases
ATGGCCACCACCACCCCGCCTCTCGGCCCGAGCGCCGGCGCGCTGCCGCCCCAGTCCGCCAGCGGCTTCGAGGAAGCCAC
GTACCGCAAGGTCAGCTGGCGCCTGATCCCCTTTCTGCTGCTGTGCTACGTGGTCGCCTACCTGGACCGGGTCAACGTCG
GCTTCGCCAAGCTGCAGATGCTGAACGATCTCAAGTTCAGCGAGACCGTGTACGGGCTGGGCGCGGGCATCTTCTTCATC
GGCTACTTCCTCTTCGAGGTGCCCAGCAATGTGATCCTGCATCGGGTCGGCGCGCGGATGTGGATCGCGCGGATCATGAT
CTCGTGGGGCCTCATCTCCGCGGCCATGATGTTCGTGACCACGCCGGCCATGTTCTACGTGATGCGCTTCCTGCTCGGCC
TGGCCGAGGCGGGCTTCTTCCCGGGCATCATCCTGTACCTCACGTACTGGTATCCGGCCGAGCGGCGCGGGCGCACCACC
ACGTTCTTCATGACGGCCGTGGCGCTGTCGGGCGTGATCGGCGGCCCCATCTCGGGCTGGGCGCTCAAGACGTTCGGGGG
CGTCTACGGCCTGGCCGGCTGGCAGTGGATGTTCCTCATCGAGGGCATCCCGTCGGTCGTCATCGGGCTGTGCGTGCTGG
CCTACCTGGACAATCGCATCAGCCACGCCAGGTGGCTGACCGACGAGGAAAAGGCCCTGCTCACCCGCAACATCGCGGCC
GAGGAGGCGCAGAAGGAAGACGCGCCCATCGCCGCCATCATGGCCAGCCCGCGCGTCTGGCTGATGAGCCTGATCTACTT
CAGCTTCGTGATGGGCCTGTACGGGGTGAGCTTCTGGCTGCCGACGCTGATCAAGCAGACCGGCGTGGCCGATCCGCTGT
CGGTGGGCCTGCTGACGGCGATCCCGTACGGCGCGGCGGTGGTCGCCATGGTGCTGGTCGCCCGCAGCGCCGACCGCACG
CGCGAGCGCCGCTGGCACATTGCCATCCCGGCCCTCGCGGGCGCGATCGGGCTGGTGCTCTCGGCGGTCTGGCACACCAA
CACCACGCTGGCCATGGCGGCGCTGACGCTCGGCACCATGGGCATCCTGACCACGCTGCCGCTGTTCTGGAGCCTGCCGA
CCGCCTTCCTGGCCGGCACCGGCGCCGCCGCCGGCATCGCGCTGATCAATTCGCTGGGCAACCTGGCCGGCTTCCTGAGC
CCCTACGCCGTGGGCTGGCTGAAGGACACCACCCGGAGCACCGACTCGGGCATGTACCTGCTGGCGGCGTCGATGGTGCT
GGGCGCGCTGCTGACCCTGTCGGTGCCCGCGCGGACGGTCAACCGGTAG

Upstream 100 bases:

>100_bases
CGGTGGCGGTTCGATCGGGTCGGCCGGAAGCCTGCGGCGCGGGCGCGCTGGAGGGGCAGAGCCGCAACCGGCCCGCATAC
AAAACAAGACAGGAGACCCG

Downstream 100 bases:

>100_bases
CCGCATCGCGAACCTCGCCGAGCGGGCCCGCCGCACGGCGATTCTTGCGATGGCCTTTGAGCGGGCCGCGCCATGGCCCG
CGCCGTATTGCGAACCATTC

Product: permease transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MATTTPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFI
GYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTT
TFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAA
EEAQKEDAPIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRT
RERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLS
PYAVGWLKDTTRSTDSGMYLLAASMVLGALLTLSVPARTVNR

Sequences:

>Translated_442_residues
MATTTPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFI
GYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTT
TFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAA
EEAQKEDAPIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRT
RERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLS
PYAVGWLKDTTRSTDSGMYLLAASMVLGALLTLSVPARTVNR
>Mature_441_residues
ATTTPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIG
YFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTT
FFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAE
EAQKEDAPIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTR
ERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSP
YAVGWLKDTTRSTDSGMYLLAASMVLGALLTLSVPARTVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=24.1025641025641, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=38.1861575178998, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789515, Length=444, Percent_Identity=22.972972972973, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI2367379, Length=462, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=23.1818181818182, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=20.8920187793427, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=346, Percent_Identity=24.5664739884393, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322025, Length=190, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6319876, Length=321, Percent_Identity=25.2336448598131, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321502, Length=375, Percent_Identity=24.8, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=294, Percent_Identity=25.1700680272109, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=340, Percent_Identity=22.9411764705882, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=214, Percent_Identity=26.6355140186916, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24584153, Length=361, Percent_Identity=24.0997229916898, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641682, Length=395, Percent_Identity=24.8101265822785, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639764, Length=429, Percent_Identity=21.9114219114219, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654215, Length=348, Percent_Identity=24.4252873563218, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922400, Length=348, Percent_Identity=24.4252873563218, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=364, Percent_Identity=22.5274725274725, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47839; Mature: 47708

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
ATTTPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQM
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH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HHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]