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The map label for this gene is yezC [H]

Identifier: 17547037

GI number: 17547037

Start: 2518321

End: 2518776

Strand: Direct

Name: yezC [H]

Synonym: RSc2318

Alternate gene names: 17547037

Gene position: 2518321-2518776 (Clockwise)

Preceding gene: 17547034

Following gene: 17547038

Centisome position: 67.76

GC content: 58.11

Gene sequence:

>456_bases
ATGAAACCTAAGGCGGTGGAGCTGGATCGACTCGACTGGCGCATTCTCGAGGTGCTACAAACGCATGCGCGCGTGACGAA
TACCGAGCTGGGCAAGCAGATTGGATTGTCGCAGCCGGCTGTCAGCGCCCGGATCAGGCGACTAGAGGAGCAAGGCGTGA
TCGAAGGCTACTCGGCAAGAATCAACCCCGAGCTGGCCGGTCGTGACATCTCCGCGCTAATCCGTATACAAACGACTCAC
GCGCAGATCACGAAGTGCCTGAAGGCCTTCGCGACGATGCCTGAGATCATCGAGGCACACCGGATCACGGGCGACGATTG
CTTCATTGTGCGTGCGGTAGTCCAAAGAATGAAGCAGCTCGAAACCGTCGTCGACGCGCTGGCCAGATTTGGACCTGTGA
CGACCTCGATCGTATTGGCAAGCTATCCGCCCAAGGCGATTGGCGAAATCAGGTAG

Upstream 100 bases:

>100_bases
AGCATCCAGTGTAAAAGCCGATGCGCTCTGTCAGAATGGCTGAGCCATTGAAATCAATGCCAACTGGCTTCGAATACACG
GAATTGAAGGGCTTAAACGA

Downstream 100 bases:

>100_bases
TCGATCCTGAGCAATCCGCAGACCAACAGGGACAAGAGCGATACGTCCAGCGAATCAGCAGGTCCGATCTCGACAAATGA
ATCGCCCATTGCGAACACAA

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKPKAVELDRLDWRILEVLQTHARVTNTELGKQIGLSQPAVSARIRRLEEQGVIEGYSARINPELAGRDISALIRIQTTH
AQITKCLKAFATMPEIIEAHRITGDDCFIVRAVVQRMKQLETVVDALARFGPVTTSIVLASYPPKAIGEIR

Sequences:

>Translated_151_residues
MKPKAVELDRLDWRILEVLQTHARVTNTELGKQIGLSQPAVSARIRRLEEQGVIEGYSARINPELAGRDISALIRIQTTH
AQITKCLKAFATMPEIIEAHRITGDDCFIVRAVVQRMKQLETVVDALARFGPVTTSIVLASYPPKAIGEIR
>Mature_151_residues
MKPKAVELDRLDWRILEVLQTHARVTNTELGKQIGLSQPAVSARIRRLEEQGVIEGYSARINPELAGRDISALIRIQTTH
AQITKCLKAFATMPEIIEAHRITGDDCFIVRAVVQRMKQLETVVDALARFGPVTTSIVLASYPPKAIGEIR

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=116, Percent_Identity=37.0689655172414, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16811; Mature: 16811

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKAVELDRLDWRILEVLQTHARVTNTELGKQIGLSQPAVSARIRRLEEQGVIEGYSAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
INPELAGRDISALIRIQTTHAQITKCLKAFATMPEIIEAHRITGDDCFIVRAVVQRMKQL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ETVVDALARFGPVTTSIVLASYPPKAIGEIR
HHHHHHHHHCCCHHHHHEEECCCCHHCCCCC
>Mature Secondary Structure
MKPKAVELDRLDWRILEVLQTHARVTNTELGKQIGLSQPAVSARIRRLEEQGVIEGYSAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
INPELAGRDISALIRIQTTHAQITKCLKAFATMPEIIEAHRITGDDCFIVRAVVQRMKQL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ETVVDALARFGPVTTSIVLASYPPKAIGEIR
HHHHHHHHHCCCHHHHHEEECCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]