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The map label for this gene is pgi [H]

Identifier: 17546856

GI number: 17546856

Start: 2318039

End: 2318503

Strand: Direct

Name: pgi [H]

Synonym: RSc2137

Alternate gene names: 17546856

Gene position: 2318039-2318503 (Clockwise)

Preceding gene: 17546855

Following gene: 17546857

Centisome position: 62.37

GC content: 67.53

Gene sequence:

>465_bases
TTGATCGACATGCCCACCGCCCTTCCCGCCCGGCAGTCCCTGTCGCAACATGCCCAAGCGATCCGCGCCACCCACATGCG
TGATTGGTTTGCCGCACCGGACGCCGAGCAACGGGTGCACGCCTTCACCGTGGAAGCCGCCGGGCTCACGCTCGACTACG
CCAAGAACCGCATCCCCCCCGAAACGCTCGCGCTGCCGCTCCAGCTCGCAGACGAAGCCGGCGTCCTCGCGCTGCGCGAT
GCCATGCTGCGCGGCGAGCGCATCAACAACACTGAGCACCGCACCTTCGTGCAGGGTGCGGTCTGGAACATCAACTCGTT
CGACCAATGGGGCGTCGAACTCGGCAAGAAGCTCGCCAAGCCGATCCTCGAAGAACTGGAAGGCGCGCCGGCCTCGGTGG
CGCCCGACACCTCGACGGCGGCGCTGATCCGCCGCGCCAGGCGCGATCCGTGCAACCCAGCTTAA

Upstream 100 bases:

>100_bases
GCATCGCAGGCGATGTCACCGATCCATCGGCGACGGCCGCGAAGGCTGAGTGTGTTGAAGCCGTAGCCCTTCCCTATTGA
TAACGCGACCGCCCATCCGC

Downstream 100 bases:

>100_bases
CCGCGCATTGCGATGGATTTGGCCATGGAAACAAAAAGTCGGGCATTGACAACTGCGGCGGCACAGGAAAAGCCGGTGTG
CGGGATCGTGGACGATCCGT

Product: hypothetical protein

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIDMPTALPARQSLSQHAQAIRATHMRDWFAAPDAEQRVHAFTVEAAGLTLDYAKNRIPPETLALPLQLADEAGVLALRD
AMLRGERINNTEHRTFVQGAVWNINSFDQWGVELGKKLAKPILEELEGAPASVAPDTSTAALIRRARRDPCNPA

Sequences:

>Translated_154_residues
MIDMPTALPARQSLSQHAQAIRATHMRDWFAAPDAEQRVHAFTVEAAGLTLDYAKNRIPPETLALPLQLADEAGVLALRD
AMLRGERINNTEHRTFVQGAVWNINSFDQWGVELGKKLAKPILEELEGAPASVAPDTSTAALIRRARRDPCNPA
>Mature_154_residues
MIDMPTALPARQSLSQHAQAIRATHMRDWFAAPDAEQRVHAFTVEAAGLTLDYAKNRIPPETLALPLQLADEAGVLALRD
AMLRGERINNTEHRTFVQGAVWNINSFDQWGVELGKKLAKPILEELEGAPASVAPDTSTAALIRRARRDPCNPA

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI296080693, Length=62, Percent_Identity=53.2258064516129, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI18201905, Length=67, Percent_Identity=49.2537313432836, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996708, Length=59, Percent_Identity=54.2372881355932, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996703, Length=59, Percent_Identity=54.2372881355932, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319673, Length=61, Percent_Identity=55.7377049180328, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651916, Length=59, Percent_Identity=55.9322033898305, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24651914, Length=59, Percent_Identity=55.9322033898305, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737445, Length=59, Percent_Identity=55.9322033898305, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 16914; Mature: 16914

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDMPTALPARQSLSQHAQAIRATHMRDWFAAPDAEQRVHAFTVEAAGLTLDYAKNRIPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEHHCCEEHHHHHCCCCH
ETLALPLQLADEAGVLALRDAMLRGERINNTEHRTFVQGAVWNINSFDQWGVELGKKLAK
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PILEELEGAPASVAPDTSTAALIRRARRDPCNPA
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIDMPTALPARQSLSQHAQAIRATHMRDWFAAPDAEQRVHAFTVEAAGLTLDYAKNRIPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEHHCCEEHHHHHCCCCH
ETLALPLQLADEAGVLALRDAMLRGERINNTEHRTFVQGAVWNINSFDQWGVELGKKLAK
HHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
PILEELEGAPASVAPDTSTAALIRRARRDPCNPA
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA