Click here to switch to the map view.

The map label for this gene is uxuR [H]

Identifier: 17546821

GI number: 17546821

Start: 2277606

End: 2278370

Strand: Direct

Name: uxuR [H]

Synonym: RSc2102

Alternate gene names: 17546821

Gene position: 2277606-2278370 (Clockwise)

Preceding gene: 17546820

Following gene: 17546822

Centisome position: 61.29

GC content: 67.32

Gene sequence:

>765_bases
ATGCTCAGCATTCCATCCTCCGTTGCACAAGCGCTCCAGCAACGCATCATGAGCGGCGATTACGCCAGTGGCACCCGGCT
GCCGCCGCAGCGTGAACTGGCGGCAAGCCTGGGGGTGAGCCGCGCCTCGCTGCGCGAAGCCCTGACCGTGCTGGAAACGC
TTGGCCTCGTAGACATCCTGCCGAGCAAGGGTGTGGTGGTGCGCGGCCCGCACGCGGATGCCGAGCGCATGCACCGCCCA
TTCGCCACGCCGGCGCTCGGCACGCTGTCGCCGCGTCAACTGATTGAGTTGCGCCTGGTGCTGGAGCCCGGCTGGACAGC
GCTGGCCGCGACTCGCATGCATGCCGCCGGCCTGCGTCAATTGCAGTGGCTGCAGAAGCAGCTTGCCCATGCGCTGGAGC
GCAACGACCTGCTCAGCGCGGCCGAGGCCGACTTGCAGTTCCACCTGCTGCTGGCCGAGTTGTCAGGCAACCCGGGCCTG
GTTGCGATGGCGGGCCAACTGGAGCACGCCATTGGCCACAGCCTGCGCCTGCCCTTTGCCAAGAACGGCGCAGACGACCA
GCCCGCGCGCGAGCACGACGCCATCGTGCAGGCCATTGGCGCGGGTGATGCCACCGCCAGCGCAGAAGCCATGCGCGCCC
ATTTGATGTCGGCCGCGCGCCGCAGCGGTATTGACCTGGCCACGCCGGTCCCCGCACCAGACCGCACGCACAACAATCCT
GTTTCCTTTCGCTTCGACCCGACTTCTGAAGGAGTTCTTGAATGA

Upstream 100 bases:

>100_bases
CCACAGCGCCAAGACGCCGTTTTTGTTGCTTGGCACAAAACTCGCATATGCCGTGGGCGACCGGTCAGACCACGACCGAG
TCTTTCCCTCTTTCAGGCCC

Downstream 100 bases:

>100_bases
CCCGCTTGCTCACCCGCCGCACATTCATCCACGCCATGCTGGCGGCCAGCGCCGTGGCCGCCTTGTTGCCGGGCCGTCCG
GCCCATGCCGATGCGCTGGC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLSIPSSVAQALQQRIMSGDYASGTRLPPQRELAASLGVSRASLREALTVLETLGLVDILPSKGVVVRGPHADAERMHRP
FATPALGTLSPRQLIELRLVLEPGWTALAATRMHAAGLRQLQWLQKQLAHALERNDLLSAAEADLQFHLLLAELSGNPGL
VAMAGQLEHAIGHSLRLPFAKNGADDQPAREHDAIVQAIGAGDATASAEAMRAHLMSAARRSGIDLATPVPAPDRTHNNP
VSFRFDPTSEGVLE

Sequences:

>Translated_254_residues
MLSIPSSVAQALQQRIMSGDYASGTRLPPQRELAASLGVSRASLREALTVLETLGLVDILPSKGVVVRGPHADAERMHRP
FATPALGTLSPRQLIELRLVLEPGWTALAATRMHAAGLRQLQWLQKQLAHALERNDLLSAAEADLQFHLLLAELSGNPGL
VAMAGQLEHAIGHSLRLPFAKNGADDQPAREHDAIVQAIGAGDATASAEAMRAHLMSAARRSGIDLATPVPAPDRTHNNP
VSFRFDPTSEGVLE
>Mature_254_residues
MLSIPSSVAQALQQRIMSGDYASGTRLPPQRELAASLGVSRASLREALTVLETLGLVDILPSKGVVVRGPHADAERMHRP
FATPALGTLSPRQLIELRLVLEPGWTALAATRMHAAGLRQLQWLQKQLAHALERNDLLSAAEADLQFHLLLAELSGNPGL
VAMAGQLEHAIGHSLRLPFAKNGADDQPAREHDAIVQAIGAGDATASAEAMRAHLMSAARRSGIDLATPVPAPDRTHNNP
VSFRFDPTSEGVLE

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994961, Length=215, Percent_Identity=32.093023255814, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790780, Length=219, Percent_Identity=31.5068493150685, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082208, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790032, Length=221, Percent_Identity=31.2217194570136, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=31.4410480349345, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789353, Length=211, Percent_Identity=29.3838862559242, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27094; Mature: 27094

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIPSSVAQALQQRIMSGDYASGTRLPPQRELAASLGVSRASLREALTVLETLGLVDIL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PSKGVVVRGPHADAERMHRPFATPALGTLSPRQLIELRLVLEPGWTALAATRMHAAGLRQ
CCCCEEEECCCCCHHHHHCCCCCCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHH
LQWLQKQLAHALERNDLLSAAEADLQFHLLLAELSGNPGLVAMAGQLEHAIGHSLRLPFA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEECCCC
KNGADDQPAREHDAIVQAIGAGDATASAEAMRAHLMSAARRSGIDLATPVPAPDRTHNNP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VSFRFDPTSEGVLE
EEEEECCCCCCCCC
>Mature Secondary Structure
MLSIPSSVAQALQQRIMSGDYASGTRLPPQRELAASLGVSRASLREALTVLETLGLVDIL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PSKGVVVRGPHADAERMHRPFATPALGTLSPRQLIELRLVLEPGWTALAATRMHAAGLRQ
CCCCEEEECCCCCHHHHHCCCCCCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHH
LQWLQKQLAHALERNDLLSAAEADLQFHLLLAELSGNPGLVAMAGQLEHAIGHSLRLPFA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEECCCC
KNGADDQPAREHDAIVQAIGAGDATASAEAMRAHLMSAARRSGIDLATPVPAPDRTHNNP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VSFRFDPTSEGVLE
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]