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The map label for this gene is nuoC [H]

Identifier: 17546779

GI number: 17546779

Start: 2234483

End: 2235085

Strand: Reverse

Name: nuoC [H]

Synonym: RSc2060

Alternate gene names: 17546779

Gene position: 2235085-2234483 (Counterclockwise)

Preceding gene: 17546780

Following gene: 17546778

Centisome position: 60.14

GC content: 64.51

Gene sequence:

>603_bases
ATGACCGACAAGCTTGCCACCCTGCAGTCCGCGCTCGAAAAGGCGCTGGGCAATCGCATCCAGAGCCTGACCGAGGCGGT
CGGTGAAATCACGCTCGTGGTGAAGGCGGCCGATTACCTGGAAACCATGCGCACGCTGCGCGACGATGCCACGCTCAAGT
TCGAGCAGCTGATCGATCTGTGCGGCGTGGACTATTCCGCCTACGGCGACGGTGCCTGGAACGGCCCGCGCTTTGCCGCC
GTGTCGCACCTGCTGTCGGTCACGCACAACTGGCGCGTGCGCGTGCGCGTGTTCGCGCCGGACGATGATCTTCCCGTCGT
GGCGTCCGTGGTCGATGTCTGGAACGCCGCCGACTGGTTCGAGCGCGAGGCGTTCGACCTGTATGGGCTGGTCTTCGAAG
GCCACCCGGACCTGCGCCGCATCCTGACCGACTACGGCTTCATCGGCCACCCGTTCCGCAAGGATTTTCCGGTGTCGGGC
TATGTGGAAATGCGTTACGACCCCGTGCAGCGCCGCGTGATCTACCAGCCGGTGACCATCGAGCCGCGCGAGATTACGCC
GCGTGTGATCCGCGAGGATCAATACGGTGGCCTGAAGCACTGA

Upstream 100 bases:

>100_bases
GTGCCGGGCTGCCCGCCGACAGCCGAAGCGCTGATCTACGGCATCATCCAGCTGCAGGCGAAGATCCGCCGTACCAACAC
CATCGCGCGCAAGGGCTGAC

Downstream 100 bases:

>100_bases
AGGGCGCCTGATCATGGCTGACATCAAGAACTACACCCTCAACTTCGGCCCGCAGCACCCGGCCGCGCACGGCGTGCTGC
GTCTGGTGCTGGAGCTGGAT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTDKLATLQSALEKALGNRIQSLTEAVGEITLVVKAADYLETMRTLRDDATLKFEQLIDLCGVDYSAYGDGAWNGPRFAA
VSHLLSVTHNWRVRVRVFAPDDDLPVVASVVDVWNAADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPVQRRVIYQPVTIEPREITPRVIREDQYGGLKH

Sequences:

>Translated_200_residues
MTDKLATLQSALEKALGNRIQSLTEAVGEITLVVKAADYLETMRTLRDDATLKFEQLIDLCGVDYSAYGDGAWNGPRFAA
VSHLLSVTHNWRVRVRVFAPDDDLPVVASVVDVWNAADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPVQRRVIYQPVTIEPREITPRVIREDQYGGLKH
>Mature_199_residues
TDKLATLQSALEKALGNRIQSLTEAVGEITLVVKAADYLETMRTLRDDATLKFEQLIDLCGVDYSAYGDGAWNGPRFAAV
SHLLSVTHNWRVRVRVFAPDDDLPVVASVVDVWNAADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGY
VEMRYDPVQRRVIYQPVTIEPREITPRVIREDQYGGLKH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=160, Percent_Identity=43.125, Blast_Score=137, Evalue=8e-33,
Organism=Escherichia coli, GI145693162, Length=109, Percent_Identity=32.1100917431193, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990788, Length=176, Percent_Identity=39.7727272727273, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563621, Length=176, Percent_Identity=39.7727272727273, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24656494, Length=168, Percent_Identity=39.8809523809524, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22831; Mature: 22700

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKLATLQSALEKALGNRIQSLTEAVGEITLVVKAADYLETMRTLRDDATLKFEQLIDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCHHHHHHHHH
CGVDYSAYGDGAWNGPRFAAVSHLLSVTHNWRVRVRVFAPDDDLPVVASVVDVWNAADWF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHH
EREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPVQRRVIYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHEEECCCCC
EPREITPRVIREDQYGGLKH
CCHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDKLATLQSALEKALGNRIQSLTEAVGEITLVVKAADYLETMRTLRDDATLKFEQLIDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHCCCCHHHHHHHHH
CGVDYSAYGDGAWNGPRFAAVSHLLSVTHNWRVRVRVFAPDDDLPVVASVVDVWNAADWF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHH
EREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPVQRRVIYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHEEECCCCC
EPREITPRVIREDQYGGLKH
CCHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA