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The map label for this gene is dppA2 [H]

Identifier: 17546605

GI number: 17546605

Start: 2069903

End: 2071480

Strand: Direct

Name: dppA2 [H]

Synonym: RSc1886

Alternate gene names: 17546605

Gene position: 2069903-2071480 (Clockwise)

Preceding gene: 17546604

Following gene: 17546606

Centisome position: 55.7

GC content: 67.93

Gene sequence:

>1578_bases
GTGAAACGCCTCCTTGCCTCTTCGCTGGCCGTTGCCCTGCTGGCCGCCGCCGCACTCCCGGGCCCTGCCGGCGCCCAGAC
GCTCAGCATCGGCTTTGCCGATCCGCTGTCGTCGCTCGACCCGCAGCTCAACAACCACGCCGGCGACCGCTCGGTCGACG
TGCACTTCTGGGACCTGCTGGTCGAGAACAAGTGGAACCGGCTGCAGCCCGGCCTGGCGCTGGCGTGGAAGCCGCTGGAC
CCGAAGACGTGGGAGTTCAAGCTGCGCCCCGGCGTGAAATGGCAGGACGGCAAGCCCTTCACCGCCGACGACGTCATCTT
CTCGTACCAGCGCGCGCGCAGCGTGCCGGGCAGCGTGGCGACCTTCGCGGGCTACCTGCGCACGGTCGAGTCGGTCAGCG
CCAAGGACCCGCTCACGCTCATCGTCAAGACCACGATCCCCAACCCCGACCTGCCGCTGAACCTGGCCTCGGTGCACATC
GTCAGCAAGCACATCGGCGAGAAGTCGAACACCGAGGACTACAACGCCGGCCGCGCCGTGGTCGGCACCGGTCCGTTCAA
GTTCGTCGCGTACACACCGGGCGAGCGCGTGGTGATGGCGCGCAACGATGCCTACTGGGGCGGCAAATCGCCGTGGGAGA
AGGTCAACTACCGCTACATCAACAACGCCGCCGCGCGCACCGCCAACCTGCTGTCGGGCGAGGTGGACGTGATCGACAAG
GTCTCGGTGGCCGACCTCGCGCGGCTGCGCCAGTCGCCCGGCGTCAAGGTGTACGCCTACCCCGGCCTGCGCGTGATGCT
GCTGCAGCCGAGCTTCCGCCAGGGCCCGAACGAATACCTCACCGGCAACGACGGCAAGCCGCTGCCGAACAACCCGCTGC
TGGACGTGCGCGTGCGCCGCGCGCTGTCGCTGGCAATCGACCGCAGGGCCATCGTCGACCGCATCCTGCAGGGCGCCGCC
ACGGTCGCCAACCAGTGGATGCCGGCCGACACCTTCGGCTACAACCCCGAGGTGAAGGACATTGCCTACGACCCGGCGCA
GGCCAGGAAGCTGCTGGCCGAGGCCGGCTTTGCGCAGGGCTTCAACCTGGTGATGCACGTGCCGAACGACCGCTACCCGC
AGGGCCCGGAAACGGCGCAGGCGGTGGCGCAGTTCTGGACGCGCATCGGCGTGAAAGCCAAGGTGGAAGTGGTGCCGTGG
TCGGTCTATGCCAGCCGCGCCAACAAGAACGACTATGCGATGAGCATGCTGGCCTGGGGCAACGGCACCGGCGAGGCCAG
CTACGCGCTGGTCAACGTGCTGGCCACGGTCGATGCCAAGAAGGGCCTGGGCGCCTCCAACTGGGGCCACTACAGCAACC
AGGCGGTGGACCATGCGCTGGACGCTTCCACCGAGGAGTTCAACACCGAGAAGCGCGCCGCCATCCTGCGCCACTCGGTC
AAGGTGGTCTCGGACGACGTGGGTGTGCTGCCGCTGTACCACTACCAGAACGTCTGGGCCGCGAAGAAGGGCCTGAAGGT
GACGCCGATGACCAGCGACCGCACCGCGGCCATGATGGTCACGCAGGACGGCAAGTAA

Upstream 100 bases:

>100_bases
CCGACGCTGCGCGGCATTGCCGTCAACCATGTCAGCGCGTGCCACCTGAACGACGGCCGCTAAGCCGCACCCACCCAGAA
CATCAACAACAGGACCGAAC

Downstream 100 bases:

>100_bases
GCGCGCCGTGGCCGCTTCGCCCGCCTTTGCGCTCAGCGTCGCACCGGCCGACGACCTGATCGACGTGCCGCGCCGCATCG
TCGTGACGGGGCTGGTGCCC

Product: periplasmic dipeptide transport protein precursor

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKRLLASSLAVALLAAAALPGPAGAQTLSIGFADPLSSLDPQLNNHAGDRSVDVHFWDLLVENKWNRLQPGLALAWKPLD
PKTWEFKLRPGVKWQDGKPFTADDVIFSYQRARSVPGSVATFAGYLRTVESVSAKDPLTLIVKTTIPNPDLPLNLASVHI
VSKHIGEKSNTEDYNAGRAVVGTGPFKFVAYTPGERVVMARNDAYWGGKSPWEKVNYRYINNAAARTANLLSGEVDVIDK
VSVADLARLRQSPGVKVYAYPGLRVMLLQPSFRQGPNEYLTGNDGKPLPNNPLLDVRVRRALSLAIDRRAIVDRILQGAA
TVANQWMPADTFGYNPEVKDIAYDPAQARKLLAEAGFAQGFNLVMHVPNDRYPQGPETAQAVAQFWTRIGVKAKVEVVPW
SVYASRANKNDYAMSMLAWGNGTGEASYALVNVLATVDAKKGLGASNWGHYSNQAVDHALDASTEEFNTEKRAAILRHSV
KVVSDDVGVLPLYHYQNVWAAKKGLKVTPMTSDRTAAMMVTQDGK

Sequences:

>Translated_525_residues
MKRLLASSLAVALLAAAALPGPAGAQTLSIGFADPLSSLDPQLNNHAGDRSVDVHFWDLLVENKWNRLQPGLALAWKPLD
PKTWEFKLRPGVKWQDGKPFTADDVIFSYQRARSVPGSVATFAGYLRTVESVSAKDPLTLIVKTTIPNPDLPLNLASVHI
VSKHIGEKSNTEDYNAGRAVVGTGPFKFVAYTPGERVVMARNDAYWGGKSPWEKVNYRYINNAAARTANLLSGEVDVIDK
VSVADLARLRQSPGVKVYAYPGLRVMLLQPSFRQGPNEYLTGNDGKPLPNNPLLDVRVRRALSLAIDRRAIVDRILQGAA
TVANQWMPADTFGYNPEVKDIAYDPAQARKLLAEAGFAQGFNLVMHVPNDRYPQGPETAQAVAQFWTRIGVKAKVEVVPW
SVYASRANKNDYAMSMLAWGNGTGEASYALVNVLATVDAKKGLGASNWGHYSNQAVDHALDASTEEFNTEKRAAILRHSV
KVVSDDVGVLPLYHYQNVWAAKKGLKVTPMTSDRTAAMMVTQDGK
>Mature_525_residues
MKRLLASSLAVALLAAAALPGPAGAQTLSIGFADPLSSLDPQLNNHAGDRSVDVHFWDLLVENKWNRLQPGLALAWKPLD
PKTWEFKLRPGVKWQDGKPFTADDVIFSYQRARSVPGSVATFAGYLRTVESVSAKDPLTLIVKTTIPNPDLPLNLASVHI
VSKHIGEKSNTEDYNAGRAVVGTGPFKFVAYTPGERVVMARNDAYWGGKSPWEKVNYRYINNAAARTANLLSGEVDVIDK
VSVADLARLRQSPGVKVYAYPGLRVMLLQPSFRQGPNEYLTGNDGKPLPNNPLLDVRVRRALSLAIDRRAIVDRILQGAA
TVANQWMPADTFGYNPEVKDIAYDPAQARKLLAEAGFAQGFNLVMHVPNDRYPQGPETAQAVAQFWTRIGVKAKVEVVPW
SVYASRANKNDYAMSMLAWGNGTGEASYALVNVLATVDAKKGLGASNWGHYSNQAVDHALDASTEEFNTEKRAAILRHSV
KVVSDDVGVLPLYHYQNVWAAKKGLKVTPMTSDRTAAMMVTQDGK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=530, Percent_Identity=28.4905660377358, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081878, Length=550, Percent_Identity=25.8181818181818, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=27.2211720226843, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787495, Length=537, Percent_Identity=24.9534450651769, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787551, Length=548, Percent_Identity=25.9124087591241, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787762, Length=518, Percent_Identity=26.6409266409266, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787052, Length=518, Percent_Identity=25.4826254826255, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789887, Length=302, Percent_Identity=23.1788079470199, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57346; Mature: 57346

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLASSLAVALLAAAALPGPAGAQTLSIGFADPLSSLDPQLNNHAGDRSVDVHFWDLL
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEEEH
VENKWNRLQPGLALAWKPLDPKTWEFKLRPGVKWQDGKPFTADDVIFSYQRARSVPGSVA
HHCCCCCCCCCCEEEEECCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCHHH
TFAGYLRTVESVSAKDPLTLIVKTTIPNPDLPLNLASVHIVSKHIGEKSNTEDYNAGRAV
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEE
VGTGPFKFVAYTPGERVVMARNDAYWGGKSPWEKVNYRYINNAAARTANLLSGEVDVIDK
EECCCEEEEEECCCCEEEEEECCCCCCCCCCHHHCCEEEECCHHHHHHHHHCCCCCHHHC
VSVADLARLRQSPGVKVYAYPGLRVMLLQPSFRQGPNEYLTGNDGKPLPNNPLLDVRVRR
CCHHHHHHHHCCCCCEEEEECCEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
ALSLAIDRRAIVDRILQGAATVANQWMPADTFGYNPEVKDIAYDPAQARKLLAEAGFAQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECCHHHHHHHHHHHCCCCC
FNLVMHVPNDRYPQGPETAQAVAQFWTRIGVKAKVEVVPWSVYASRANKNDYAMSMLAWG
CEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEHHHHCCCCCCCEEEEEEEC
NGTGEASYALVNVLATVDAKKGLGASNWGHYSNQAVDHALDASTEEFNTEKRAAILRHSV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHCHHHHHHHHHHHH
KVVSDDVGVLPLYHYQNVWAAKKGLKVTPMTSDRTAAMMVTQDGK
HHCCCCCCEEEEHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKRLLASSLAVALLAAAALPGPAGAQTLSIGFADPLSSLDPQLNNHAGDRSVDVHFWDLL
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEEEH
VENKWNRLQPGLALAWKPLDPKTWEFKLRPGVKWQDGKPFTADDVIFSYQRARSVPGSVA
HHCCCCCCCCCCEEEEECCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCHHH
TFAGYLRTVESVSAKDPLTLIVKTTIPNPDLPLNLASVHIVSKHIGEKSNTEDYNAGRAV
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEE
VGTGPFKFVAYTPGERVVMARNDAYWGGKSPWEKVNYRYINNAAARTANLLSGEVDVIDK
EECCCEEEEEECCCCEEEEEECCCCCCCCCCHHHCCEEEECCHHHHHHHHHCCCCCHHHC
VSVADLARLRQSPGVKVYAYPGLRVMLLQPSFRQGPNEYLTGNDGKPLPNNPLLDVRVRR
CCHHHHHHHHCCCCCEEEEECCEEEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
ALSLAIDRRAIVDRILQGAATVANQWMPADTFGYNPEVKDIAYDPAQARKLLAEAGFAQG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECCHHHHHHHHHHHCCCCC
FNLVMHVPNDRYPQGPETAQAVAQFWTRIGVKAKVEVVPWSVYASRANKNDYAMSMLAWG
CEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEHHHHCCCCCCCEEEEEEEC
NGTGEASYALVNVLATVDAKKGLGASNWGHYSNQAVDHALDASTEEFNTEKRAAILRHSV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHCHHHHHHHHHHHH
KVVSDDVGVLPLYHYQNVWAAKKGLKVTPMTSDRTAAMMVTQDGK
HHCCCCCCEEEEHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]