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The map label for this gene is cysI2 [H]

Identifier: 17546581

GI number: 17546581

Start: 2045649

End: 2047382

Strand: Direct

Name: cysI2 [H]

Synonym: RSc1862

Alternate gene names: 17546581

Gene position: 2045649-2047382 (Clockwise)

Preceding gene: 17546580

Following gene: 17546582

Centisome position: 55.04

GC content: 67.3

Gene sequence:

>1734_bases
ATGTACATCTACGACGCCATTGACCAGCAGCTTGTCGACGAACGCGTCGTCCAGTTCTCGGACCAGACGCGCCGTTTCCT
GAGCGGGCAGCTCACCGAGGATGAGTTTCGCGTGCTGCGGCTGCAGAACGGCCTGTATCTCCAGCGCCATGCGCCGATGC
TGCGCGTGGCGATTCCATACGGCATGCTCGCGTCCCGGCAACTGCGCAAGCTGGCCGGGATCGCCAGGCGCTGGGACCGC
GGCTACGGCCACTTCAGCACCCGGCAGAACCTGCAGTTCAACTGGCCGCGGCTCGAAGACGCCCCCGCCATCCTGGCCGA
ACTGGCCACGGTCCAGATGCACGCCATCCAGACCAGCGGCAACTGCATCCGCAACACCACGACGGACCACTTTGCCGGCA
TTGCACCCGACGAGATCGTCAACCCGCTCGTCTGGTGCGAAATCATTCGGCAATGGTCGATGCTCCATCCCGAATTCGCG
TTCCTGCCGCGCAAGTTCAAGATCGCGGTCAGCGGCGCGTTGACCGACCGGGCAGCGGTCGGCATACACGACATCGGGCT
GCAGGCGGTCGGGCAGGACGGACGGATCGGCTTCCGGGTGTGGGTGGGCGGCGGCATGGGCCGGACCCCGATGGTGGGCA
AGCTGATCCATCCCTTCGTGCCCTGGCAGGATCTGCTGACCTACCTGCAGGCCACGCTGCGCGTCTATAACCTGCACGGG
CGCCGCGACAACAAGTACAAGGCGCGCATCAAGATCCTGGTGAAAGACCTGACGCCCGAGGTGTTCCGCCGGCAGGTGGA
CGAGCAGTGGCGGCCGATCCGCGGGGGGCCGGACACGGTCACCGAGGCATTTGTCGACTCGGTCGCGGCGCGCTTCACCG
TCTCCCCTTATGACGCCCAAGCGGCGAACGATCCCGATGACACGGCGGCGCTGGCCGAGGCGAACCCGTCGTTCCGGCGC
TGGCTCCGCGGCAACGTGCACCCGCATCGCGTACCGGGCTACGTCGCGGTGACCGCGTCATTGAAAGCGCCGGGCCGGGC
GCCGGGCGACATCACGGCCGAACAGATGGAGACCATGGCAGACCTGGCCGACCGTTACGGCTTCGGCGAGCTGCGCGTCT
CCCACGAGCAGAACCTGATCCTTGCCGATGTCCGGCGCAGCGGCCTCTTTGCGCTGTGGCAGGACCTCGGCGCCGCCGGA
CTCGCGACGCCCAACATCGGCAAGATCACGAACATCATCGCCTGCCCCGGCGGAGACTTCTGCGCACTCGCCAATGCGGT
GTCGATCCCCCTTGCCCAGGCCATCCACGCGCGCTTCGATGACCTGGACCACGTGCACGACATCGGCGAACTGGACCTGA
ACATCTCCGGGTGCATCAACGCCTGCGGGCACCACCACATCGGCCATATCGGGATCCTCGGCGTCGACAAGGCCGGAGAA
GCCTGGTACCAGATCACCCTGGGCGGCCGGCAGAATGGGGCCGGCGGGCCGGAAGGGAGCGATTCGCCCGCGGCCATCGG
CCGGATCATCGGCCCGTCCTTTGCCCAGGCCCAGGTGCCGGACGTGATCGAACGGCTGATCGACACCTATCTCGCGCACC
GCGACAGCGATGCCGAACGATTCGTCGACGTGGTCGGCCGGATCGGCATCGAGCCCTTTCAGGCCGCGGTGTACCCGGAC
GCGGCCATCGCGGCGCGGCGCTCACACGCAGAGGTAGCGCATGGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GGGTCATGCACAACGCCAACGAGAACATGATGCCGACCGACATGTCGGTCGAGCGGGCACGCGCGCGCGACTAGCCCGCA
GCGCAAGGAGACATCCCACG

Downstream 100 bases:

>100_bases
CGCAACCGCTCGCGATGCACCGTGCAACATCCTCTGCGACGGCCGCGTGACGGCGGACACCTGGCGGGCCTATCCCGTGG
AGCACGGTAATGGGGACCAG

Product: sulfite reductase oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MYIYDAIDQQLVDERVVQFSDQTRRFLSGQLTEDEFRVLRLQNGLYLQRHAPMLRVAIPYGMLASRQLRKLAGIARRWDR
GYGHFSTRQNLQFNWPRLEDAPAILAELATVQMHAIQTSGNCIRNTTTDHFAGIAPDEIVNPLVWCEIIRQWSMLHPEFA
FLPRKFKIAVSGALTDRAAVGIHDIGLQAVGQDGRIGFRVWVGGGMGRTPMVGKLIHPFVPWQDLLTYLQATLRVYNLHG
RRDNKYKARIKILVKDLTPEVFRRQVDEQWRPIRGGPDTVTEAFVDSVAARFTVSPYDAQAANDPDDTAALAEANPSFRR
WLRGNVHPHRVPGYVAVTASLKAPGRAPGDITAEQMETMADLADRYGFGELRVSHEQNLILADVRRSGLFALWQDLGAAG
LATPNIGKITNIIACPGGDFCALANAVSIPLAQAIHARFDDLDHVHDIGELDLNISGCINACGHHHIGHIGILGVDKAGE
AWYQITLGGRQNGAGGPEGSDSPAAIGRIIGPSFAQAQVPDVIERLIDTYLAHRDSDAERFVDVVGRIGIEPFQAAVYPD
AAIAARRSHAEVAHGGA

Sequences:

>Translated_577_residues
MYIYDAIDQQLVDERVVQFSDQTRRFLSGQLTEDEFRVLRLQNGLYLQRHAPMLRVAIPYGMLASRQLRKLAGIARRWDR
GYGHFSTRQNLQFNWPRLEDAPAILAELATVQMHAIQTSGNCIRNTTTDHFAGIAPDEIVNPLVWCEIIRQWSMLHPEFA
FLPRKFKIAVSGALTDRAAVGIHDIGLQAVGQDGRIGFRVWVGGGMGRTPMVGKLIHPFVPWQDLLTYLQATLRVYNLHG
RRDNKYKARIKILVKDLTPEVFRRQVDEQWRPIRGGPDTVTEAFVDSVAARFTVSPYDAQAANDPDDTAALAEANPSFRR
WLRGNVHPHRVPGYVAVTASLKAPGRAPGDITAEQMETMADLADRYGFGELRVSHEQNLILADVRRSGLFALWQDLGAAG
LATPNIGKITNIIACPGGDFCALANAVSIPLAQAIHARFDDLDHVHDIGELDLNISGCINACGHHHIGHIGILGVDKAGE
AWYQITLGGRQNGAGGPEGSDSPAAIGRIIGPSFAQAQVPDVIERLIDTYLAHRDSDAERFVDVVGRIGIEPFQAAVYPD
AAIAARRSHAEVAHGGA
>Mature_577_residues
MYIYDAIDQQLVDERVVQFSDQTRRFLSGQLTEDEFRVLRLQNGLYLQRHAPMLRVAIPYGMLASRQLRKLAGIARRWDR
GYGHFSTRQNLQFNWPRLEDAPAILAELATVQMHAIQTSGNCIRNTTTDHFAGIAPDEIVNPLVWCEIIRQWSMLHPEFA
FLPRKFKIAVSGALTDRAAVGIHDIGLQAVGQDGRIGFRVWVGGGMGRTPMVGKLIHPFVPWQDLLTYLQATLRVYNLHG
RRDNKYKARIKILVKDLTPEVFRRQVDEQWRPIRGGPDTVTEAFVDSVAARFTVSPYDAQAANDPDDTAALAEANPSFRR
WLRGNVHPHRVPGYVAVTASLKAPGRAPGDITAEQMETMADLADRYGFGELRVSHEQNLILADVRRSGLFALWQDLGAAG
LATPNIGKITNIIACPGGDFCALANAVSIPLAQAIHARFDDLDHVHDIGELDLNISGCINACGHHHIGHIGILGVDKAGE
AWYQITLGGRQNGAGGPEGSDSPAAIGRIIGPSFAQAQVPDVIERLIDTYLAHRDSDAERFVDVVGRIGIEPFQAAVYPD
AAIAARRSHAEVAHGGA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 63508; Mature: 63508

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIYDAIDQQLVDERVVQFSDQTRRFLSGQLTEDEFRVLRLQNGLYLQRHAPMLRVAIPY
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCEEEECCCCEEEEECCH
GMLASRQLRKLAGIARRWDRGYGHFSTRQNLQFNWPRLEDAPAILAELATVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHEEEECCC
NCIRNTTTDHFAGIAPDEIVNPLVWCEIIRQWSMLHPEFAFLPRKFKIAVSGALTDRAAV
CEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCHHHC
GIHDIGLQAVGQDGRIGFRVWVGGGMGRTPMVGKLIHPFVPWQDLLTYLQATLRVYNLHG
CCHHCCHHEECCCCCEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
RRDNKYKARIKILVKDLTPEVFRRQVDEQWRPIRGGPDTVTEAFVDSVAARFTVSPYDAQ
CCCCCCEEEEEEHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCC
AANDPDDTAALAEANPSFRRWLRGNVHPHRVPGYVAVTASLKAPGRAPGDITAEQMETMA
CCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
DLADRYGFGELRVSHEQNLILADVRRSGLFALWQDLGAAGLATPNIGKITNIIACPGGDF
HHHHHCCCCCEEECCCCCEEEEHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCH
CALANAVSIPLAQAIHARFDDLDHVHDIGELDLNISGCINACGHHHIGHIGILGVDKAGE
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCC
AWYQITLGGRQNGAGGPEGSDSPAAIGRIIGPSFAQAQVPDVIERLIDTYLAHRDSDAER
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHCCCCCHHH
FVDVVGRIGIEPFQAAVYPDAAIAARRSHAEVAHGGA
HHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYIYDAIDQQLVDERVVQFSDQTRRFLSGQLTEDEFRVLRLQNGLYLQRHAPMLRVAIPY
CEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCEEEECCCCEEEEECCH
GMLASRQLRKLAGIARRWDRGYGHFSTRQNLQFNWPRLEDAPAILAELATVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHEEEECCC
NCIRNTTTDHFAGIAPDEIVNPLVWCEIIRQWSMLHPEFAFLPRKFKIAVSGALTDRAAV
CEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCHHHC
GIHDIGLQAVGQDGRIGFRVWVGGGMGRTPMVGKLIHPFVPWQDLLTYLQATLRVYNLHG
CCHHCCHHEECCCCCEEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
RRDNKYKARIKILVKDLTPEVFRRQVDEQWRPIRGGPDTVTEAFVDSVAARFTVSPYDAQ
CCCCCCEEEEEEHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCC
AANDPDDTAALAEANPSFRRWLRGNVHPHRVPGYVAVTASLKAPGRAPGDITAEQMETMA
CCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
DLADRYGFGELRVSHEQNLILADVRRSGLFALWQDLGAAGLATPNIGKITNIIACPGGDF
HHHHHCCCCCEEECCCCCEEEEHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCH
CALANAVSIPLAQAIHARFDDLDHVHDIGELDLNISGCINACGHHHIGHIGILGVDKAGE
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCC
AWYQITLGGRQNGAGGPEGSDSPAAIGRIIGPSFAQAQVPDVIERLIDTYLAHRDSDAER
EEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHCCCCCHHH
FVDVVGRIGIEPFQAAVYPDAAIAARRSHAEVAHGGA
HHHHHHHCCCCHHHHHCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]