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The map label for this gene is surA [C]

Identifier: 17546463

GI number: 17546463

Start: 1866710

End: 1867477

Strand: Reverse

Name: surA [C]

Synonym: RSc1744

Alternate gene names: 17546463

Gene position: 1867477-1866710 (Counterclockwise)

Preceding gene: 17546464

Following gene: 17546462

Centisome position: 50.25

GC content: 64.58

Gene sequence:

>768_bases
ATGGCTGCCGCCCTCCTTGCGACCGCCGCTCCCGCCATGGCGCAGAACGCCGCCATGGTCAACGGGCACGCCATCCCGAG
CGCCAAGGTGGACGCACTGATCAAGAAGTCCGGCCAGCCCGAATCGCCGGAGCTGCGCAACCGCGCCCGCGACATGCTGA
TCGACCGCGAACTGATCGAGCAGGACGCCACCAATCGCGGCCTGCTGGGGCGTGACGACGTGCAGGAGCAACTGGCCCAG
GCGCGCCTGAACGTGCTGGTCGCCGCCGAATTCGAGGACTACGTCAAGAACAGCCCGACCACTGACGACGACCTGCGCAA
GCAATACGAAAAGATCAAGGCCCAGTTCGGCAACGGCAAGGAATACCACGCCCACCACATCCTGGTGGACAAGGAAGCCG
ACGCGAAGGCCATCATCGCCAAGCTCAAGGCCGGCGGCAATTTCGAAGAGATCGCCAAGGCGCAGTCGAAGGACAAGGGA
TCGGGCGCCAACGGTGGCGACCTGGATTGGGCGAACCCGGGCACCTACGTGCCGGAGTTCTCCGCCGCCCTGACCGGCCT
GAAGAAGGGCGAGGTCACCCAGACGCCCGTCAAGACGCAGTTCGGCTGGCACGTGATCCGCCTGGACGATACGCGCGACG
CCAAGATCCCGGCCTTCGAAGACGTCAAGCCGCAGCTGCTCGAGATGATGATGGGCGACCAGAACTGGCAGCGCGCCAAG
TTCCAGGCCATGCTGAAGGATCTGCGCGAAAAGGCGACGATCAAGTAA

Upstream 100 bases:

>100_bases
GCGCCGTGACGCCCGAAGAAAACACGTAAGCGCATCACACGCTCACTCGTCCTTCCTTTCAACGCATCCCATGAAAGTTT
CCAGCCTTACCGCCAGCCTG

Downstream 100 bases:

>100_bases
GCGGATGACCTGCCGAGCGAGGCAGGAACAGAAAGACGCCATGCGCCGGATGCCGTTCAGTCGAGACTGAACGGCATTTT
TCATTGGGGCGGCGAAGCGG

Product: isomerase rotamase signal peptide protein

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAAALLATAAPAMAQNAAMVNGHAIPSAKVDALIKKSGQPESPELRNRARDMLIDRELIEQDATNRGLLGRDDVQEQLAQ
ARLNVLVAAEFEDYVKNSPTTDDDLRKQYEKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGGNFEEIAKAQSKDKG
SGANGGDLDWANPGTYVPEFSAALTGLKKGEVTQTPVKTQFGWHVIRLDDTRDAKIPAFEDVKPQLLEMMMGDQNWQRAK
FQAMLKDLREKATIK

Sequences:

>Translated_255_residues
MAAALLATAAPAMAQNAAMVNGHAIPSAKVDALIKKSGQPESPELRNRARDMLIDRELIEQDATNRGLLGRDDVQEQLAQ
ARLNVLVAAEFEDYVKNSPTTDDDLRKQYEKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGGNFEEIAKAQSKDKG
SGANGGDLDWANPGTYVPEFSAALTGLKKGEVTQTPVKTQFGWHVIRLDDTRDAKIPAFEDVKPQLLEMMMGDQNWQRAK
FQAMLKDLREKATIK
>Mature_254_residues
AAALLATAAPAMAQNAAMVNGHAIPSAKVDALIKKSGQPESPELRNRARDMLIDRELIEQDATNRGLLGRDDVQEQLAQA
RLNVLVAAEFEDYVKNSPTTDDDLRKQYEKIKAQFGNGKEYHAHHILVDKEADAKAIIAKLKAGGNFEEIAKAQSKDKGS
GANGGDLDWANPGTYVPEFSAALTGLKKGEVTQTPVKTQFGWHVIRLDDTRDAKIPAFEDVKPQLLEMMMGDQNWQRAKF
QAMLKDLREKATIK

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=101, Percent_Identity=35.6435643564356, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1786238, Length=122, Percent_Identity=40.9836065573771, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786645, Length=126, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28064; Mature: 27933

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAALLATAAPAMAQNAAMVNGHAIPSAKVDALIKKSGQPESPELRNRARDMLIDRELIE
CCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QDATNRGLLGRDDVQEQLAQARLNVLVAAEFEDYVKNSPTTDDDLRKQYEKIKAQFGNGK
HCCCCCCCCCHHHHHHHHHHHHHHEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
EYHAHHILVDKEADAKAIIAKLKAGGNFEEIAKAQSKDKGSGANGGDLDWANPGTYVPEF
CEEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
SAALTGLKKGEVTQTPVKTQFGWHVIRLDDTRDAKIPAFEDVKPQLLEMMMGDQNWQRAK
HHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHCCCCHHHHH
FQAMLKDLREKATIK
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAALLATAAPAMAQNAAMVNGHAIPSAKVDALIKKSGQPESPELRNRARDMLIDRELIE
CHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QDATNRGLLGRDDVQEQLAQARLNVLVAAEFEDYVKNSPTTDDDLRKQYEKIKAQFGNGK
HCCCCCCCCCHHHHHHHHHHHHHHEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
EYHAHHILVDKEADAKAIIAKLKAGGNFEEIAKAQSKDKGSGANGGDLDWANPGTYVPEF
CEEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
SAALTGLKKGEVTQTPVKTQFGWHVIRLDDTRDAKIPAFEDVKPQLLEMMMGDQNWQRAK
HHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHCCCCHHHHH
FQAMLKDLREKATIK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]