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The map label for this gene is hpcR [H]

Identifier: 17546311

GI number: 17546311

Start: 1707754

End: 1708218

Strand: Reverse

Name: hpcR [H]

Synonym: RSc1592

Alternate gene names: 17546311

Gene position: 1708218-1707754 (Counterclockwise)

Preceding gene: 17546312

Following gene: 17546308

Centisome position: 45.96

GC content: 67.96

Gene sequence:

>465_bases
ATGGTTTCGACCTTCAAGCGCCGCAACCTACCGCACTTGCTGCTGCGTGCCCGCGAGACGCTCATGGCGCGTTTCCGGCC
CATCCTGCGCGAGCACGGCATCACCGAGCAGCAGTGGCGCGTGCTGCGTACCCTCAACGACACCGGCGACATGGAGCCCA
ACCAGCTCGCCGACGCCTGCCTGATCCTGAGCCCGAGCCTGACGCGCATGCTGGCCGCGATGGAGCAGGCCGACATGATC
GTACGCACGCGCTCGTCGGTGGACCAGCGCCGCCAGGTCATCTCGCTGACCCCCAAGAGCCGCCGGTTCCTGGCCGACGT
CGAACCGCAGGTGGACGCGACATACGCAAACATCGAGAGCCAGCTCGGCCGCCCGCGGCTGGAGGCGCTCTACCGCGTCA
TCGACGAGGCCATCCAGTTGATGGAAGCGCCCGCCACGGACAAACGCCTCCCGGCCGACGACTGA

Upstream 100 bases:

>100_bases
GTCGTGCCATATCGACCGCGTGCCGCGCGGCTGGGAACAGCCTTCGGACCATACGCCCGTGGTCGCCGCCCTGCGTGACG
CCTGAGCCCGCGCGATCCGC

Downstream 100 bases:

>100_bases
CCGCCCGCCCGCGATACCGAGACGTCAGTACACCGCGCCGGCCTGCCCCGGCACGGGTGCGCCCGCGCCAGCGCCAGCGC
CAGCGAACGACCGCGCCAAC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVSTFKRRNLPHLLLRARETLMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQADMI
VRTRSSVDQRRQVISLTPKSRRFLADVEPQVDATYANIESQLGRPRLEALYRVIDEAIQLMEAPATDKRLPADD

Sequences:

>Translated_154_residues
MVSTFKRRNLPHLLLRARETLMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQADMI
VRTRSSVDQRRQVISLTPKSRRFLADVEPQVDATYANIESQLGRPRLEALYRVIDEAIQLMEAPATDKRLPADD
>Mature_154_residues
MVSTFKRRNLPHLLLRARETLMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADACLILSPSLTRMLAAMEQADMI
VRTRSSVDQRRQVISLTPKSRRFLADVEPQVDATYANIESQLGRPRLEALYRVIDEAIQLMEAPATDKRLPADD

Specific function: Repressor for the homoprotocatechuate catabolic pathway hpc operon [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012712
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17724; Mature: 17724

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTFKRRNLPHLLLRARETLMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADAC
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LILSPSLTRMLAAMEQADMIVRTRSSVDQRRQVISLTPKSRRFLADVEPQVDATYANIES
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
QLGRPRLEALYRVIDEAIQLMEAPATDKRLPADD
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVSTFKRRNLPHLLLRARETLMARFRPILREHGITEQQWRVLRTLNDTGDMEPNQLADAC
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
LILSPSLTRMLAAMEQADMIVRTRSSVDQRRQVISLTPKSRRFLADVEPQVDATYANIES
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH
QLGRPRLEALYRVIDEAIQLMEAPATDKRLPADD
HHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384293; 8550403 [H]