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The map label for this gene is yciR [C]

Identifier: 17546264

GI number: 17546264

Start: 1651021

End: 1653351

Strand: Reverse

Name: yciR [C]

Synonym: RSc1545

Alternate gene names: 17546264

Gene position: 1653351-1651021 (Counterclockwise)

Preceding gene: 17546268

Following gene: 17546262

Centisome position: 44.49

GC content: 68.9

Gene sequence:

>2331_bases
ATGACGATGAAAGCGCTTGCGGGCCGGGTAGCCCGCTTCATGGGCGTGCCGGCCGACAACCCGGAGCTGCTCAAGGCGCA
GTACCGCGCCTTCTCGCGCCAGTTGCCGATGATGTACTTCATCCTCATCTCGAGCACCTGGGCGGTCGCCCTCACCTACC
GCGCCATCACCCCGGCCTGGCTGACGGTCGGGATACCGCTGCTGCTGACGCTGGCCTGCGCGATACGCGTGCTGCACTGG
TGGCAGTCCCGCCGCATCGACCCGACACCCGAGCTCGCCCTGGGCGCCCTCACGCGCACCAACCGGCTGGCCAGCGTCAT
CGCCGTGTCGTTCACAGCCTGGTCGCTCGCGCTGTTCCACTATGGCGACGCCTATACGCGGTCGTACCTGGCCTTCTACA
TGGCCATCACCGTGATCGCCTGCATCTTCTGCCTGATGCATCTGCGCTCGGCCGCCATCACGGTCACGGCGATCGTCAAC
GGGGCGTTCATCGCCTTCTTCGCGGCGACGGGCCAGCCGACCTTCATTGCGATCGCCATCAACATGGCCCTGGTGTCGTT
CGGCCTGCTGGTCATCCTGATGGTCAACTACCGCGACTTCACCCTCATGGTGAACGCGCAGACCGAAGCCCGACGCCGCG
AAGCGGAGCAAAGCCGCCTGCTGCACATGATCGACGACATGCCGGTCGCCGTCATGACGGTGGAGCCGGGCACGTTCGCC
ATCAACTACGCCAACAACACGTCCAAGCGGCTGATCGACCGGATCGCGCACCTGCTGCCGATCGAGCCCGACGCCCTGCT
CGGCACCTCCATCGACGTCTTCCACGCGCATCCGGAACACCAGCGCCGGCTGCTCGCCGATCCGGCCAACCTGCCGCACA
ACACGCGCATCCGGCTCGGGCCCGAGGTGCTGGACCTGAAGGTCTCGGCGGTCCGGGCCAACGACGGCAGCTACATCGGG
CCCATGCTGACCTGGGCGCTGGTGACCAAGGAGGTGGAGGCCGAGAACCGCATCCGCCAGCTCGCCCACTACGACACGCT
CACCGGCCTGGCCAACCGCACCAACTTCCGCGAACAGCTCGATGCCCGCCTCGCGGCGCCCGAGGCCCGCCTCGGCTTGC
TGTATATCGACCTCGACGGCTTCAAGCTCGTCAACGACACCAAGGGGCACCGGGCCGGAGACGCGCTGCTCGAACGGGTC
GCGCAGCGGCTGCGCGCGGTCTGTGACCGCCCCGGCATGGCCATCGCGCGGCTGGGCGGCGACGAATTCGCCGTGCTCGT
GCCGCACGACGATGCCGATCGCGCGGCGACGCTGGCCACCGCGCTGATCGAAGCACTCGGTGCGCCGTATGCCCTCGGTG
CCGACCAGAACGTCCGGATCGGAGCATCGATCGGCATCGCGCTCGCCCCCGCCCACGGCCGCGATACCGAGAACCTGCTC
GCCCGCGCCGACATCGCGCTCTACGCCGCCAAGGCCGCCGGCAAGGGCCTGGCACGCCTGTTCTGCGCGGACATGGAAAC
GCGCATCCAGGCGCGCGCGCTGCTGGAAGCGCAGCTGCGCGCCGCCCTCGAGCACCAGGACCGCCTGTTCGTCTTCTACC
AGCCGATCGTCGATGTCGCGACCGGCAAGGTCACCGCGCGCGAAGCGCTGGTGCGCTGGCACCATGCGGAACGGGGCTGG
GTCCCGCCCGACGAGTTCGTCCCCATTGCCGAACAGAGCGGCCTCATCGACCAGCTCGGCCGCTTCGTGCTGCATCGCGC
CTGCCGCGAAGCGACCCGCTGGGAAGACGGCGCGCGCGTGGCCGTCAATGTGTCGCCCATGCAGCTGGGCAAGGCGACAC
TGGCGCAGACGGTGCACGCGGCGCTGATCGACTCCGGCCTGGCGCCCGACCGCCTCGAGATCGAGGTCACGGAGACCGCC
CTCATCCAGAACGAAGCGGAAAGCTTCGAAGACCTGCGCCAGCTCTATGACATGGGCGTGCGCGTCGCCCTCGACGACTT
CGGCACCGGCTATTCATCGCTGGCCCATCTGCGGGCCTTCCCGTTCGACAAGATCAAGATCGACCGCTCGTTCGTCCGCG
ACCTTCTCGAGCGGCCGGACAGCGCGGTCCTGGTCAGAGCCATCGCCGACCTCGGCCGGCAGCTCGGCGTGACCACCGTG
GCCGAAGGCGTGGAAACGCAAGCGCACGTGAGAGGCATCCGGGAAGCCGGATGCACCGAGGCCCAGGGGTACTACTACGG
CCGGCCGGCGCCGAGCGACGAAGACCGGCCGCGCGTGGAGGCCTGCGGCCCAGCGCGGACGGATGCCGCGTTGGCTTCCT
GCGCCGGCTGA

Upstream 100 bases:

>100_bases
GCGCATTGCCGTCGCCGCGTGCGTCGGGCGCCCCTTCCAGCCCGGCGTCGAATCCGCGCGCCGAGGCCCGATCGGGCCGC
TCCGACAACAGGAGCGCCCA

Downstream 100 bases:

>100_bases
CACGATCACAGCGCGTTCAGCGGAATCTTCAGATACCGCACGCCATTCGGCTCGGCCGGCGGCAGCGCGCCCGCCCGGAT
GTTGACCTGGATGGACGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MTMKALAGRVARFMGVPADNPELLKAQYRAFSRQLPMMYFILISSTWAVALTYRAITPAWLTVGIPLLLTLACAIRVLHW
WQSRRIDPTPELALGALTRTNRLASVIAVSFTAWSLALFHYGDAYTRSYLAFYMAITVIACIFCLMHLRSAAITVTAIVN
GAFIAFFAATGQPTFIAIAINMALVSFGLLVILMVNYRDFTLMVNAQTEARRREAEQSRLLHMIDDMPVAVMTVEPGTFA
INYANNTSKRLIDRIAHLLPIEPDALLGTSIDVFHAHPEHQRRLLADPANLPHNTRIRLGPEVLDLKVSAVRANDGSYIG
PMLTWALVTKEVEAENRIRQLAHYDTLTGLANRTNFREQLDARLAAPEARLGLLYIDLDGFKLVNDTKGHRAGDALLERV
AQRLRAVCDRPGMAIARLGGDEFAVLVPHDDADRAATLATALIEALGAPYALGADQNVRIGASIGIALAPAHGRDTENLL
ARADIALYAAKAAGKGLARLFCADMETRIQARALLEAQLRAALEHQDRLFVFYQPIVDVATGKVTAREALVRWHHAERGW
VPPDEFVPIAEQSGLIDQLGRFVLHRACREATRWEDGARVAVNVSPMQLGKATLAQTVHAALIDSGLAPDRLEIEVTETA
LIQNEAESFEDLRQLYDMGVRVALDDFGTGYSSLAHLRAFPFDKIKIDRSFVRDLLERPDSAVLVRAIADLGRQLGVTTV
AEGVETQAHVRGIREAGCTEAQGYYYGRPAPSDEDRPRVEACGPARTDAALASCAG

Sequences:

>Translated_776_residues
MTMKALAGRVARFMGVPADNPELLKAQYRAFSRQLPMMYFILISSTWAVALTYRAITPAWLTVGIPLLLTLACAIRVLHW
WQSRRIDPTPELALGALTRTNRLASVIAVSFTAWSLALFHYGDAYTRSYLAFYMAITVIACIFCLMHLRSAAITVTAIVN
GAFIAFFAATGQPTFIAIAINMALVSFGLLVILMVNYRDFTLMVNAQTEARRREAEQSRLLHMIDDMPVAVMTVEPGTFA
INYANNTSKRLIDRIAHLLPIEPDALLGTSIDVFHAHPEHQRRLLADPANLPHNTRIRLGPEVLDLKVSAVRANDGSYIG
PMLTWALVTKEVEAENRIRQLAHYDTLTGLANRTNFREQLDARLAAPEARLGLLYIDLDGFKLVNDTKGHRAGDALLERV
AQRLRAVCDRPGMAIARLGGDEFAVLVPHDDADRAATLATALIEALGAPYALGADQNVRIGASIGIALAPAHGRDTENLL
ARADIALYAAKAAGKGLARLFCADMETRIQARALLEAQLRAALEHQDRLFVFYQPIVDVATGKVTAREALVRWHHAERGW
VPPDEFVPIAEQSGLIDQLGRFVLHRACREATRWEDGARVAVNVSPMQLGKATLAQTVHAALIDSGLAPDRLEIEVTETA
LIQNEAESFEDLRQLYDMGVRVALDDFGTGYSSLAHLRAFPFDKIKIDRSFVRDLLERPDSAVLVRAIADLGRQLGVTTV
AEGVETQAHVRGIREAGCTEAQGYYYGRPAPSDEDRPRVEACGPARTDAALASCAG
>Mature_775_residues
TMKALAGRVARFMGVPADNPELLKAQYRAFSRQLPMMYFILISSTWAVALTYRAITPAWLTVGIPLLLTLACAIRVLHWW
QSRRIDPTPELALGALTRTNRLASVIAVSFTAWSLALFHYGDAYTRSYLAFYMAITVIACIFCLMHLRSAAITVTAIVNG
AFIAFFAATGQPTFIAIAINMALVSFGLLVILMVNYRDFTLMVNAQTEARRREAEQSRLLHMIDDMPVAVMTVEPGTFAI
NYANNTSKRLIDRIAHLLPIEPDALLGTSIDVFHAHPEHQRRLLADPANLPHNTRIRLGPEVLDLKVSAVRANDGSYIGP
MLTWALVTKEVEAENRIRQLAHYDTLTGLANRTNFREQLDARLAAPEARLGLLYIDLDGFKLVNDTKGHRAGDALLERVA
QRLRAVCDRPGMAIARLGGDEFAVLVPHDDADRAATLATALIEALGAPYALGADQNVRIGASIGIALAPAHGRDTENLLA
RADIALYAAKAAGKGLARLFCADMETRIQARALLEAQLRAALEHQDRLFVFYQPIVDVATGKVTAREALVRWHHAERGWV
PPDEFVPIAEQSGLIDQLGRFVLHRACREATRWEDGARVAVNVSPMQLGKATLAQTVHAALIDSGLAPDRLEIEVTETAL
IQNEAESFEDLRQLYDMGVRVALDDFGTGYSSLAHLRAFPFDKIKIDRSFVRDLLERPDSAVLVRAIADLGRQLGVTTVA
EGVETQAHVRGIREAGCTEAQGYYYGRPAPSDEDRPRVEACGPARTDAALASCAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=429, Percent_Identity=38.4615384615385, Blast_Score=293, Evalue=3e-80,
Organism=Escherichia coli, GI87081921, Length=437, Percent_Identity=32.7231121281465, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1787055, Length=498, Percent_Identity=27.3092369477912, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI226510982, Length=413, Percent_Identity=29.5399515738499, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788502, Length=233, Percent_Identity=32.618025751073, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1788381, Length=427, Percent_Identity=30.4449648711944, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI1790496, Length=239, Percent_Identity=32.6359832635983, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=33.75, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI87081743, Length=261, Percent_Identity=30.6513409961686, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786507, Length=225, Percent_Identity=35.1111111111111, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081980, Length=229, Percent_Identity=32.3144104803493, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788849, Length=451, Percent_Identity=25.7206208425721, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87082096, Length=247, Percent_Identity=32.3886639676113, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1789650, Length=429, Percent_Identity=24.4755244755245, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=34.3195266272189, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788956, Length=180, Percent_Identity=35, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=33.7209302325581, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=31.9277108433735, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87082007, Length=197, Percent_Identity=31.9796954314721, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=34.3023255813954, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=36.2068965517241, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787802, Length=158, Percent_Identity=27.8481012658228, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=33.125, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 85187; Mature: 85056

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00136 SUBTILASE_ASP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKALAGRVARFMGVPADNPELLKAQYRAFSRQLPMMYFILISSTWAVALTYRAITPAW
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHEEEEHHCCHHH
LTVGIPLLLTLACAIRVLHWWQSRRIDPTPELALGALTRTNRLASVIAVSFTAWSLALFH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGDAYTRSYLAFYMAITVIACIFCLMHLRSAAITVTAIVNGAFIAFFAATGQPTFIAIAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCEEEEEEECCCCEEEEEHH
NMALVSFGLLVILMVNYRDFTLMVNAQTEARRREAEQSRLLHMIDDMPVAVMTVEPGTFA
HHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEE
INYANNTSKRLIDRIAHLLPIEPDALLGTSIDVFHAHPEHQRRLLADPANLPHNTRIRLG
EEECCCCHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEC
PEVLDLKVSAVRANDGSYIGPMLTWALVTKEVEAENRIRQLAHYDTLTGLANRTNFREQL
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DARLAAPEARLGLLYIDLDGFKLVNDTKGHRAGDALLERVAQRLRAVCDRPGMAIARLGG
HHHHCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEFAVLVPHDDADRAATLATALIEALGAPYALGADQNVRIGASIGIALAPAHGRDTENLL
CCEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECEEEECCCCCCHHHHH
ARADIALYAAKAAGKGLARLFCADMETRIQARALLEAQLRAALEHQDRLFVFYQPIVDVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
TGKVTAREALVRWHHAERGWVPPDEFVPIAEQSGLIDQLGRFVLHRACREATRWEDGARV
CCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
AVNVSPMQLGKATLAQTVHAALIDSGLAPDRLEIEVTETALIQNEAESFEDLRQLYDMGV
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
RVALDDFGTGYSSLAHLRAFPFDKIKIDRSFVRDLLERPDSAVLVRAIADLGRQLGVTTV
EEEECCCCCCHHHHHHHHCCCCHHEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
AEGVETQAHVRGIREAGCTEAQGYYYGRPAPSDEDRPRVEACGPARTDAALASCAG
HHCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TMKALAGRVARFMGVPADNPELLKAQYRAFSRQLPMMYFILISSTWAVALTYRAITPAW
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHEEEEHHCCHHH
LTVGIPLLLTLACAIRVLHWWQSRRIDPTPELALGALTRTNRLASVIAVSFTAWSLALFH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGDAYTRSYLAFYMAITVIACIFCLMHLRSAAITVTAIVNGAFIAFFAATGQPTFIAIAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCEEEEEEECCCCEEEEEHH
NMALVSFGLLVILMVNYRDFTLMVNAQTEARRREAEQSRLLHMIDDMPVAVMTVEPGTFA
HHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEE
INYANNTSKRLIDRIAHLLPIEPDALLGTSIDVFHAHPEHQRRLLADPANLPHNTRIRLG
EEECCCCHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEC
PEVLDLKVSAVRANDGSYIGPMLTWALVTKEVEAENRIRQLAHYDTLTGLANRTNFREQL
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
DARLAAPEARLGLLYIDLDGFKLVNDTKGHRAGDALLERVAQRLRAVCDRPGMAIARLGG
HHHHCCCCCCEEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEFAVLVPHDDADRAATLATALIEALGAPYALGADQNVRIGASIGIALAPAHGRDTENLL
CCEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECEEEECCCCCCHHHHH
ARADIALYAAKAAGKGLARLFCADMETRIQARALLEAQLRAALEHQDRLFVFYQPIVDVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
TGKVTAREALVRWHHAERGWVPPDEFVPIAEQSGLIDQLGRFVLHRACREATRWEDGARV
CCCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
AVNVSPMQLGKATLAQTVHAALIDSGLAPDRLEIEVTETALIQNEAESFEDLRQLYDMGV
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
RVALDDFGTGYSSLAHLRAFPFDKIKIDRSFVRDLLERPDSAVLVRAIADLGRQLGVTTV
EEEECCCCCCHHHHHHHHCCCCHHEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
AEGVETQAHVRGIREAGCTEAQGYYYGRPAPSDEDRPRVEACGPARTDAALASCAG
HHCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]