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The map label for this gene is blh [H]

Identifier: 17546263

GI number: 17546263

Start: 1650155

End: 1651015

Strand: Direct

Name: blh [H]

Synonym: RSc1544

Alternate gene names: 17546263

Gene position: 1650155-1651015 (Clockwise)

Preceding gene: 17546256

Following gene: 17546265

Centisome position: 44.4

GC content: 68.87

Gene sequence:

>861_bases
ATGCCCGCCCAGATTTCGACGTTCTTCGATTCCGATACCTGCACCATGACCTACGTGGTCCATGGCGGGCCGGGCACGCC
GTGCGCGGTGATCGATTCGGTGCTCGACTACGATCCCAAATCCGGCCGCACCCGGACCGGCTCGGCGGACCGGGTGGCGG
CCTACATCGAGGCGAACGCGCTGCGGGTCGAGTGGCTGCTCGAGACGCATGCCCACGCGGACCACCTGTCGGCCGCGCCG
TACCTGCGCAACCGGTTCGGTGGGCGCATTGCCATCGGCGAGCGCATCCGGGTGGTGCAGGGCGTGTTCAAGCCGATCTT
CAACCTGGAGCCGTCGTTCCGGCTCGACGGCTCGCAGTTCGACCACCTGTTCGCCGCGGACGAGGTGTTCCGCATCGGCG
CGCTGGAAGCGAAGGCGCTGTCGGTGCCCGGTCACACGCCGGCCGACATGGCCTACCAGGTGGGCGACGCCGTGTTCGTG
GGCGATACGCTGTTCATGCCGGATGTCGGCACCGCCCGCTGCGATTTTCCCGGCGGCGACGCGCGCACGCTGTACCAGTC
GATCCGCCGCCTGCTGGACTTGCCGCCGCAGACGCGGCTCTACATGTGCCATGACTATCCGCCCGCCGGCCGCGAGGCGA
CCTGCGAGACCACGGTGGCCGAGCAGCGCCGCGCCAATATCCATGTGCGCGACGGCGTGACGGAAGACGACTTCGTGCAG
ATGCGCACCCGGCGCGACGCCACGCTGGCCATGCCGACGCTGATGCTGCCGTCCATCCAGGTCAACATCCGGGCGGGCGC
GCTGCCGCCGGCCGAGCCGAATGGCGTGCGGTATCTGAAGATTCCGCTGAACGCGCTGTGA

Upstream 100 bases:

>100_bases
TCGGGGCATGGCGGGCGCGGTTGTTGAAAGGTGCTCTATTGGCAGACAGAATGTCTGACGATATTCTATTAAAATATAGA
TTGTTTGGGGAAGTCCTGCC

Downstream 100 bases:

>100_bases
TCGTGTCAGCCGGCGCAGGAAGCCAACGCGGCATCCGTCCGCGCTGGGCCGCAGGCCTCCACGCGCGGCCGGTCTTCGTC
GCTCGGCGCCGGCCGGCCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPAQISTFFDSDTCTMTYVVHGGPGTPCAVIDSVLDYDPKSGRTRTGSADRVAAYIEANALRVEWLLETHAHADHLSAAP
YLRNRFGGRIAIGERIRVVQGVFKPIFNLEPSFRLDGSQFDHLFAADEVFRIGALEAKALSVPGHTPADMAYQVGDAVFV
GDTLFMPDVGTARCDFPGGDARTLYQSIRRLLDLPPQTRLYMCHDYPPAGREATCETTVAEQRRANIHVRDGVTEDDFVQ
MRTRRDATLAMPTLMLPSIQVNIRAGALPPAEPNGVRYLKIPLNAL

Sequences:

>Translated_286_residues
MPAQISTFFDSDTCTMTYVVHGGPGTPCAVIDSVLDYDPKSGRTRTGSADRVAAYIEANALRVEWLLETHAHADHLSAAP
YLRNRFGGRIAIGERIRVVQGVFKPIFNLEPSFRLDGSQFDHLFAADEVFRIGALEAKALSVPGHTPADMAYQVGDAVFV
GDTLFMPDVGTARCDFPGGDARTLYQSIRRLLDLPPQTRLYMCHDYPPAGREATCETTVAEQRRANIHVRDGVTEDDFVQ
MRTRRDATLAMPTLMLPSIQVNIRAGALPPAEPNGVRYLKIPLNAL
>Mature_285_residues
PAQISTFFDSDTCTMTYVVHGGPGTPCAVIDSVLDYDPKSGRTRTGSADRVAAYIEANALRVEWLLETHAHADHLSAAPY
LRNRFGGRIAIGERIRVVQGVFKPIFNLEPSFRLDGSQFDHLFAADEVFRIGALEAKALSVPGHTPADMAYQVGDAVFVG
DTLFMPDVGTARCDFPGGDARTLYQSIRRLLDLPPQTRLYMCHDYPPAGREATCETTVAEQRRANIHVRDGVTEDDFVQM
RTRRDATLAMPTLMLPSIQVNIRAGALPPAEPNGVRYLKIPLNAL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=272, Percent_Identity=27.2058823529412, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330176, Length=263, Percent_Identity=26.615969581749, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31460; Mature: 31329

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQISTFFDSDTCTMTYVVHGGPGTPCAVIDSVLDYDPKSGRTRTGSADRVAAYIEANA
CCCCCCEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEECCE
LRVEWLLETHAHADHLSAAPYLRNRFGGRIAIGERIRVVQGVFKPIFNLEPSFRLDGSQF
EEEEEEEHHCCCHHHCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCHH
DHLFAADEVFRIGALEAKALSVPGHTPADMAYQVGDAVFVGDTLFMPDVGTARCDFPGGD
HHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHCCCEEEECCEEECCCCCCCCCCCCCCC
ARTLYQSIRRLLDLPPQTRLYMCHDYPPAGREATCETTVAEQRRANIHVRDGVTEDDFVQ
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHHH
MRTRRDATLAMPTLMLPSIQVNIRAGALPPAEPNGVRYLKIPLNAL
HHHCCCCCEECCEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
PAQISTFFDSDTCTMTYVVHGGPGTPCAVIDSVLDYDPKSGRTRTGSADRVAAYIEANA
CCCCCEEECCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEECCE
LRVEWLLETHAHADHLSAAPYLRNRFGGRIAIGERIRVVQGVFKPIFNLEPSFRLDGSQF
EEEEEEEHHCCCHHHCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCEEECCCHH
DHLFAADEVFRIGALEAKALSVPGHTPADMAYQVGDAVFVGDTLFMPDVGTARCDFPGGD
HHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHCCCEEEECCEEECCCCCCCCCCCCCCC
ARTLYQSIRRLLDLPPQTRLYMCHDYPPAGREATCETTVAEQRRANIHVRDGVTEDDFVQ
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHHHH
MRTRRDATLAMPTLMLPSIQVNIRAGALPPAEPNGVRYLKIPLNAL
HHHCCCCCEECCEEECCCEEEEEEECCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]