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The map label for this gene is prpB [C]

Identifier: 17546167

GI number: 17546167

Start: 1550194

End: 1551033

Strand: Reverse

Name: prpB [C]

Synonym: RSc1448

Alternate gene names: 17546167

Gene position: 1551033-1550194 (Counterclockwise)

Preceding gene: 17546174

Following gene: 17546166

Centisome position: 41.73

GC content: 72.14

Gene sequence:

>840_bases
ATGCCGACCCAGACCGAAAAAGCCCAGGCCTTCCGCACCCTGCACGAACGCAGCGGCGCCTTCGTCATTCCCAACCCGTG
GGACCCGGGCTCGGCCCGCCTGCTGGCGGTGCTGGGCTTCGAGGCGCTCACCAGCACCAGCGCCGGCTTCGCGTTCTCGC
GCGGGCTGCCGGATTACGGCGCCGGCCGCGATGCCATCCTCGCGCACGTGGCGGACCTGGCCGCCGCCACCGACCTGCCC
GTGGCCGCCGACCTGGAGAACGGCTTCGGCGACGATCCCCAGACGGTGGCCGAGACCATCCGCCTGGCGGGCGCGACCGG
CATCGTCGGCGGTTCGATCGAAGATGCCACGGGCCGGGCCGACGCGCCCATCTATTCGCTTGAAGCCTCGGCCGAGCGGA
TACGGGCCGCCGTCGAAGCCGCCCGTTCGCTGTCCTTCCCCTTCACGCTCACCGCACGGGCGGAGAACCACCTGCACGGC
CGCAACGACCTGGCCGACACCATCCGCCGCCTGCAGGCCTACCAGGACGCGGGCGCCGATGTGCTCTACGCCCCCGGCCT
GAAGACGCATGAAGAAATCGCCACCGTGCTGCGCGAGGTCGATCGCCCCGTCAACGTGATGATGGGCTTTGCCGACGGCA
ACCTGAGCGTGGCCGAACTGGCGGCGCTGGGCGTCAAGCGCGTCAGCGTGGGCGGCGCCCTGGCCCGCGCGGCGCTGGGC
GCCTTCCTCCGCGCCGCCGAGGAACTCCGCGCCACGGGGACGTTCGCCTTCGCGCACGATGCCGCGGGCACGGCCAGGCT
CAACGGCCTGTTTGCGCCGTTTGCCCCGACGCTTGCCTGA

Upstream 100 bases:

>100_bases
TCGGCGACGCGATGTTCCGGGGCAACGACCGCCCGGACGACGCACTCGCCAGTGCCGCCGCGCGGCGTACCGCACCTCCC
CCGACACCCCTCGACCCACC

Downstream 100 bases:

>100_bases
ATCGCACCCCGGAACGGTACGACGCATTGATCGCCCAACGGCGATATCTTGCATTTATCGCCCCAAAGCGATAAATTACA
AATATCGTCTTGGGGTGATA

Product: hypothetical protein

Products: Pyruvate; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MPTQTEKAQAFRTLHERSGAFVIPNPWDPGSARLLAVLGFEALTSTSAGFAFSRGLPDYGAGRDAILAHVADLAAATDLP
VAADLENGFGDDPQTVAETIRLAGATGIVGGSIEDATGRADAPIYSLEASAERIRAAVEAARSLSFPFTLTARAENHLHG
RNDLADTIRRLQAYQDAGADVLYAPGLKTHEEIATVLREVDRPVNVMMGFADGNLSVAELAALGVKRVSVGGALARAALG
AFLRAAEELRATGTFAFAHDAAGTARLNGLFAPFAPTLA

Sequences:

>Translated_279_residues
MPTQTEKAQAFRTLHERSGAFVIPNPWDPGSARLLAVLGFEALTSTSAGFAFSRGLPDYGAGRDAILAHVADLAAATDLP
VAADLENGFGDDPQTVAETIRLAGATGIVGGSIEDATGRADAPIYSLEASAERIRAAVEAARSLSFPFTLTARAENHLHG
RNDLADTIRRLQAYQDAGADVLYAPGLKTHEEIATVLREVDRPVNVMMGFADGNLSVAELAALGVKRVSVGGALARAALG
AFLRAAEELRATGTFAFAHDAAGTARLNGLFAPFAPTLA
>Mature_278_residues
PTQTEKAQAFRTLHERSGAFVIPNPWDPGSARLLAVLGFEALTSTSAGFAFSRGLPDYGAGRDAILAHVADLAAATDLPV
AADLENGFGDDPQTVAETIRLAGATGIVGGSIEDATGRADAPIYSLEASAERIRAAVEAARSLSFPFTLTARAENHLHGR
NDLADTIRRLQAYQDAGADVLYAPGLKTHEEIATVLREVDRPVNVMMGFADGNLSVAELAALGVKRVSVGGALARAALGA
FLRAAEELRATGTFAFAHDAAGTARLNGLFAPFAPTLA

Specific function: Catalyzes The Formation Of Pyruvate And Succinate From 2-Methylisocitrate (By Similarity). [C]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR015813 [H]

Pfam domain/function: NA

EC number: 4.1.3.30 [C]

Molecular weight: Translated: 29023; Mature: 28892

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTQTEKAQAFRTLHERSGAFVIPNPWDPGSARLLAVLGFEALTSTSAGFAFSRGLPDYG
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
AGRDAILAHVADLAAATDLPVAADLENGFGDDPQTVAETIRLAGATGIVGGSIEDATGRA
CCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DAPIYSLEASAERIRAAVEAARSLSFPFTLTARAENHLHGRNDLADTIRRLQAYQDAGAD
CCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
VLYAPGLKTHEEIATVLREVDRPVNVMMGFADGNLSVAELAALGVKRVSVGGALARAALG
EEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLRAAEELRATGTFAFAHDAAGTARLNGLFAPFAPTLA
HHHHHHHHHHHCCCEEEECCCCCHHHHCCEECCCCCCCC
>Mature Secondary Structure 
PTQTEKAQAFRTLHERSGAFVIPNPWDPGSARLLAVLGFEALTSTSAGFAFSRGLPDYG
CCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
AGRDAILAHVADLAAATDLPVAADLENGFGDDPQTVAETIRLAGATGIVGGSIEDATGRA
CCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DAPIYSLEASAERIRAAVEAARSLSFPFTLTARAENHLHGRNDLADTIRRLQAYQDAGAD
CCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
VLYAPGLKTHEEIATVLREVDRPVNVMMGFADGNLSVAELAALGVKRVSVGGALARAALG
EEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AFLRAAEELRATGTFAFAHDAAGTARLNGLFAPFAPTLA
HHHHHHHHHHHCCCEEEECCCCCHHHHCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: methylisocitrate [C]

Specific reaction: methylisocitrate <==> Pyruvate + Succinate [C]

General reaction: Elimination [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]