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The map label for this gene is cysU [H]

Identifier: 17546064

GI number: 17546064

Start: 1431550

End: 1432464

Strand: Direct

Name: cysU [H]

Synonym: RSc1345

Alternate gene names: 17546064

Gene position: 1431550-1432464 (Clockwise)

Preceding gene: 17546063

Following gene: 17546065

Centisome position: 38.52

GC content: 68.63

Gene sequence:

>915_bases
ATGAGCCTGTTCTCTCCGTTCTCTTCCGCCCGCCGGCGCAAGCCTGCCAACGTGCTGCCCGGCTTCGGGCTGGCGCTGGG
CTTTTCCCTGCTGTACCTGGCGCTGATCGTGCTGATCCCGCTGTCGGCCACGGTGCTCAAGACCGTGTCCATGACGTGGG
ACGCCTTCTGGAGTACGGTGACCGCGCCGCGCGTGGTGGCTTCCTACCAGCTGACCTTCGGCGCCTCGCTGCTGGCGGCG
GCGCTCAACCTGGTGTTCGGGCTGATCGTGGCCTGGGTTCTGGTGCGCTACCGTTTTCCGGGCAAGCGGCTGGTGGATGC
GCTGGTCGACCTGCCGTTCGCGCTGCCCACGGCGGTGGCCGGCATCGCGCTTACCGCGCTGTACGCGCCCAACGGCTGGA
TCGGGTCGCGGCTGGAGCCGCTGGGGTTGAAAGTCGCGTTCACGCCGCTGGGCATCGTGGTGGCGCTCACCTTCATCGGC
CTGCCGTTCGTGGTGCGCACGGTGCAGCCGGTGCTCGAAGACCTGGAGGCCGAACTGGAAGAGGCTGCCGCCAGCCTGGG
CGCCACGCGCTGGCAAACGTTCCTCCGCGTGATCCTGCCGACCCTGCTGCCGACGCTGCTGACCGGCTTCGCGCTGGCCT
TCGCGCGTGCCACGGGCGAGTACGGCTCGGTCATCTTCATCGCCGGCAACATGCCGATGATCTCCGAGATCACGCCGCTG
ATGATCTATTCCAAGCTGGAGCAGTTCGACTACGCGGGCGCCACCGCCATCGCCGTGGTCATGCTGGCGATCTCGTTCGC
GCTGCTGCTGGTGATCAACCTGCTGCAGGCCTGGACGCGCCGGCGCGGCAGCCGCAACGACGCCATCGAGCGTCCCGCCC
AACCCTTGGCCGCCGCCGGCGCCGCAGGAGCTTGA

Upstream 100 bases:

>100_bases
ACATGCGCAAATATTCGTTTTCTTCATAAGAAGTGCTCGCCACAATCGGTTCATCTGCATCCCGGCCGCAGTTTCGCGGC
CTTTTTTATCGGTTGCGCTG

Downstream 100 bases:

>100_bases
CGTGGCCGCGACCGTTTCCCGCCAACCCGGCCAGGCGCCGGCGGCTGCCCGGCGCGGTGCCACCGCAGAAGCCGCGTGGG
TGCGCGCGGCGCTGATCCTG

Product: sulfate transport ABC transporter protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLFSPFSSARRRKPANVLPGFGLALGFSLLYLALIVLIPLSATVLKTVSMTWDAFWSTVTAPRVVASYQLTFGASLLAA
ALNLVFGLIVAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALTALYAPNGWIGSRLEPLGLKVAFTPLGIVVALTFIG
LPFVVRTVQPVLEDLEAELEEAAASLGATRWQTFLRVILPTLLPTLLTGFALAFARATGEYGSVIFIAGNMPMISEITPL
MIYSKLEQFDYAGATAIAVVMLAISFALLLVINLLQAWTRRRGSRNDAIERPAQPLAAAGAAGA

Sequences:

>Translated_304_residues
MSLFSPFSSARRRKPANVLPGFGLALGFSLLYLALIVLIPLSATVLKTVSMTWDAFWSTVTAPRVVASYQLTFGASLLAA
ALNLVFGLIVAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALTALYAPNGWIGSRLEPLGLKVAFTPLGIVVALTFIG
LPFVVRTVQPVLEDLEAELEEAAASLGATRWQTFLRVILPTLLPTLLTGFALAFARATGEYGSVIFIAGNMPMISEITPL
MIYSKLEQFDYAGATAIAVVMLAISFALLLVINLLQAWTRRRGSRNDAIERPAQPLAAAGAAGA
>Mature_303_residues
SLFSPFSSARRRKPANVLPGFGLALGFSLLYLALIVLIPLSATVLKTVSMTWDAFWSTVTAPRVVASYQLTFGASLLAAA
LNLVFGLIVAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALTALYAPNGWIGSRLEPLGLKVAFTPLGIVVALTFIGL
PFVVRTVQPVLEDLEAELEEAAASLGATRWQTFLRVILPTLLPTLLTGFALAFARATGEYGSVIFIAGNMPMISEITPLM
IYSKLEQFDYAGATAIAVVMLAISFALLLVINLLQAWTRRRGSRNDAIERPAQPLAAAGAAGA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=276, Percent_Identity=54.3478260869565, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI87082099, Length=269, Percent_Identity=31.2267657992565, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786980, Length=217, Percent_Identity=35.9447004608295, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786254, Length=224, Percent_Identity=29.9107142857143, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787368, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787369, Length=155, Percent_Identity=29.6774193548387, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32491; Mature: 32360

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSPFSSARRRKPANVLPGFGLALGFSLLYLALIVLIPLSATVLKTVSMTWDAFWSTV
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAPRVVASYQLTFGASLLAAALNLVFGLIVAWVLVRYRFPGKRLVDALVDLPFALPTAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
GIALTALYAPNGWIGSRLEPLGLKVAFTPLGIVVALTFIGLPFVVRTVQPVLEDLEAELE
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAASLGATRWQTFLRVILPTLLPTLLTGFALAFARATGEYGSVIFIAGNMPMISEITPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
MIYSKLEQFDYAGATAIAVVMLAISFALLLVINLLQAWTRRRGSRNDAIERPAQPLAAAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCC
AAGA
CCCC
>Mature Secondary Structure 
SLFSPFSSARRRKPANVLPGFGLALGFSLLYLALIVLIPLSATVLKTVSMTWDAFWSTV
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAPRVVASYQLTFGASLLAAALNLVFGLIVAWVLVRYRFPGKRLVDALVDLPFALPTAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
GIALTALYAPNGWIGSRLEPLGLKVAFTPLGIVVALTFIGLPFVVRTVQPVLEDLEAELE
HHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAASLGATRWQTFLRVILPTLLPTLLTGFALAFARATGEYGSVIFIAGNMPMISEITPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
MIYSKLEQFDYAGATAIAVVMLAISFALLLVINLLQAWTRRRGSRNDAIERPAQPLAAAG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCC
AAGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]