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The map label for this gene is yfbQ [H]

Identifier: 17546045

GI number: 17546045

Start: 1411206

End: 1412447

Strand: Direct

Name: yfbQ [H]

Synonym: RSc1326

Alternate gene names: 17546045

Gene position: 1411206-1412447 (Clockwise)

Preceding gene: 17546032

Following gene: 17546046

Centisome position: 37.97

GC content: 64.33

Gene sequence:

>1242_bases
GTGAAAACGATCCAGAAATCCGCCAAGCTCAACAACGTCTGCTATGACATCCGCGGCCCCGTGCTGGAGAAGGCCAAGCA
GATGGAGGAAGAGGGCCACCAGATCATCAAGCTGAACATCGGCAACCTGGCCCCGTTCGGCTTCGATGCCCCGGAAGAGA
TCCAGCAGGACATGATCCGCAACCTGCCCAACTCGGCCGGCTACTCGGATTCCAAGGGCATCTTCGCGGCGCGCAAGGCG
GTGATGCACTATACGCAGCAGCAGGGCATCAAGAACGTCACGCTGGACGACATCTACCTGGGCAACGGCGCCTCCGAGCT
GATCGCGCTGGCCACCAACGCGCTGCTCGACGCCGGCGACGAACTGCTGCTGCCCGCACCCGATTACCCGCTGTGGACCG
CCATGACCAGCCTGTCGGGCGGCACGCCGGTGCATTACCTGTGCGACGAGTCCAACGGCTGGATGCCCGACCTGGACGAC
ATCCGCGCCAAGATCACGCCCAACACCAAGGGCATCGTCGTCATCAACCCGAACAATCCGACCGGTGCGCTGTATTCGGA
CGCGCTGCTGCACGACATCATCGCCATCGCACGCGAGCACGGGCTGGTGATCTTTGCCGACGAGGTGTACGACAAGGTGC
TGTTCGACGACAATCGGCACACCGCGATGGCCTCGCTGTCGGAGGATGTGCTGACCGTCACGTTCAACAGCCTGTCCAAG
AGCTACCGCTCGTGCGGCTACCGCGCGGGCTGGATGGTGGTGTCGGGCGACAAGCGTCCGGCCAAGGACTACATCGAAGG
CCTGAACATGCTGTCGTCGATGCGCCTGTGCGCCAATGTGCCGGGGCAGTGGGCGATCCAGACGGCGCTGGGCGGCTATC
AGAGCATCAACGACCTGGTGGCGCCGGGCGGCCGCATGCGCCGCCAGCGCGACCTGGCCTACGAACTGATCACCGCCATT
CCCGGCGTGAGCTGCGTCAAGCCGAAGGCGGCGCTGTACATGTTCCCGCGCCTGGATCCGTCGGTGTACCCGATCGACGA
CGATCAGACCTTCATTCGCCAACTGCTGGAGGAAGAGCGCGTGCTGCTGGTGCAGGGCACGGGCTTCAACTGGCATTCGC
CGGACCACTTCCGCATCGTCTTCCTGCCGCACGAGGACGACCTGCGCGAGGCCATCGGCCGAATTGCGCGCTTCCTGGAG
CGGTACCGTCAGCGTCACGGTACTGGCATCCGGGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGCCCGCGGGTGCGCCATCGCTGCCGCACCATGATCGCGGCCCCCGCGTCACCCAGATTCCAGCCACGCCCAACACCA
AGCCAGCCTCGACGCCGCCC

Downstream 100 bases:

>100_bases
ACTCGGTCATCCGCCAGATCCGTCGTTGCGGGGCAGACCGAAGTGTCTGCCCTGTCCGTTTTTTGCCTTTCCGCTTTTAC
AACACGTCTCATGAAACCCA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEEGHQIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYTQQQGIKNVTLDDIYLGNGASELIALATNALLDAGDELLLPAPDYPLWTAMTSLSGGTPVHYLCDESNGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDALLHDIIAIAREHGLVIFADEVYDKVLFDDNRHTAMASLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAPGGRMRRQRDLAYELITAI
PGVSCVKPKAALYMFPRLDPSVYPIDDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRIARFLE
RYRQRHGTGIRAA

Sequences:

>Translated_413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEEGHQIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYTQQQGIKNVTLDDIYLGNGASELIALATNALLDAGDELLLPAPDYPLWTAMTSLSGGTPVHYLCDESNGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDALLHDIIAIAREHGLVIFADEVYDKVLFDDNRHTAMASLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAPGGRMRRQRDLAYELITAI
PGVSCVKPKAALYMFPRLDPSVYPIDDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRIARFLE
RYRQRHGTGIRAA
>Mature_413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEEGHQIIKLNIGNLAPFGFDAPEEIQQDMIRNLPNSAGYSDSKGIFAARKA
VMHYTQQQGIKNVTLDDIYLGNGASELIALATNALLDAGDELLLPAPDYPLWTAMTSLSGGTPVHYLCDESNGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDALLHDIIAIAREHGLVIFADEVYDKVLFDDNRHTAMASLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAPGGRMRRQRDLAYELITAI
PGVSCVKPKAALYMFPRLDPSVYPIDDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRIARFLE
RYRQRHGTGIRAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=470, Percent_Identity=28.7234042553192, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI215599424, Length=382, Percent_Identity=31.413612565445, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI4507369, Length=391, Percent_Identity=27.3657289002558, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI4885351, Length=447, Percent_Identity=26.3982102908277, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=29.0697674418605, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=29.0697674418605, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=26.9461077844311, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=26.9461077844311, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI169881281, Length=145, Percent_Identity=28.2758620689655, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI187936925, Length=375, Percent_Identity=22.4, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=375, Percent_Identity=22.4, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=64.1089108910891, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=26.1455525606469, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=24.4031830238727, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790797, Length=200, Percent_Identity=27, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=28.4960422163588, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=474, Percent_Identity=25.1054852320675, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=309, Percent_Identity=25.8899676375405, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=309, Percent_Identity=25.8899676375405, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=27.4576271186441, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=210, Percent_Identity=27.1428571428571, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=383, Percent_Identity=30.0261096605744, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323118, Length=393, Percent_Identity=27.735368956743, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322401, Length=349, Percent_Identity=24.3553008595989, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI18859735, Length=393, Percent_Identity=27.9898218829517, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI45551451, Length=468, Percent_Identity=25.6410256410256, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641770, Length=468, Percent_Identity=25.6410256410256, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641760, Length=468, Percent_Identity=25.6410256410256, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641768, Length=468, Percent_Identity=25.6410256410256, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641766, Length=468, Percent_Identity=25.6410256410256, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641764, Length=468, Percent_Identity=25.6410256410256, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45953; Mature: 45953

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEEGHQIIKLNIGNLAPFGFDAPEEIQQDMIR
CCCHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYTQQQGIKNVTLDDIYLGNGASELIALATNALLDAGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
ELLLPAPDYPLWTAMTSLSGGTPVHYLCDESNGWMPDLDDIRAKITPNTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCEEEECCCCCEEEEECCCCC
TGALYSDALLHDIIAIAREHGLVIFADEVYDKVLFDDNRHTAMASLSEDVLTVTFNSLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHCCCCEEEEHHHHHH
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLV
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHH
APGGRMRRQRDLAYELITAIPGVSCVKPKAALYMFPRLDPSVYPIDDDQTFIRQLLEEER
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCEEECCCCHHHHHHHHCCCC
VLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRIARFLERYRQRHGTGIRAA
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEEGHQIIKLNIGNLAPFGFDAPEEIQQDMIR
CCCHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYTQQQGIKNVTLDDIYLGNGASELIALATNALLDAGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
ELLLPAPDYPLWTAMTSLSGGTPVHYLCDESNGWMPDLDDIRAKITPNTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCEEEECCCCCEEEEECCCCC
TGALYSDALLHDIIAIAREHGLVIFADEVYDKVLFDDNRHTAMASLSEDVLTVTFNSLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHCCCCEEEEHHHHHH
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLV
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHH
APGGRMRRQRDLAYELITAIPGVSCVKPKAALYMFPRLDPSVYPIDDDQTFIRQLLEEER
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCEEECCCCHHHHHHHHCCCC
VLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRIARFLERYRQRHGTGIRAA
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]