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The map label for this gene is murR [H]

Identifier: 17545968

GI number: 17545968

Start: 1324592

End: 1325500

Strand: Direct

Name: murR [H]

Synonym: RSc1249

Alternate gene names: 17545968

Gene position: 1324592-1325500 (Clockwise)

Preceding gene: 17545967

Following gene: 17545970

Centisome position: 35.64

GC content: 65.57

Gene sequence:

>909_bases
ATGTCGGGACTGTCCAAATCGCGTCATCCGATGAATCCATCCGAGAAGCCTCCCGCCACCATCGATGCGTTCCTGCAGCG
CCTCACGCAGGAATACGACGGGCTGAGCAAGCGCCTCAAGCTGATCGCCCGCCATGTCGAGACCCATCGAGACCACCTGG
GCCTGGAGGGCATTCAGTCGATGGCCGCCCAGTGCGGCGTCCAGCCGTCGGCCGTGGTGCGCTTCGCCCAGCATTTCGGC
TTCTCGGGCTTTTCCGAGATGCAGCGGCTGTTTCGCGACGGGCTCGTGCAGCAGATCGCGCCCGGGCGGGATTACAACCT
TCGCTTGCGCGAGGTGATCGAGTCGGGTTCTGCGAGCCTGCAGCCCGAGCAGATCGTCGATGAGTTCATCAAGGGCAGCA
TTGCCGGCATGCAGCAATTGCGCCAGGCGCTCGATCAGAAAGCCTTTGCGCAGGCGGTCGACATGCTGGCGGACACGCAG
GCGATCTGGATTGCCGGCTCGCGCCGCTCGTTTCCTGTCGCCGTGTACCTGGACTACGCGCTGCAGCACACGGACAAGCG
GGTCGGCCTGTTCAGCGCGCTGGGCAGCATGCACCTGGGGCAGATCCGCTCGGTGCGCGAGGGCGATGTGCTGATCGCGA
TCTCCTTCATGCCCAATGCGGAGGAGACCATCGAGGTGGCGCAGCAGGCCAGGCAACGGGGCGCGCGGATGATCGCCGTG
ACCGACAGCCGCATGAGCCCGCTTGCGCGCGAGGCCGAGGTCACGCTCGTGGTGCAGGACAGCACCACCTTCGGTTTCCG
TGCGCTGACGGCGACGATGGGGCTCGCGCAAAGCCTGTTCATCGCGCTGGCGTATCGGCTTGAACTCTCCTCGGCCGGCG
GCGAGCACGAGAAGGACGTGATGGCCTGA

Upstream 100 bases:

>100_bases
TGCCGGCATGGTTTGAAGAACCGGCCGCCGCGGGTCTAAAATGGGCCTTCGCATTGTTTCCTGATACGCGTTGGGCTGGT
TTCCCGACTGAGCGAACCGA

Downstream 100 bases:

>100_bases
GGCGCCGCGATCGGCGCGCTGAAGCCTGGGCTTACAGCTTCTTCATCAGCACCATCGACCGCCGCTGCCAGTTGTACAGC
TTGCGGCGGTCTTCCGGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSGLSKSRHPMNPSEKPPATIDAFLQRLTQEYDGLSKRLKLIARHVETHRDHLGLEGIQSMAAQCGVQPSAVVRFAQHFG
FSGFSEMQRLFRDGLVQQIAPGRDYNLRLREVIESGSASLQPEQIVDEFIKGSIAGMQQLRQALDQKAFAQAVDMLADTQ
AIWIAGSRRSFPVAVYLDYALQHTDKRVGLFSALGSMHLGQIRSVREGDVLIAISFMPNAEETIEVAQQARQRGARMIAV
TDSRMSPLAREAEVTLVVQDSTTFGFRALTATMGLAQSLFIALAYRLELSSAGGEHEKDVMA

Sequences:

>Translated_302_residues
MSGLSKSRHPMNPSEKPPATIDAFLQRLTQEYDGLSKRLKLIARHVETHRDHLGLEGIQSMAAQCGVQPSAVVRFAQHFG
FSGFSEMQRLFRDGLVQQIAPGRDYNLRLREVIESGSASLQPEQIVDEFIKGSIAGMQQLRQALDQKAFAQAVDMLADTQ
AIWIAGSRRSFPVAVYLDYALQHTDKRVGLFSALGSMHLGQIRSVREGDVLIAISFMPNAEETIEVAQQARQRGARMIAV
TDSRMSPLAREAEVTLVVQDSTTFGFRALTATMGLAQSLFIALAYRLELSSAGGEHEKDVMA
>Mature_301_residues
SGLSKSRHPMNPSEKPPATIDAFLQRLTQEYDGLSKRLKLIARHVETHRDHLGLEGIQSMAAQCGVQPSAVVRFAQHFGF
SGFSEMQRLFRDGLVQQIAPGRDYNLRLREVIESGSASLQPEQIVDEFIKGSIAGMQQLRQALDQKAFAQAVDMLADTQA
IWIAGSRRSFPVAVYLDYALQHTDKRVGLFSALGSMHLGQIRSVREGDVLIAISFMPNAEETIEVAQQARQRGARMIAVT
DSRMSPLAREAEVTLVVQDSTTFGFRALTATMGLAQSLFIALAYRLELSSAGGEHEKDVMA

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33291; Mature: 33159

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLSKSRHPMNPSEKPPATIDAFLQRLTQEYDGLSKRLKLIARHVETHRDHLGLEGIQS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MAAQCGVQPSAVVRFAQHFGFSGFSEMQRLFRDGLVQQIAPGRDYNLRLREVIESGSASL
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
QPEQIVDEFIKGSIAGMQQLRQALDQKAFAQAVDMLADTQAIWIAGSRRSFPVAVYLDYA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEHHHH
LQHTDKRVGLFSALGSMHLGQIRSVREGDVLIAISFMPNAEETIEVAQQARQRGARMIAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
TDSRMSPLAREAEVTLVVQDSTTFGFRALTATMGLAQSLFIALAYRLELSSAGGEHEKDV
ECCHHCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MA
CC
>Mature Secondary Structure 
SGLSKSRHPMNPSEKPPATIDAFLQRLTQEYDGLSKRLKLIARHVETHRDHLGLEGIQS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MAAQCGVQPSAVVRFAQHFGFSGFSEMQRLFRDGLVQQIAPGRDYNLRLREVIESGSASL
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
QPEQIVDEFIKGSIAGMQQLRQALDQKAFAQAVDMLADTQAIWIAGSRRSFPVAVYLDYA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEHHHH
LQHTDKRVGLFSALGSMHLGQIRSVREGDVLIAISFMPNAEETIEVAQQARQRGARMIAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
TDSRMSPLAREAEVTLVVQDSTTFGFRALTATMGLAQSLFIALAYRLELSSAGGEHEKDV
ECCHHCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA