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The map label for this gene is qor [H]

Identifier: 17545922

GI number: 17545922

Start: 1271737

End: 1272711

Strand: Reverse

Name: qor [H]

Synonym: RSc1203

Alternate gene names: 17545922

Gene position: 1272711-1271737 (Counterclockwise)

Preceding gene: 17545927

Following gene: 17545914

Centisome position: 34.25

GC content: 68.51

Gene sequence:

>975_bases
ATGAAAGCCGTCGTCTGCAAGACCTGGGGTCCGCCCGAATCGCTGGTGATCGAAACCCTGCCGGACCCCGTGCCCGGCGC
CGGCGAGGTCGTCATCGACGTGAAGGCCGCCGGCGTGAATTTCCCCGATGTGCTGATCATCCAGAACCAATACCAGTTCA
AGCCCGAACTGCCCTTCACGCCGGGCTCGGAGCTGGCCGGCGTGGTGCGCGCGGTGGGCGATGGCGTCTCGCACGTGAAA
GCGGGCGACCCCGTGATCGCGTTCCTCGGCCAGGGTGCGTTCGCCTCGCAGGTGAAGGCGCCGGCCAAGATGGTGATGCC
GATGCCGCCGGGCATGGCGTTCGACACGGCAGCCGCGTTCACACTCACCTATGGCACGTCGCACCACGCGGTGGTCGACC
GCGGACAACTGCGGCCGGGCGAGACCATGCTGGTGCTGGGCGCGGCGGGCGGCGTGGGGCTGGCGGCGATCGAGATCGGC
AAGGCGATCGGCGCCCGCGTGATCGCGGCGGCGTCGAGCGACGAGAAGCTGGCCGTCTGCAGGGAGCACGGCGCCGATGC
GCTGATCAACTACGCCGCGGAAGACCTGCGCGAGCGCATCAAGGCGCTGACCGACGGCAAGGGCCCGGACGTCATCTACG
ACCCGGTCGGCGGGATCTATGCGGAGCCGGCCTTCCGCTCGATCGCCTGGCGGGGCCGCTACCTCGTGGTGGGCTTTGCC
AACGGCGAGATTCCCAAGATGCCGCTGAACCTCGCGCTGCTCAAGGGAGCGTCGCTGGTCGGCGTGTTCTGGGGCGACTT
CGCCCGCCGCGAGCCGAAGGCGAATCTCGCCAACATGATGCAGATGCTGGGCTGGTTGCAGGAAGGCAAGATCCGCCCGC
ATATCTCGGCGCGCTATCCGCTGGAGCGGACCGCGCAGGCGCTGCTCGACATGGCGGCACGCAAGGTGACAGGCAAGGTG
GTGATCCAGCCGTAA

Upstream 100 bases:

>100_bases
TGCGCGGAAATCGAATCGAACGACCGTGCTTTTATTCGGTTACACTGCTCGGCATTCACGGATGATTCGTCGTCGCAGCA
CACACCAATCAGGAGACAAG

Downstream 100 bases:

>100_bases
GCGTCGTCAGCGTTTGGCAAGAAAAAGCCGCGCGGGCAGCAGGCCGGCGCGGCTTTTTCATTGGCGTGGCGGACCGCTCA
GGCGGCTTCTTCCAGTGTCG

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKAVVCKTWGPPESLVIETLPDPVPGAGEVVIDVKAAGVNFPDVLIIQNQYQFKPELPFTPGSELAGVVRAVGDGVSHVK
AGDPVIAFLGQGAFASQVKAPAKMVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLRPGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCREHGADALINYAAEDLRERIKALTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGDFARREPKANLANMMQMLGWLQEGKIRPHISARYPLERTAQALLDMAARKVTGKV
VIQP

Sequences:

>Translated_324_residues
MKAVVCKTWGPPESLVIETLPDPVPGAGEVVIDVKAAGVNFPDVLIIQNQYQFKPELPFTPGSELAGVVRAVGDGVSHVK
AGDPVIAFLGQGAFASQVKAPAKMVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLRPGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCREHGADALINYAAEDLRERIKALTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGDFARREPKANLANMMQMLGWLQEGKIRPHISARYPLERTAQALLDMAARKVTGKV
VIQP
>Mature_324_residues
MKAVVCKTWGPPESLVIETLPDPVPGAGEVVIDVKAAGVNFPDVLIIQNQYQFKPELPFTPGSELAGVVRAVGDGVSHVK
AGDPVIAFLGQGAFASQVKAPAKMVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLRPGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCREHGADALINYAAEDLRERIKALTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGDFARREPKANLANMMQMLGWLQEGKIRPHISARYPLERTAQALLDMAARKVTGKV
VIQP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=32.3899371069182, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.8042813455657, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.8042813455657, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI22538446, Length=337, Percent_Identity=31.7507418397626, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI22538444, Length=337, Percent_Identity=31.7507418397626, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.9694189602446, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=27.8735632183908, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI28557745, Length=321, Percent_Identity=29.595015576324, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41872631, Length=305, Percent_Identity=26.2295081967213, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI47519420, Length=333, Percent_Identity=29.1291291291291, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67078404, Length=290, Percent_Identity=26.551724137931, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI67078406, Length=282, Percent_Identity=26.9503546099291, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=29.1005291005291, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790485, Length=322, Percent_Identity=32.9192546583851, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787863, Length=335, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788073, Length=267, Percent_Identity=26.9662921348315, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI226510941, Length=343, Percent_Identity=25.9475218658892, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=27.82874617737, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17536829, Length=319, Percent_Identity=26.9592476489028, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=30.2752293577982, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24581345, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920632, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221330659, Length=255, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550423, Length=220, Percent_Identity=26.8181818181818, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34254; Mature: 34254

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVCKTWGPPESLVIETLPDPVPGAGEVVIDVKAAGVNFPDVLIIQNQYQFKPELPFT
CCEEEECCCCCCHHEEEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSELAGVVRAVGDGVSHVKAGDPVIAFLGQGAFASQVKAPAKMVMPMPPGMAFDTAAAF
CCHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCEEE
TLTYGTSHHAVVDRGQLRPGETMLVLGAAGGVGLAAIEIGKAIGARVIAAASSDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHH
REHGADALINYAAEDLRERIKALTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKMPLNLALLKGASLVGVFWGDFARREPKANLANMMQMLGWLQEGKIRPHISARYP
CCCCCCCCCEEEEECCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
LERTAQALLDMAARKVTGKVVIQP
HHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MKAVVCKTWGPPESLVIETLPDPVPGAGEVVIDVKAAGVNFPDVLIIQNQYQFKPELPFT
CCEEEECCCCCCHHEEEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSELAGVVRAVGDGVSHVKAGDPVIAFLGQGAFASQVKAPAKMVMPMPPGMAFDTAAAF
CCHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCEEE
TLTYGTSHHAVVDRGQLRPGETMLVLGAAGGVGLAAIEIGKAIGARVIAAASSDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHH
REHGADALINYAAEDLRERIKALTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKMPLNLALLKGASLVGVFWGDFARREPKANLANMMQMLGWLQEGKIRPHISARYP
CCCCCCCCCEEEEECCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
LERTAQALLDMAARKVTGKVVIQP
HHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]