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The map label for this gene is slyD [H]

Identifier: 17545868

GI number: 17545868

Start: 1205573

End: 1206097

Strand: Direct

Name: slyD [H]

Synonym: RSc1149

Alternate gene names: 17545868

Gene position: 1205573-1206097 (Clockwise)

Preceding gene: 17545866

Following gene: 17545872

Centisome position: 32.44

GC content: 63.05

Gene sequence:

>525_bases
TTGAAAATCGCGAAGAATACCGTGGTGTCGGTGGCTTACAAACTGTCCGACGCGCAGGGCAACGTCATCGAGGAATCCGA
TGAGCCGATGGTGTATTTGCACGGCGGCTATGATGGCACGTTCCCCAAGATCGAGGAAGCGCTGGACGGCCATGAGCAAG
GCTTCGAGACGAAGCTGCAGCTGGAGCCGGACGACGCCTTCGGCGAATACGACCAGGAGCTGATCAAGATCGAGCCGCGT
GACCGTTTCCCCGAGCCGCTGGAAGTCGGCATGCAGTTCGAGGGCGTGCCGGAGGATGGCGATGACGAAGACGCCATCAT
CTACACCGTCACCGATGTGGCCGAAGACAAGGTCGTGCTGGACGGCAACCACCCGCTGGCCGGCATGGCGCTGCGCTTCG
ATCTGCGCGTGACCGACGTGCGCGAGGCCACCGCCGAGGAGATCGAGCACGGGCACGTGCACGGCGAGAACGGTCTCGAG
GTGGCCGATGAAGACGATGAGGAGCCGCCGCGCACGCTGCACTGA

Upstream 100 bases:

>100_bases
GACAGCCCGCCCAGCAACTGCGCCGGACGCCCCGCCGCCAGGCCGGGTTGGACACCGCGGGCGGCGGCGTATAATGGGAG
TTCGTTCATGGAGTGCGCAA

Downstream 100 bases:

>100_bases
CAGATCGGTGTGCTGAGAGGTAACGCAATGGAACGGGAGCTTCGGCTCCCGTTTTCATTGCTGCGGCGTGGATGGCGCGA
TGTCGCTGGCCAGGCGGCGG

Product: fkbp-type peptidyl-prolyl cis-trans isomerase (rotamase) protein

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKIAKNTVVSVAYKLSDAQGNVIEESDEPMVYLHGGYDGTFPKIEEALDGHEQGFETKLQLEPDDAFGEYDQELIKIEPR
DRFPEPLEVGMQFEGVPEDGDDEDAIIYTVTDVAEDKVVLDGNHPLAGMALRFDLRVTDVREATAEEIEHGHVHGENGLE
VADEDDEEPPRTLH

Sequences:

>Translated_174_residues
MKIAKNTVVSVAYKLSDAQGNVIEESDEPMVYLHGGYDGTFPKIEEALDGHEQGFETKLQLEPDDAFGEYDQELIKIEPR
DRFPEPLEVGMQFEGVPEDGDDEDAIIYTVTDVAEDKVVLDGNHPLAGMALRFDLRVTDVREATAEEIEHGHVHGENGLE
VADEDDEEPPRTLH
>Mature_174_residues
MKIAKNTVVSVAYKLSDAQGNVIEESDEPMVYLHGGYDGTFPKIEEALDGHEQGFETKLQLEPDDAFGEYDQELIKIEPR
DRFPEPLEVGMQFEGVPEDGDDEDAIIYTVTDVAEDKVVLDGNHPLAGMALRFDLRVTDVREATAEEIEHGHVHGENGLE
VADEDDEEPPRTLH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=152, Percent_Identity=39.4736842105263, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19405; Mature: 19405

Theoretical pI: Translated: 3.91; Mature: 3.91

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAKNTVVSVAYKLSDAQGNVIEESDEPMVYLHGGYDGTFPKIEEALDGHEQGFETKLQ
CCCCCCCEEEEEEEECCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEEE
LEPDDAFGEYDQELIKIEPRDRFPEPLEVGMQFEGVPEDGDDEDAIIYTVTDVAEDKVVL
ECCCCCCCCCCCEEEEECCCCCCCCHHHCCEEECCCCCCCCCCCEEEEEEECCCCCEEEE
DGNHPLAGMALRFDLRVTDVREATAEEIEHGHVHGENGLEVADEDDEEPPRTLH
ECCCCCEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MKIAKNTVVSVAYKLSDAQGNVIEESDEPMVYLHGGYDGTFPKIEEALDGHEQGFETKLQ
CCCCCCCEEEEEEEECCCCCCEEECCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCEEEE
LEPDDAFGEYDQELIKIEPRDRFPEPLEVGMQFEGVPEDGDDEDAIIYTVTDVAEDKVVL
ECCCCCCCCCCCEEEEECCCCCCCCHHHCCEEECCCCCCCCCCCEEEEEEECCCCCEEEE
DGNHPLAGMALRFDLRVTDVREATAEEIEHGHVHGENGLEVADEDDEEPPRTLH
ECCCCCEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]