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The map label for this gene is folB2

Identifier: 17545824

GI number: 17545824

Start: 1162782

End: 1163228

Strand: Direct

Name: folB2

Synonym: RSc1105

Alternate gene names: NA

Gene position: 1162782-1163228 (Clockwise)

Preceding gene: 17545823

Following gene: 17545826

Centisome position: 31.29

GC content: 68.23

Gene sequence:

>447_bases
ATGAAGCCGATCGACCCCCCTTTCAGTGACCCGCTCGCAGCGCTCGATCTGTCGCGCCTTCCGGGGCGGGGCTGGAGCGT
GTTCGTCGATGCGTTGACCGTGCCCGTGCGGATCGGCATCCATCCGCACGAGCATGGCGCCCCGCAGCCGATCGTGATCG
ACGCGCACCTCGGCTACGGCTGCGAACCGCGCGAAGACGGCGACTGGATCGACTACGACGGCTATTGCACGCGGGTCACG
GCGTTTCTCTCTGGCAAGCCGCATACGCGCCTGCTGGAGACGCTGGCAGCCGAGATCGCGGAGTGGTCGTTTCGCGAATG
GCCGGCGCTCGGCTTGCTGACCCTCGCCGTGCATAAGCCGAAGATCCGGCCCGGCACGCAACGCGTCGGCGTTGCGCTCG
AGTGGACCCGGGCCGATTACCTGCGGCGCTGCGGGAAGGTGGCCTGA

Upstream 100 bases:

>100_bases
TGATCCCGATCGGCAACGACACGTACGAGATCGTCGTGCGCCGCAGCTTCGCCGACTATTTTGTCCGCATCATGCTCGAT
GCGGCCACGCCATTGACATC

Downstream 100 bases:

>100_bases
CGCCCGGCCGGTGCCGATGGCGCCGCCGGCAAGTGCATGTCGGGTCTCGCACATCGACACCCGGGGCGCCACGGCTGCGC
TTGAAGATGCTGCCGCGCCG

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: Dihydroneopterin Aldolase Protein

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKPIDPPFSDPLAALDLSRLPGRGWSVFVDALTVPVRIGIHPHEHGAPQPIVIDAHLGYGCEPREDGDWIDYDGYCTRVT
AFLSGKPHTRLLETLAAEIAEWSFREWPALGLLTLAVHKPKIRPGTQRVGVALEWTRADYLRRCGKVA

Sequences:

>Translated_148_residues
MKPIDPPFSDPLAALDLSRLPGRGWSVFVDALTVPVRIGIHPHEHGAPQPIVIDAHLGYGCEPREDGDWIDYDGYCTRVT
AFLSGKPHTRLLETLAAEIAEWSFREWPALGLLTLAVHKPKIRPGTQRVGVALEWTRADYLRRCGKVA
>Mature_148_residues
MKPIDPPFSDPLAALDLSRLPGRGWSVFVDALTVPVRIGIHPHEHGAPQPIVIDAHLGYGCEPREDGDWIDYDGYCTRVT
AFLSGKPHTRLLETLAAEIAEWSFREWPALGLLTLAVHKPKIRPGTQRVGVALEWTRADYLRRCGKVA

Specific function: Unknown

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 16457; Mature: 16457

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIDPPFSDPLAALDLSRLPGRGWSVFVDALTVPVRIGIHPHEHGAPQPIVIDAHLGYG
CCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCCC
CEPREDGDWIDYDGYCTRVTAFLSGKPHTRLLETLAAEIAEWSFREWPALGLLTLAVHKP
CCCCCCCCEECCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECC
KIRPGTQRVGVALEWTRADYLRRCGKVA
CCCCCCCCEEEEEEEHHHHHHHHCCCCC
>Mature Secondary Structure
MKPIDPPFSDPLAALDLSRLPGRGWSVFVDALTVPVRIGIHPHEHGAPQPIVIDAHLGYG
CCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCCC
CEPREDGDWIDYDGYCTRVTAFLSGKPHTRLLETLAAEIAEWSFREWPALGLLTLAVHKP
CCCCCCCCEECCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECC
KIRPGTQRVGVALEWTRADYLRRCGKVA
CCCCCCCCEEEEEEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA