Click here to switch to the map view.

The map label for this gene is 17545525

Identifier: 17545525

GI number: 17545525

Start: 854059

End: 854844

Strand: Direct

Name: 17545525

Synonym: RSc0806

Alternate gene names: NA

Gene position: 854059-854844 (Clockwise)

Preceding gene: 17545524

Following gene: 17545526

Centisome position: 22.98

GC content: 69.97

Gene sequence:

>786_bases
ATGTCGTTTGCCATACGCCCCGGCGCCGCCGCATCCGGCGGCCGGATCAGCGAGGCCGAGCGCGCCGTGCGCATCGACCT
GGCCGCCGCCTACCGGCTGGCCGCGCTCAACGGTTGGGATGACCTGATCTACACCCATCTGTCGGCCACCGTCCCCGGTG
AGCCGGAGCACTTCCTCATCAACGCCTTCGGCCTGGCCTTCGACGAGATCACCGCCTCCAGCCTCGTCAAGATCAACCGC
GCCGGCCAGCTGGTCGGCGACTGGCCTGATCCCGCCGCGTGCCCGTCCGTCAACGTCACCGGCTTCGCGCTGCATGCCGC
CGTGCATGCGGCGCGTCCGGACGCGCATTGCGTGATCCACCTGCACAATACGGCGGGCATCGCGGTCTCCGCCCAGCAGC
ACGGGCTGCTGCCGCTGTCGCAGCACGCGCTGCGCTTCCACCGTCGCCTCGCCTATCACGACTACGAGGGCCTGGCCTTC
ACGCAGGAAGAGGGCGCGCGGCTGACCGCCTCGCTGGGCGGCCACCGCGCCATGCTGCTGCGCAACCACGGCACGCTCAC
GGTCGGCCGCACCGTGGCCGAGGCCCATGTGCTGATGGCCACGCTCATCAAGGCCTGCGAGATCCAGATCCAAGCGCTGA
CGGCCGGCGCGGTCATCACGCCCGCACCACGTGTTGCCGACCGCGCCGCCGAGCAACTGGAGGACGGCGGCGCCATCGAG
GGCATGCTGGAGTGGCCGGCCCTGCTGCGCAAACTGGATAGAATGAACCGCTCGTATCGCGACTAA

Upstream 100 bases:

>100_bases
GCGCCGGCCGGTGCGTGATGCCCGGCAGGCAGGGCACGGTGCCGCGCCGGTCGCCCGGCCGTTCTAGAATGCTTCCTCCA
CTGCCGCTGGAGGCGCACCG

Downstream 100 bases:

>100_bases
CCCGGGACCACCATGCCGACATTCCACATCGAGATGTTCGAGGGCCGCAGCGCCGACCAGAAGCGCAAGCTGGTCGAGGA
GGTCACGCGCGTCACCTGCG

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSFAIRPGAAASGGRISEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLINAFGLAFDEITASSLVKINR
AGQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIHLHNTAGIAVSAQQHGLLPLSQHALRFHRRLAYHDYEGLAF
TQEEGARLTASLGGHRAMLLRNHGTLTVGRTVAEAHVLMATLIKACEIQIQALTAGAVITPAPRVADRAAEQLEDGGAIE
GMLEWPALLRKLDRMNRSYRD

Sequences:

>Translated_261_residues
MSFAIRPGAAASGGRISEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLINAFGLAFDEITASSLVKINR
AGQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIHLHNTAGIAVSAQQHGLLPLSQHALRFHRRLAYHDYEGLAF
TQEEGARLTASLGGHRAMLLRNHGTLTVGRTVAEAHVLMATLIKACEIQIQALTAGAVITPAPRVADRAAEQLEDGGAIE
GMLEWPALLRKLDRMNRSYRD
>Mature_260_residues
SFAIRPGAAASGGRISEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLINAFGLAFDEITASSLVKINRA
GQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIHLHNTAGIAVSAQQHGLLPLSQHALRFHRRLAYHDYEGLAFT
QEEGARLTASLGGHRAMLLRNHGTLTVGRTVAEAHVLMATLIKACEIQIQALTAGAVITPAPRVADRAAEQLEDGGAIEG
MLEWPALLRKLDRMNRSYRD

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826323, Length=199, Percent_Identity=47.2361809045226, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI29826319, Length=199, Percent_Identity=47.2361809045226, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI29826321, Length=199, Percent_Identity=47.2361809045226, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI29826325, Length=199, Percent_Identity=47.2361809045226, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI297307158, Length=205, Percent_Identity=41.9512195121951, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI9257192, Length=205, Percent_Identity=41.9512195121951, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI9257190, Length=205, Percent_Identity=41.9512195121951, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI297307160, Length=205, Percent_Identity=41.9512195121951, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI89276787, Length=205, Percent_Identity=41.9512195121951, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI9943848, Length=212, Percent_Identity=41.5094339622642, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI9951927, Length=212, Percent_Identity=41.5094339622642, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI62912453, Length=212, Percent_Identity=41.5094339622642, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115533216, Length=251, Percent_Identity=36.2549800796813, Blast_Score=155, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115533218, Length=251, Percent_Identity=36.2549800796813, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71989555, Length=253, Percent_Identity=34.3873517786561, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71989560, Length=253, Percent_Identity=34.3873517786561, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71989544, Length=253, Percent_Identity=34.3873517786561, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71989550, Length=253, Percent_Identity=34.3873517786561, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71989541, Length=257, Percent_Identity=33.852140077821, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281363755, Length=205, Percent_Identity=37.5609756097561, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281363751, Length=205, Percent_Identity=37.5609756097561, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655690, Length=205, Percent_Identity=37.5609756097561, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655685, Length=205, Percent_Identity=37.5609756097561, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363761, Length=201, Percent_Identity=37.8109452736318, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363759, Length=201, Percent_Identity=37.8109452736318, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363753, Length=201, Percent_Identity=37.8109452736318, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI281363763, Length=201, Percent_Identity=37.8109452736318, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281363757, Length=201, Percent_Identity=37.8109452736318, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17136738, Length=201, Percent_Identity=37.8109452736318, Blast_Score=128, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 28004; Mature: 27873

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFAIRPGAAASGGRISEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLI
CCEECCCCCCCCCCCCHHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEE
NAFGLAFDEITASSLVKINRAGQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIH
EEHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
LHNTAGIAVSAQQHGLLPLSQHALRFHRRLAYHDYEGLAFTQEEGARLTASLGGHRAMLL
EECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCEEEEE
RNHGTLTVGRTVAEAHVLMATLIKACEIQIQALTAGAVITPAPRVADRAAEQLEDGGAIE
ECCCCEEECHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCC
GMLEWPALLRKLDRMNRSYRD
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFAIRPGAAASGGRISEAERAVRIDLAAAYRLAALNGWDDLIYTHLSATVPGEPEHFLI
CEECCCCCCCCCCCCHHHHHHEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEE
NAFGLAFDEITASSLVKINRAGQLVGDWPDPAACPSVNVTGFALHAAVHAARPDAHCVIH
EEHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
LHNTAGIAVSAQQHGLLPLSQHALRFHRRLAYHDYEGLAFTQEEGARLTASLGGHRAMLL
EECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCEEEEE
RNHGTLTVGRTVAEAHVLMATLIKACEIQIQALTAGAVITPAPRVADRAAEQLEDGGAIE
ECCCCEEECHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCC
GMLEWPALLRKLDRMNRSYRD
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]