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The map label for this gene is kynB [H]

Identifier: 17545479

GI number: 17545479

Start: 803960

End: 804589

Strand: Reverse

Name: kynB [H]

Synonym: RSc0760

Alternate gene names: 17545479

Gene position: 804589-803960 (Counterclockwise)

Preceding gene: 17545482

Following gene: 17545478

Centisome position: 21.65

GC content: 71.9

Gene sequence:

>630_bases
TTGGAACGTACTTTGTGGGACATCAGCCCCGCCCTCTCGACCGCCACGCCCACCTGGCCCGGCGACACGCCGTTTTCGCA
GGAAATTGCGTGGAAGCTGGAAGGCGACTGCCCGGTCAACGTCGGGCGCATCACGCTGTCGCCGCACACCGGTGCGCACG
CCGACGCGCCGCTGCACTACCACGCGGACGGCGCCCCGATCGGCGCGGTGCCGCTGGACGCCTATCTCGGCCCATGCCGC
GTCATCCACTGCGTGGGCGTGGCGCGCGTCGAGCCGGAGCACGTGCGCGATGCGCTGGACGGCGCGCCGCCGCGCGTGCT
GCTGCGCACCTATGCGCGCATGCCCCAGAACGCCTGGGATGACCACTTCGCCGCCGTCGCGCCCGAGACCATCGGACTGC
TGGCCGCGCACGGCGTGCGCCTGATCGGCACCGACACCGCCTCGCTCGATCCTCAGACCTCCAAGACCATGGACGCGCAT
CACGCCGTCGGCCGCCACGGCCTGGCCATCCTCGAGGGCCTGGTGCTCGACGACGTGCCCGCCGGCGACTACGAACTGAT
CGCCCTGCCGCTCAAGTTCGCCACGCTCGACGCCAGCCCGGTGCGCGCCGTACTGCGCCGCCTGCCCTGA

Upstream 100 bases:

>100_bases
ATCGCACGCACGAATATGCAAACCCATTTCGCACGGTTTTCCCTATCATTCCGGCACGGACGCCCGCTTTCCGACCCGCG
TTCTTGCCACCGGAGCCGCC

Downstream 100 bases:

>100_bases
CCGGCTCCACCGCTTTCACTGCCCCACAGTCGCCATGCCCCTCACCCGCAACACCTGCCTCGAACGCGACGCGGCCGACC
CGATCGCTCCGCTGCGCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MERTLWDISPALSTATPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYHADGAPIGAVPLDAYLGPCR
VIHCVGVARVEPEHVRDALDGAPPRVLLRTYARMPQNAWDDHFAAVAPETIGLLAAHGVRLIGTDTASLDPQTSKTMDAH
HAVGRHGLAILEGLVLDDVPAGDYELIALPLKFATLDASPVRAVLRRLP

Sequences:

>Translated_209_residues
MERTLWDISPALSTATPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYHADGAPIGAVPLDAYLGPCR
VIHCVGVARVEPEHVRDALDGAPPRVLLRTYARMPQNAWDDHFAAVAPETIGLLAAHGVRLIGTDTASLDPQTSKTMDAH
HAVGRHGLAILEGLVLDDVPAGDYELIALPLKFATLDASPVRAVLRRLP
>Mature_209_residues
MERTLWDISPALSTATPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYHADGAPIGAVPLDAYLGPCR
VIHCVGVARVEPEHVRDALDGAPPRVLLRTYARMPQNAWDDHFAAVAPETIGLLAAHGVRLIGTDTASLDPQTSKTMDAH
HAVGRHGLAILEGLVLDDVPAGDYELIALPLKFATLDASPVRAVLRRLP

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 22348; Mature: 22348

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTLWDISPALSTATPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHY
CCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEECEEEECCCCCCCCCCCEEE
HADGAPIGAVPLDAYLGPCRVIHCVGVARVEPEHVRDALDGAPPRVLLRTYARMPQNAWD
CCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
DHFAAVAPETIGLLAAHGVRLIGTDTASLDPQTSKTMDAHHAVGRHGLAILEGLVLDDVP
CCHHHHCHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AGDYELIALPLKFATLDASPVRAVLRRLP
CCCEEEEEEEEEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MERTLWDISPALSTATPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHY
CCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEECEEEECCCCCCCCCCCEEE
HADGAPIGAVPLDAYLGPCRVIHCVGVARVEPEHVRDALDGAPPRVLLRTYARMPQNAWD
CCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
DHFAAVAPETIGLLAAHGVRLIGTDTASLDPQTSKTMDAHHAVGRHGLAILEGLVLDDVP
CCHHHHCHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AGDYELIALPLKFATLDASPVRAVLRRLP
CCCEEEEEEEEEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA