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The map label for this gene is 17545463

Identifier: 17545463

GI number: 17545463

Start: 790072

End: 790899

Strand: Reverse

Name: 17545463

Synonym: RSc0744

Alternate gene names: NA

Gene position: 790899-790072 (Counterclockwise)

Preceding gene: 17545466

Following gene: 17545459

Centisome position: 21.28

GC content: 67.63

Gene sequence:

>828_bases
GTGCGCCTGATCCCGCGCGGATGCTATCCTTGCCCGCTTTTCGTCCGGCAGACCGAATTGGAAGGCAAGAACATGAAGCC
GCTGCGCTTCGCAAGGATCATTCGCGCAGCGCTGGCGGCCTGCGCGCTCGCAGCCGCACCCGCCATTGCCGCGACCACCG
GCTTTGAGCGGTGCCCGCAGTTTTTCGTGCACGGCCAGGTGCCGAAGGTCCACCGATTGGAGAGCGTCCGGCCGCGCGCG
CTGTGCTTCTCCTCGTTCGCGGTGATGTACTCGGGGCTCACCATGACGCCCCTCTACGTGGCCGAACGTCTGAACGCGGC
CCAGGTCGCGCGTGCCCGGGAGGAGCGCCGCACCAACCGCTTCTTCGCCGACGCCCGGCTGCCCAGCGTCGAGCGCGCCG
AGCTGGCCGACTACAGGGGCTCCGGTTTCGACCGCGGCCACATGGCCCCCGCGGGCGACATGCCGAACGACACCAGCATG
GCGCAAAGCTTCTCGCTGTCCAACATGGTGCCCCAGGCGCCCGAGAACAACCGCAAGGCGTGGGCTGGCATCGAAAAGGC
CACGCGCAAGTACGTCCTGCGCGCGCACGGCGACGTGTACGTCATCACCGGCCCGGTGTTCGTCCCGCCCTCGTCGACCA
TCGGCCCCCATCGGGTATGGGTACCGCACTACCTGTACAAGCTCGTCTACGATGCGACCACCCATCGCGCGTGGGCGCAC
TGGATTCAGAACACAGACACGGCGCGGGTGAGCCGACCGATTTCCTACCGCGAGCTGGTCAAGCGGACGGGGGTCGATTT
CTTGCCCGGGGTGCCGGTCGCCAACTGA

Upstream 100 bases:

>100_bases
TGCGGACGGAAGACATCGGGACCGGCGAGATAGAGGCGCAGGGACATGGACGTAGGCGCAATGAAAACATGGCCGCACAG
GATAACGCCCGGCCCGCGCC

Downstream 100 bases:

>100_bases
AACCGGCCACCTCGATCGGCCCGGCCCCGCTCCAGGTCCGGGCCTGCGATGCCTTCGTCATGCGGGCGGCTTCGATGCCA
ATCGGCGCACTTCAGATCGC

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRLIPRGCYPCPLFVRQTELEGKNMKPLRFARIIRAALAACALAAAPAIAATTGFERCPQFFVHGQVPKVHRLESVRPRA
LCFSSFAVMYSGLTMTPLYVAERLNAAQVARAREERRTNRFFADARLPSVERAELADYRGSGFDRGHMAPAGDMPNDTSM
AQSFSLSNMVPQAPENNRKAWAGIEKATRKYVLRAHGDVYVITGPVFVPPSSTIGPHRVWVPHYLYKLVYDATTHRAWAH
WIQNTDTARVSRPISYRELVKRTGVDFLPGVPVAN

Sequences:

>Translated_275_residues
MRLIPRGCYPCPLFVRQTELEGKNMKPLRFARIIRAALAACALAAAPAIAATTGFERCPQFFVHGQVPKVHRLESVRPRA
LCFSSFAVMYSGLTMTPLYVAERLNAAQVARAREERRTNRFFADARLPSVERAELADYRGSGFDRGHMAPAGDMPNDTSM
AQSFSLSNMVPQAPENNRKAWAGIEKATRKYVLRAHGDVYVITGPVFVPPSSTIGPHRVWVPHYLYKLVYDATTHRAWAH
WIQNTDTARVSRPISYRELVKRTGVDFLPGVPVAN
>Mature_275_residues
MRLIPRGCYPCPLFVRQTELEGKNMKPLRFARIIRAALAACALAAAPAIAATTGFERCPQFFVHGQVPKVHRLESVRPRA
LCFSSFAVMYSGLTMTPLYVAERLNAAQVARAREERRTNRFFADARLPSVERAELADYRGSGFDRGHMAPAGDMPNDTSM
AQSFSLSNMVPQAPENNRKAWAGIEKATRKYVLRAHGDVYVITGPVFVPPSSTIGPHRVWVPHYLYKLVYDATTHRAWAH
WIQNTDTARVSRPISYRELVKRTGVDFLPGVPVAN

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=157, Percent_Identity=36.3057324840764, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI224451073, Length=162, Percent_Identity=33.9506172839506, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI224451075, Length=126, Percent_Identity=38.0952380952381, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17505967, Length=159, Percent_Identity=31.4465408805031, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322253, Length=183, Percent_Identity=30.6010928961749, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581065, Length=159, Percent_Identity=34.5911949685535, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20129899, Length=159, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: 3.1.30.-

Molecular weight: Translated: 30770; Mature: 30770

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIPRGCYPCPLFVRQTELEGKNMKPLRFARIIRAALAACALAAAPAIAATTGFERCPQ
CCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FFVHGQVPKVHRLESVRPRALCFSSFAVMYSGLTMTPLYVAERLNAAQVARAREERRTNR
HHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
FFADARLPSVERAELADYRGSGFDRGHMAPAGDMPNDTSMAQSFSLSNMVPQAPENNRKA
EEHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
WAGIEKATRKYVLRAHGDVYVITGPVFVPPSSTIGPHRVWVPHYLYKLVYDATTHRAWAH
HHHHHHHHHHHHHEECCCEEEEECCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
WIQNTDTARVSRPISYRELVKRTGVDFLPGVPVAN
HHCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRLIPRGCYPCPLFVRQTELEGKNMKPLRFARIIRAALAACALAAAPAIAATTGFERCPQ
CCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FFVHGQVPKVHRLESVRPRALCFSSFAVMYSGLTMTPLYVAERLNAAQVARAREERRTNR
HHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
FFADARLPSVERAELADYRGSGFDRGHMAPAGDMPNDTSMAQSFSLSNMVPQAPENNRKA
EEHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
WAGIEKATRKYVLRAHGDVYVITGPVFVPPSSTIGPHRVWVPHYLYKLVYDATTHRAWAH
HHHHHHHHHHHHHEECCCEEEEECCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
WIQNTDTARVSRPISYRELVKRTGVDFLPGVPVAN
HHCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]