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The map label for this gene is tolC [H]

Identifier: 17545414

GI number: 17545414

Start: 743805

End: 745259

Strand: Reverse

Name: tolC [H]

Synonym: RSc0695

Alternate gene names: 17545414

Gene position: 745259-743805 (Counterclockwise)

Preceding gene: 17545415

Following gene: 17545400

Centisome position: 20.05

GC content: 69.55

Gene sequence:

>1455_bases
ATGACTGTTGCTCGCAGTAGCCGTGCGCGGATGGCCGCGCGCGGTTCGCTTATTGTGTTGTGCTGGTCGATGGCGCCGAT
GCTGGCCTGGGCCCAGGCCGATGCGCCGACGACCGACCTGCTGTCGGCCTACCGCGCCGCGCTCGCCAATGATCCGCAAT
TTGCTGCCGCGCGCGCGCAATCCGTCGCGCAGCACGAGAAGCTGACGCAGGGCCGCTCCGGCCTGCTGCCGCAGATCGGC
GCCGCCTGGAGTTCGACGCGCATCATCTTCGATCAGACCGCGCCTGCCGAATTCAACAAGACCTTCTCGTCGACAGGCTG
GACGCTATCGCTGTCGCAGCCGCTGTTCCGCTGGGACCGCTGGGAAACCTACAAGCAGGGCGAGATCGCCGCCGCCGCCT
CGGAAGCCAGCCTGGCGCAGGCGCAGCAGGACCTGATCACGCGCACGGCGCAGACTTACTTCGACGCGCTCAACGCCCAG
GACACGCTGCAGTTGGTCCTTGCGCAGCGCGATGCCATCCAGCAGCAGTACGAGCAGGCACGCCGCAACTTCGATGTCGG
CAACGCCAACATCACCGACGCCAACGATGCCCAGGCCCGGCGCGATGCGATCGACGCCACCGTCATCGCCGCCCGCAGCG
ACTTCGAGGTCAAGCAGTCCGCGCTCAGGCAGATCACCGGCGAGCCGGTCGGCAAGCTGGCGGGCGTGCGCACGGGGGTC
GCGTTGCCGCAGCCCGAGCCTGCTGCGCCGGAACGCTGGGTGGAACAGGCCCGCGGCAGCAACCCGCAGGTGGCGCTGGC
CCAGTACAACCTGCAGAACGCCGAGCACGACGTGAAGAAGGCCTCGGCCGGGCACCTGCCCTCCGTCGACCTGGTCGCGC
AGACCGGCCACACCAACGCCAGCGGCAACCAGTACCTGCCGTCCCTGCCGGGCGGCGCGCGCTTCGACAGCTCGCAGATC
GGCGTGCAGGTCTCGATTCCCCTCTATGCGGGCGGTGCGATCCAGTCACGCGTGCGCGAGAGCATCGCGCTGGAAACCGA
GGCCGCGAGCGACCTCGAGTACGCCCGCCGTACCGTCGAGCAGGGCGCGCGGCAAGCCTATATCGGCGTGATCGCGGGGC
TCGCGCAGGTGAAAGCGCTGGAAGCGGCCGAGGTATCGGCGCGCACGGCCTATGATTCGAACCAGCTCGCCTACGGCGTG
GGGGTGCGCATCGGCACCGACGTGCTCAACGCGCAGGCACAGCTGTTCTCGGCCCGGCGCGATCTGGCACGCGCGCGCTA
CGACACCATCGTCAATGGCCTGCGCCTGAAATCCGCCGCCGGCTCGCTGAGCGAGGCGGACATGGTGCAGGTCAACACGC
TGCTGACCGCCAACGCCTCGGAAGATCTGACCGCCCTGCCCCGGCCGGCGGCACGGGCCAAGCCCGCCGCCCCGGCCGCC
AACGCCAAGCGCTGA

Upstream 100 bases:

>100_bases
CCAGGTCGATCCGCAGATGGCGACGTACTGACAGGGGAAGCCGCGCGGGCGGCCCGCTCTGCCTGCGCTGCCTTCCGACG
TTTCCTCGTCCGGGGGCTTT

Downstream 100 bases:

>100_bases
CCCGCGCGTCAGTGCGGCTGCCCGCGCGGCGGCAGCGGGTGCTCGGCGAATTGCAGCAGTGCACCGCCGGCGGTCTTCCA
GATCACCTGGCGGCCCTGTG

Product: porin (omp) ABC transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTVARSSRARMAARGSLIVLCWSMAPMLAWAQADAPTTDLLSAYRAALANDPQFAAARAQSVAQHEKLTQGRSGLLPQIG
AAWSSTRIIFDQTAPAEFNKTFSSTGWTLSLSQPLFRWDRWETYKQGEIAAAASEASLAQAQQDLITRTAQTYFDALNAQ
DTLQLVLAQRDAIQQQYEQARRNFDVGNANITDANDAQARRDAIDATVIAARSDFEVKQSALRQITGEPVGKLAGVRTGV
ALPQPEPAAPERWVEQARGSNPQVALAQYNLQNAEHDVKKASAGHLPSVDLVAQTGHTNASGNQYLPSLPGGARFDSSQI
GVQVSIPLYAGGAIQSRVRESIALETEAASDLEYARRTVEQGARQAYIGVIAGLAQVKALEAAEVSARTAYDSNQLAYGV
GVRIGTDVLNAQAQLFSARRDLARARYDTIVNGLRLKSAAGSLSEADMVQVNTLLTANASEDLTALPRPAARAKPAAPAA
NAKR

Sequences:

>Translated_484_residues
MTVARSSRARMAARGSLIVLCWSMAPMLAWAQADAPTTDLLSAYRAALANDPQFAAARAQSVAQHEKLTQGRSGLLPQIG
AAWSSTRIIFDQTAPAEFNKTFSSTGWTLSLSQPLFRWDRWETYKQGEIAAAASEASLAQAQQDLITRTAQTYFDALNAQ
DTLQLVLAQRDAIQQQYEQARRNFDVGNANITDANDAQARRDAIDATVIAARSDFEVKQSALRQITGEPVGKLAGVRTGV
ALPQPEPAAPERWVEQARGSNPQVALAQYNLQNAEHDVKKASAGHLPSVDLVAQTGHTNASGNQYLPSLPGGARFDSSQI
GVQVSIPLYAGGAIQSRVRESIALETEAASDLEYARRTVEQGARQAYIGVIAGLAQVKALEAAEVSARTAYDSNQLAYGV
GVRIGTDVLNAQAQLFSARRDLARARYDTIVNGLRLKSAAGSLSEADMVQVNTLLTANASEDLTALPRPAARAKPAAPAA
NAKR
>Mature_483_residues
TVARSSRARMAARGSLIVLCWSMAPMLAWAQADAPTTDLLSAYRAALANDPQFAAARAQSVAQHEKLTQGRSGLLPQIGA
AWSSTRIIFDQTAPAEFNKTFSSTGWTLSLSQPLFRWDRWETYKQGEIAAAASEASLAQAQQDLITRTAQTYFDALNAQD
TLQLVLAQRDAIQQQYEQARRNFDVGNANITDANDAQARRDAIDATVIAARSDFEVKQSALRQITGEPVGKLAGVRTGVA
LPQPEPAAPERWVEQARGSNPQVALAQYNLQNAEHDVKKASAGHLPSVDLVAQTGHTNASGNQYLPSLPGGARFDSSQIG
VQVSIPLYAGGAIQSRVRESIALETEAASDLEYARRTVEQGARQAYIGVIAGLAQVKALEAAEVSARTAYDSNQLAYGVG
VRIGTDVLNAQAQLFSARRDLARARYDTIVNGLRLKSAAGSLSEADMVQVNTLLTANASEDLTALPRPAARAKPAAPAAN
AKR

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=452, Percent_Identity=31.1946902654867, Blast_Score=206, Evalue=4e-54,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51765; Mature: 51634

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVARSSRARMAARGSLIVLCWSMAPMLAWAQADAPTTDLLSAYRAALANDPQFAAARAQ
CCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
SVAQHEKLTQGRSGLLPQIGAAWSSTRIIFDQTAPAEFNKTFSSTGWTLSLSQPLFRWDR
HHHHHHHHHCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCHHHHHHH
WETYKQGEIAAAASEASLAQAQQDLITRTAQTYFDALNAQDTLQLVLAQRDAIQQQYEQA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRNFDVGNANITDANDAQARRDAIDATVIAARSDFEVKQSALRQITGEPVGKLAGVRTGV
HHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
ALPQPEPAAPERWVEQARGSNPQVALAQYNLQNAEHDVKKASAGHLPSVDLVAQTGHTNA
CCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCCCC
SGNQYLPSLPGGARFDSSQIGVQVSIPLYAGGAIQSRVRESIALETEAASDLEYARRTVE
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGARQAYIGVIAGLAQVKALEAAEVSARTAYDSNQLAYGVGVRIGTDVLNAQAQLFSARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEECHHHHHHHHHHHHHHH
DLARARYDTIVNGLRLKSAAGSLSEADMVQVNTLLTANASEDLTALPRPAARAKPAAPAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
NAKR
CCCC
>Mature Secondary Structure 
TVARSSRARMAARGSLIVLCWSMAPMLAWAQADAPTTDLLSAYRAALANDPQFAAARAQ
CCCCCHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
SVAQHEKLTQGRSGLLPQIGAAWSSTRIIFDQTAPAEFNKTFSSTGWTLSLSQPLFRWDR
HHHHHHHHHCCCCCCCCHHCCCCCCCEEEEECCCCHHHHHHHCCCCCEEECCCHHHHHHH
WETYKQGEIAAAASEASLAQAQQDLITRTAQTYFDALNAQDTLQLVLAQRDAIQQQYEQA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RRNFDVGNANITDANDAQARRDAIDATVIAARSDFEVKQSALRQITGEPVGKLAGVRTGV
HHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
ALPQPEPAAPERWVEQARGSNPQVALAQYNLQNAEHDVKKASAGHLPSVDLVAQTGHTNA
CCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCEEEECCCCCC
SGNQYLPSLPGGARFDSSQIGVQVSIPLYAGGAIQSRVRESIALETEAASDLEYARRTVE
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGARQAYIGVIAGLAQVKALEAAEVSARTAYDSNQLAYGVGVRIGTDVLNAQAQLFSARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEECHHHHHHHHHHHHHHH
DLARARYDTIVNGLRLKSAAGSLSEADMVQVNTLLTANASEDLTALPRPAARAKPAAPAA
HHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
NAKR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]