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The map label for this gene is pilG [H]

Identifier: 17545387

GI number: 17545387

Start: 712924

End: 713463

Strand: Direct

Name: pilG [H]

Synonym: RSc0668

Alternate gene names: 17545387

Gene position: 712924-713463 (Clockwise)

Preceding gene: 17545386

Following gene: 17545388

Centisome position: 19.18

GC content: 63.89

Gene sequence:

>540_bases
GTGGCCGTCGGGCCCACGCTGCGTGGCGATTTGCCGCGTTCCATCCGGTCGGAATGTCGTGGCGACCCGTCCGTGGTCGC
GCAACGCGAGAACATGATGCAATCCGCGCGGGTGGAACAACTGACCAATTCCCAACCGCTGGCGAGTTCGCTTGCCGGCC
GTAAAGTGCTGGTGATCGACGATTCCAGTACCATCCGCCGTACCGCGCAGATTTTCCTGTCCAAGGTCGATTGCCAGGTC
GTGCTGGCCGAAGACGGGTTCGATGCGCTGGCCAAGCTGGGTGACTTCAAGCCGGACATCGTCTTTTGCGACATCCTGAT
GCCCAAGCTGGACGGTTACCTGACCTGCTCACTGATCAAGAAAAGCCCGAAGTTTCATGCCACGCCCGTGGTCATGCTGT
CGTCGCGCGACGGGGTGTTCGACCGCGCGCGCGGCAAGCTGGTCGGGGCGGTGGACCACCTTGCCAAGCCTTTCTCGCGG
GAAGCGCTGCTGGAGGCGGTCCAGGCGCATCTGCCGGCAGCCGCTGGCGCCGCGCAATGA

Upstream 100 bases:

>100_bases
CCATTGACGGCGAATAGGTGACTTGTCACACTTCGACCCATTCTGAGCTTCACAACTTCATAAGCGGGCCGGGGGGCGTA
GTTTTGAAGTCGTTGCCAGC

Downstream 100 bases:

>100_bases
CGGCACCTCTTTAGAAAGAAGGACTGTTTGTATGGCAATCAAAAAGATTCTGGTGGTTGATGACTCCCCCACCGAAGCAC
TGTTCCTGTCGGAAATCCTG

Product: twitching motility two-component response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MAVGPTLRGDLPRSIRSECRGDPSVVAQRENMMQSARVEQLTNSQPLASSLAGRKVLVIDDSSTIRRTAQIFLSKVDCQV
VLAEDGFDALAKLGDFKPDIVFCDILMPKLDGYLTCSLIKKSPKFHATPVVMLSSRDGVFDRARGKLVGAVDHLAKPFSR
EALLEAVQAHLPAAAGAAQ

Sequences:

>Translated_179_residues
MAVGPTLRGDLPRSIRSECRGDPSVVAQRENMMQSARVEQLTNSQPLASSLAGRKVLVIDDSSTIRRTAQIFLSKVDCQV
VLAEDGFDALAKLGDFKPDIVFCDILMPKLDGYLTCSLIKKSPKFHATPVVMLSSRDGVFDRARGKLVGAVDHLAKPFSR
EALLEAVQAHLPAAAGAAQ
>Mature_178_residues
AVGPTLRGDLPRSIRSECRGDPSVVAQRENMMQSARVEQLTNSQPLASSLAGRKVLVIDDSSTIRRTAQIFLSKVDCQVV
LAEDGFDALAKLGDFKPDIVFCDILMPKLDGYLTCSLIKKSPKFHATPVVMLSSRDGVFDRARGKLVGAVDHLAKPFSRE
ALLEAVQAHLPAAAGAAQ

Specific function: Is involved in pilus biosynthesis and twitching motility. May act as a single-domain response regulator whose function may be to receive a certain environmental signal(s) and then transduce that signal to the pilus assembly machinery via specific protein-

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787487, Length=111, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=33.6206896551724, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=34.453781512605, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19289; Mature: 19157

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGPTLRGDLPRSIRSECRGDPSVVAQRENMMQSARVEQLTNSQPLASSLAGRKVLVID
CCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEE
DSSTIRRTAQIFLSKVDCQVVLAEDGFDALAKLGDFKPDIVFCDILMPKLDGYLTCSLIK
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEEHH
KSPKFHATPVVMLSSRDGVFDRARGKLVGAVDHLAKPFSREALLEAVQAHLPAAAGAAQ
CCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AVGPTLRGDLPRSIRSECRGDPSVVAQRENMMQSARVEQLTNSQPLASSLAGRKVLVID
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEE
DSSTIRRTAQIFLSKVDCQVVLAEDGFDALAKLGDFKPDIVFCDILMPKLDGYLTCSLIK
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCEEEEEHHHHHCCCEEEEEEHH
KSPKFHATPVVMLSSRDGVFDRARGKLVGAVDHLAKPFSREALLEAVQAHLPAAAGAAQ
CCCCCCCCEEEEEECCCCCHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8104179; 10984043 [H]