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The map label for this gene is ilvE1 [H]

Identifier: 17545286

GI number: 17545286

Start: 611073

End: 612002

Strand: Reverse

Name: ilvE1 [H]

Synonym: RSc0567

Alternate gene names: 17545286

Gene position: 612002-611073 (Counterclockwise)

Preceding gene: 17545297

Following gene: 17545285

Centisome position: 16.47

GC content: 65.7

Gene sequence:

>930_bases
ATGACCAGCATGGCTGACCGCGACGGCAAGATCTGGAAAGACGGCAAGCTGATCGAATGGCGCGACGCGCAACTCCACGT
GCTCACCCACACCCTGCACTACGGCATGGGCGTGTTCGAGGGCGTGCGCGCGTACCAGACGCCGGCCGGCCCCGCCATCT
TCCGCCTGTCCGAGCACACGCGCCGGCTGTTCAATTCGGCCAAGATCTTCCAGATGCAGATTCCGTTCTCGGAACAGCAG
CTGATGGACGCGCAGCGCGAAGTCGTGCGTGCCAACGCGCTGGCGTCCTGCTACATCCGCCCGCTGGCGTGGCTCGGCTC
CGAGAAGATGGGCGTGTCCGCCCGCGGCAACACCGTCCACGTGGCGATCGCCGCCTGGCCTTGGGGCGCCTACCTGGGCG
AAGAAGGCATGCAGCGCGGCATCCGCGTCAAGACGTCGTCCTTCACGCGCCACCATGTGAACGTGTCGCTGGTGCGCGCC
AAGGCCAGCGGCTACTACATCAACTCGATCCTCGCCAACCAGGAAGCCACCGGCCTGGGCTACGATGAAGCCCTGCTGCT
CGACACCGAGGGCTATGTGAGCGAAGGCTCGGGCGAGAACGTCTTCATCGTCCGCAACGGCGTGATCTACACGCCCGACC
TGGCCTCGTGCCTGGACGGCATCACCCGCGACGCAATCATCACCATCGCGGGCGACCTCGGCATCGAGGTGCGCGAGAAG
CGCATCACCCGCGACGAGATGTACTGCGCGGACGAAGCCTTCTTCACCGGCACCGCGGCGGAAGTCACCCCGATCCGCGA
ACTGGATGACCGCGTGATCGGCGCGGGCTCGCGCGGCCCGATCACCACGCAGCTGCAGTCGACGTTCTTCGACATCGTCA
ACGGCAAGAGCACCATCGAAAAGTACAAGGCGTGGCTGACCCTGGCCTGA

Upstream 100 bases:

>100_bases
ACGGAAACCGCCGCCAAGATCGGCGTTGGCGTCCCCGCCCCCACCCCTTACAATTCCGCCTTTGTCGGCATTTGAGCCCG
GACACTCACAGGAGCCCTCC

Downstream 100 bases:

>100_bases
CCACGCCCGCTGACCCTCATCATCATGACCACGCAAACCGCACCCATCATCGAAATCGGCGCAGACGACCTGCCGCTGCA
CTGCCCCACCAGCAAGACGC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTSMADRDGKIWKDGKLIEWRDAQLHVLTHTLHYGMGVFEGVRAYQTPAGPAIFRLSEHTRRLFNSAKIFQMQIPFSEQQ
LMDAQREVVRANALASCYIRPLAWLGSEKMGVSARGNTVHVAIAAWPWGAYLGEEGMQRGIRVKTSSFTRHHVNVSLVRA
KASGYYINSILANQEATGLGYDEALLLDTEGYVSEGSGENVFIVRNGVIYTPDLASCLDGITRDAIITIAGDLGIEVREK
RITRDEMYCADEAFFTGTAAEVTPIRELDDRVIGAGSRGPITTQLQSTFFDIVNGKSTIEKYKAWLTLA

Sequences:

>Translated_309_residues
MTSMADRDGKIWKDGKLIEWRDAQLHVLTHTLHYGMGVFEGVRAYQTPAGPAIFRLSEHTRRLFNSAKIFQMQIPFSEQQ
LMDAQREVVRANALASCYIRPLAWLGSEKMGVSARGNTVHVAIAAWPWGAYLGEEGMQRGIRVKTSSFTRHHVNVSLVRA
KASGYYINSILANQEATGLGYDEALLLDTEGYVSEGSGENVFIVRNGVIYTPDLASCLDGITRDAIITIAGDLGIEVREK
RITRDEMYCADEAFFTGTAAEVTPIRELDDRVIGAGSRGPITTQLQSTFFDIVNGKSTIEKYKAWLTLA
>Mature_308_residues
TSMADRDGKIWKDGKLIEWRDAQLHVLTHTLHYGMGVFEGVRAYQTPAGPAIFRLSEHTRRLFNSAKIFQMQIPFSEQQL
MDAQREVVRANALASCYIRPLAWLGSEKMGVSARGNTVHVAIAAWPWGAYLGEEGMQRGIRVKTSSFTRHHVNVSLVRAK
ASGYYINSILANQEATGLGYDEALLLDTEGYVSEGSGENVFIVRNGVIYTPDLASCLDGITRDAIITIAGDLGIEVREKR
ITRDEMYCADEAFFTGTAAEVTPIRELDDRVIGAGSRGPITTQLQSTFFDIVNGKSTIEKYKAWLTLA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=298, Percent_Identity=47.6510067114094, Blast_Score=290, Evalue=9e-80,
Organism=Caenorhabditis elegans, GI17565728, Length=327, Percent_Identity=24.7706422018349, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322002, Length=263, Percent_Identity=26.9961977186312, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34245; Mature: 34114

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMADRDGKIWKDGKLIEWRDAQLHVLTHTLHYGMGVFEGVRAYQTPAGPAIFRLSEHT
CCCCCCCCCCEECCCCEEEECCCEEEEEHHHHHHCCHHHHHHHHHCCCCCCEEEEEHHHH
RRLFNSAKIFQMQIPFSEQQLMDAQREVVRANALASCYIRPLAWLGSEKMGVSARGNTVH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEE
VAIAAWPWGAYLGEEGMQRGIRVKTSSFTRHHVNVSLVRAKASGYYINSILANQEATGLG
EEEEECCCHHHHCHHHHHCCEEEEECCCEEEEEEEEEEEEECCCEEEEHHHCCCCCCCCC
YDEALLLDTEGYVSEGSGENVFIVRNGVIYTPDLASCLDGITRDAIITIAGDLGIEVREK
CCCEEEEECCCCEECCCCCEEEEEECCEEECCCHHHHHCCCCCCEEEEEECCCCCEEHHH
RITRDEMYCADEAFFTGTAAEVTPIRELDDRVIGAGSRGPITTQLQSTFFDIVNGKSTIE
HCCHHHHHCCCCCEECCCCCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHH
KYKAWLTLA
HHHHHEECC
>Mature Secondary Structure 
TSMADRDGKIWKDGKLIEWRDAQLHVLTHTLHYGMGVFEGVRAYQTPAGPAIFRLSEHT
CCCCCCCCCEECCCCEEEECCCEEEEEHHHHHHCCHHHHHHHHHCCCCCCEEEEEHHHH
RRLFNSAKIFQMQIPFSEQQLMDAQREVVRANALASCYIRPLAWLGSEKMGVSARGNTVH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEE
VAIAAWPWGAYLGEEGMQRGIRVKTSSFTRHHVNVSLVRAKASGYYINSILANQEATGLG
EEEEECCCHHHHCHHHHHCCEEEEECCCEEEEEEEEEEEEECCCEEEEHHHCCCCCCCCC
YDEALLLDTEGYVSEGSGENVFIVRNGVIYTPDLASCLDGITRDAIITIAGDLGIEVREK
CCCEEEEECCCCEECCCCCEEEEEECCEEECCCHHHHHCCCCCCEEEEEECCCCCEEHHH
RITRDEMYCADEAFFTGTAAEVTPIRELDDRVIGAGSRGPITTQLQSTFFDIVNGKSTIE
HCCHHHHHCCCCCEECCCCCCCCCHHHHCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHH
KYKAWLTLA
HHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]