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The map label for this gene is ptsK [H]

Identifier: 17545124

GI number: 17545124

Start: 433305

End: 434279

Strand: Reverse

Name: ptsK [H]

Synonym: RSc0405

Alternate gene names: 17545124

Gene position: 434279-433305 (Counterclockwise)

Preceding gene: 17545125

Following gene: 17545123

Centisome position: 11.69

GC content: 66.67

Gene sequence:

>975_bases
ATGGAACTGACCGGCGTCACCGCCCAATCGATCTTCGACGACAATGCCGCCGACCTGAAGCTGTCGTGGGTCGCCGGCCT
GGAAGGCGCGGACCGCGCATTCGACGTGGATTTCGCCAAGGAAGCGACCTCCGCAGCCGATCTGGTGGGGCACTTGAACC
TGATCCACCCGAACCGCATCCAGGTGCTCGGCAAGCCCGAGATCACCTACTACCAGCGCCTGTCCGAAGAAAACCGCAAG
CGCCAGATGGGCGAGCTGATCCTGCTCGAGCCGCCCTTCCTGGTGGTGGCCGATGGCGTCGATCCGCCGCCCGACCTGGA
ACTGCGCTGCACGCGATCGTCCACGCCACTGTTCACGTCGCCGATTTCCTCCGCGGCCGTGATCGACCACCTGCGGCTGT
ATCTGTCGCGCATCTCGGCGCCGCGCGTGACGATGCACGGGGTGTTCCTCGACATCCTCGGCATGGGCGTGCTGATCATG
GGCGACTCCGGTCTGGGCAAGAGCGAGCTCGGGCTGGAACTGATCTCGCGCGGCCACGGCCTGGTGGCCGACGACGCGGT
CGACTTCGTGCGCCTGGGGCCGGACTTCATCGAGGGCCGCTGCCCGCCGCTGCTGCAGAACCTGCTGGAAGTGCGCGGCC
TGGGCCTGCTCGACATCAAGACCATCTTCGGCGAGACCGCGGTACGCCGGAAGATGAAGATCAAGCTGATCGTCCAGCTC
GTGCGCCGCAACGACGGCGAATTCGAGCGGCTGCCGCTGGATTCGCAATACATGGATGTGCTCGGCCTGCCCATCCACAT
GGTGAAGATCCAGGTGGCGGCCGGCCGCAACCTGGCCGTGCTGGTCGAGGCCGCCGTGCGCAACACCATCCTGCGGCTGC
GCGGCATCGACACGCTGCGCGACTTCATGGACCGCCAGCGTGCTGCCATGCAAGCCGAAGCCGCGTCGCACTCGCCGCAG
GGCCGCCTGCTTTAG

Upstream 100 bases:

>100_bases
CACCAGCTACTCACCGACTGGCGCCCTTAGGCCAAAGGCAACACGCCGCGGATGCCGCGGCCCGACCGCCCTCCACCCGA
GCGCCACGGAACGCACCGAC

Downstream 100 bases:

>100_bases
CAAAGTCTTTACAAAGCGCGCGCTCCGACAGGCGAGCGCGGCGACTTTCTCAAACTTTTGTAGAAAAACGTCAACCCGGC
ACACGGCCATTCCGTTGTGG

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYMDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL

Sequences:

>Translated_324_residues
MELTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYMDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL
>Mature_324_residues
MELTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYMDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35685; Mature: 35685

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRI
CCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTS
EEECCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCCEEC
PISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYMDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQAEAASHSPQGRLL
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELTGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRI
CCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTS
EEECCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCCEEC
PISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYMDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQAEAASHSPQGRLL
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA