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The map label for this gene is coaD

Identifier: 17545109

GI number: 17545109

Start: 418896

End: 419402

Strand: Direct

Name: coaD

Synonym: RSc0390

Alternate gene names: 17545109

Gene position: 418896-419402 (Clockwise)

Preceding gene: 17545108

Following gene: 17545110

Centisome position: 11.27

GC content: 62.52

Gene sequence:

>507_bases
ATGGTGATCGCGGTTTATCCCGGCACATTCGATCCGTTCACGCGCGGCCACGAGGATCTCGTGCGGCGCGCATCCAACAT
CTTCGACGAGCTTGTCGTCGGGGTGGCGCAGAGCCCGAACAAGCGGCCCTTCTTTGCGCTCGAGGAGCGCATCCACATCG
CGCGGGAAGTGCTGGGCCACTACCCCAACGTGCGGGTGGAAGGCTTTTCCGGCCTGCTCAAGGATTTCGTGCGCAAGAAC
AACGCGCGGGTGATCGTGCGCGGGCTGCGTGCCGTGTCGGACTTCGAGTACGAATTCCAGATGGCCGGCATGAACCGCTA
CCTGCTGCCTGACGTGGAAACCATGTTCCTCACGCCGTCCGACCAATACCAGTTCATCTCCGGCACTTTCGTGCGGGAGA
TTGCCCAGCTGGGCGGCGATGTCAGCAAGTTCGTCTTTCCGTCGGTGGAGCGGTGGCTGGTCGAGAAGGTCGGCCGCCGG
CATGCCGAGTCCGACAAAACGGCTTAA

Upstream 100 bases:

>100_bases
TCGGGGTCTGCCGTGCACGACAATCGTGTCCGACCGCAGCAGGCGCGGCCAAGTACCTCGCCGCGCCACCGGATGCTTTT
TTCCCCTTGGTGGAGGAACC

Downstream 100 bases:

>100_bases
AATGGCCGCTTGGCGGGAACGCTTCCGCCGGTCATTTCAAGGAAGGCATCATGGCGCTCATGATTACCGATGAGTGCATC
AATTGCGACGTCTGCGAGCC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MVIAVYPGTFDPFTRGHEDLVRRASNIFDELVVGVAQSPNKRPFFALEERIHIAREVLGHYPNVRVEGFSGLLKDFVRKN
NARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAQLGGDVSKFVFPSVERWLVEKVGRR
HAESDKTA

Sequences:

>Translated_168_residues
MVIAVYPGTFDPFTRGHEDLVRRASNIFDELVVGVAQSPNKRPFFALEERIHIAREVLGHYPNVRVEGFSGLLKDFVRKN
NARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAQLGGDVSKFVFPSVERWLVEKVGRR
HAESDKTA
>Mature_168_residues
MVIAVYPGTFDPFTRGHEDLVRRASNIFDELVVGVAQSPNKRPFFALEERIHIAREVLGHYPNVRVEGFSGLLKDFVRKN
NARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAQLGGDVSKFVFPSVERWLVEKVGRR
HAESDKTA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=49.0322580645161, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_RALSO (Q8Y2E6)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518511.1
- ProteinModelPortal:   Q8Y2E6
- SMR:   Q8Y2E6
- GeneID:   1219193
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0390
- NMPDR:   fig|267608.1.peg.390
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   RSOL267608:RSC0390-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19228; Mature: 19228

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIAVYPGTFDPFTRGHEDLVRRASNIFDELVVGVAQSPNKRPFFALEERIHIAREVLGH
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
YPNVRVEGFSGLLKDFVRKNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPS
CCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCEEEECCC
DQYQFISGTFVREIAQLGGDVSKFVFPSVERWLVEKVGRRHAESDKTA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVIAVYPGTFDPFTRGHEDLVRRASNIFDELVVGVAQSPNKRPFFALEERIHIAREVLGH
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
YPNVRVEGFSGLLKDFVRKNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPS
CCCCEECHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCEEEECCC
DQYQFISGTFVREIAQLGGDVSKFVFPSVERWLVEKVGRRHAESDKTA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852