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The map label for this gene is comF [H]

Identifier: 17545078

GI number: 17545078

Start: 389266

End: 389988

Strand: Reverse

Name: comF [H]

Synonym: RSc0359

Alternate gene names: 17545078

Gene position: 389988-389266 (Counterclockwise)

Preceding gene: 17545087

Following gene: 17545077

Centisome position: 10.49

GC content: 72.2

Gene sequence:

>723_bases
ATGCCCGTCCCGCTCCTGCTGCACCGGCTCGCCGCCGGCCTCCGCCATCTGCTGCCCTGCGCCTGCGCGCTGTGCGGCGC
CGTCCAGCATGACCTCGTCTGCGCAGGCTGCATGGCGGACATGTCACCGCTGCTGGATCGGCGCCGCTGCCGCCAGTGCG
CCAGGCCGCTCGACCGGCGGCATCCCGCGCGGCATTGCCCGGCCTGCCTGGCCGGCGCGCCGGACTTCGACGCCACCGTC
GTCATCGCCGACTACGCCTGGCCACTGGATCACCTTGTCACCGGATTGAAATTCCGCGCGCAGCTGCCGCTGGCCGCATG
GCTGGCCGAACGACTCGCCGACGCGCTGCTCGCTGCGCCAGGTACGCTGCCCGAGTTGCTGCTGCCCGTGCCGCTCTCCA
TGCCGCGCTTGCGCACGCGCGGCTACAACCAGGCCTGGGAAGTGGCGCGACGGCTGGGCCCACAGCTCGGCATCGCCGCG
ATTCCGGACGGGCTGCGCCGGCTGCGCGACAGCCCCGCCCAGTCGACACTGGACCGCGACGAACGCCTCGCCAACCTCCA
GGGCGCATTCGATGTGCCGGATCCGGCGTGCATTACCGGCCGCCACATCGGCGTGGTCGACGATGTGATGACCACGGGCG
CCACGCTGAGCGAGATCGCCACGCAGCTCAAGCGCGCGGGCGCGGCGCGGGTAACCAATTGCGTCGCCTTGCGCACACCC
TAG

Upstream 100 bases:

>100_bases
GAGGCAATGTGCTGCGGCCGCTCAGTATACCGGCGGGCCATTTCGGGGCGCTGTCCGATGGCGCGGCGCGCGCCGATCGG
TTTCGATGGGGCTTTTTGCC

Downstream 100 bases:

>100_bases
CAATATGCCTCTGCGGCATTGTGTCGCGCCCCTTATGGCAAGGTGACAACCCTTGCCGATGCCGATAAGCTCGCCGCCGG
TATTGCCCGGTCTGCCATCA

Product: competence protein F-related protein

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MPVPLLLHRLAAGLRHLLPCACALCGAVQHDLVCAGCMADMSPLLDRRRCRQCARPLDRRHPARHCPACLAGAPDFDATV
VIADYAWPLDHLVTGLKFRAQLPLAAWLAERLADALLAAPGTLPELLLPVPLSMPRLRTRGYNQAWEVARRLGPQLGIAA
IPDGLRRLRDSPAQSTLDRDERLANLQGAFDVPDPACITGRHIGVVDDVMTTGATLSEIATQLKRAGAARVTNCVALRTP

Sequences:

>Translated_240_residues
MPVPLLLHRLAAGLRHLLPCACALCGAVQHDLVCAGCMADMSPLLDRRRCRQCARPLDRRHPARHCPACLAGAPDFDATV
VIADYAWPLDHLVTGLKFRAQLPLAAWLAERLADALLAAPGTLPELLLPVPLSMPRLRTRGYNQAWEVARRLGPQLGIAA
IPDGLRRLRDSPAQSTLDRDERLANLQGAFDVPDPACITGRHIGVVDDVMTTGATLSEIATQLKRAGAARVTNCVALRTP
>Mature_239_residues
PVPLLLHRLAAGLRHLLPCACALCGAVQHDLVCAGCMADMSPLLDRRRCRQCARPLDRRHPARHCPACLAGAPDFDATVV
IADYAWPLDHLVTGLKFRAQLPLAAWLAERLADALLAAPGTLPELLLPVPLSMPRLRTRGYNQAWEVARRLGPQLGIAAI
PDGLRRLRDSPAQSTLDRDERLANLQGAFDVPDPACITGRHIGVVDDVMTTGATLSEIATQLKRAGAARVTNCVALRTP

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=229, Percent_Identity=34.4978165938865, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 25923; Mature: 25791

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPLLLHRLAAGLRHLLPCACALCGAVQHDLVCAGCMADMSPLLDRRRCRQCARPLDRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPARHCPACLAGAPDFDATVVIADYAWPLDHLVTGLKFRAQLPLAAWLAERLADALLAAP
CCHHHCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GTLPELLLPVPLSMPRLRTRGYNQAWEVARRLGPQLGIAAIPDGLRRLRDSPAQSTLDRD
CCHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHCCHHHHHHHHH
ERLANLQGAFDVPDPACITGRHIGVVDDVMTTGATLSEIATQLKRAGAARVTNCVALRTP
HHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHEEEECCC
>Mature Secondary Structure 
PVPLLLHRLAAGLRHLLPCACALCGAVQHDLVCAGCMADMSPLLDRRRCRQCARPLDRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPARHCPACLAGAPDFDATVVIADYAWPLDHLVTGLKFRAQLPLAAWLAERLADALLAAP
CCHHHCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GTLPELLLPVPLSMPRLRTRGYNQAWEVARRLGPQLGIAAIPDGLRRLRDSPAQSTLDRD
CCHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHCCCCCHHHCCHHHHHHHCCHHHHHHHHH
ERLANLQGAFDVPDPACITGRHIGVVDDVMTTGATLSEIATQLKRAGAARVTNCVALRTP
HHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]