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The map label for this gene is pcaD2 [H]

Identifier: 17545017

GI number: 17545017

Start: 330813

End: 331652

Strand: Reverse

Name: pcaD2 [H]

Synonym: RSc0298

Alternate gene names: 17545017

Gene position: 331652-330813 (Counterclockwise)

Preceding gene: 17545018

Following gene: 17545016

Centisome position: 8.92

GC content: 71.67

Gene sequence:

>840_bases
ATGACCGCAGACGCCATCACCGAATCGGGCCACGCCGATGCCAACGGCATCCGCATCCGCTACCGCATCGACGGCGCGGA
CGGGCCGTGGATCATGCTCGCGCACGCGCTCGGCGTGGACCACCAGATGTGGGACAGCATCGCGCACCGCCTCGCGTCGC
GCCACCGGGTCCTGCGCTACGACGCGCGCGGCCATGGCGGCACGACGGCGCCGCACGGCACGTACACGCTGTTCCAGATG
GCCGACGACGCGGCCGGCCTGCTCGATGCGCTGTCGATCCCGCAGGTCCATTTCGTCGGGCTGTCGATGGGCGGCATGGT
GGCGCAGATCCTGGGCGTGCGGCACCCGCAGCGGCTGCTGTCGCTGACCCTGTGCGACACGGTCTGCCATACGCCCGTTG
CCGCGCACGCCATGTGGGATGACCGCATCGGCCAGGTCGAGGCGCACGGCATGGCCGGCATCGTCGAGCCGACCCTGCAG
CGCTGGCTGACCACGCCGTTCCGCGAAGCGCATCCCGAGGTGGCCGCGCGCATCCGCGCGCTGCTGCTGGCCACCCCGCC
GCACGGCTATGTCGGCGCCTGCCTTGCCATCAAAGCGCTCGACACGCGCGATGCGCTGCCGCGCATTGCCTGCCCGGCCC
TCGTGGTGGTCGGCGAAGACGATGCGGGCGCGCCGCCCGACGTCGCGCGCGCGATCGCCGGCAGCCTGCCGAACGCGCGT
CTGAAAGTGATGCCGCATGCGGCCCACCTGGCCCCCATCGAACAGGAGGAGGCCTTCCTCACCGATCTGGACGAGTTCCT
CGGGCACGCGGGATGCGGCAGTCAGTGCGAGACGCCCTGA

Upstream 100 bases:

>100_bases
GCGGCTGGCTGCCGGTGCGCCTGCGCCAGACCGAACCCAGCGGCATGCAGTTCGAGCTCGTCTACCTGTCGCAGGACACC
GCCCCCAACGGAGCCACACC

Downstream 100 bases:

>100_bases
AGCGTCGCCGCACGCGATCGAGCTACAGGCGCCGCGCACACGGCGCGCTGTCCACCGGTCGGATGGAGGATGCGCGCTTG
CGTCTTTCGGGGCAGAGGCG

Product: B-ketoadipate enol-lactone hydrolase

Products: NA

Alternate protein names: 3-oxoadipate enol-lactonase I; Beta-ketoadipate enol-lactone hydrolase I; Enol-lactone hydrolase I [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTADAITESGHADANGIRIRYRIDGADGPWIMLAHALGVDHQMWDSIAHRLASRHRVLRYDARGHGGTTAPHGTYTLFQM
ADDAAGLLDALSIPQVHFVGLSMGGMVAQILGVRHPQRLLSLTLCDTVCHTPVAAHAMWDDRIGQVEAHGMAGIVEPTLQ
RWLTTPFREAHPEVAARIRALLLATPPHGYVGACLAIKALDTRDALPRIACPALVVVGEDDAGAPPDVARAIAGSLPNAR
LKVMPHAAHLAPIEQEEAFLTDLDEFLGHAGCGSQCETP

Sequences:

>Translated_279_residues
MTADAITESGHADANGIRIRYRIDGADGPWIMLAHALGVDHQMWDSIAHRLASRHRVLRYDARGHGGTTAPHGTYTLFQM
ADDAAGLLDALSIPQVHFVGLSMGGMVAQILGVRHPQRLLSLTLCDTVCHTPVAAHAMWDDRIGQVEAHGMAGIVEPTLQ
RWLTTPFREAHPEVAARIRALLLATPPHGYVGACLAIKALDTRDALPRIACPALVVVGEDDAGAPPDVARAIAGSLPNAR
LKVMPHAAHLAPIEQEEAFLTDLDEFLGHAGCGSQCETP
>Mature_278_residues
TADAITESGHADANGIRIRYRIDGADGPWIMLAHALGVDHQMWDSIAHRLASRHRVLRYDARGHGGTTAPHGTYTLFQMA
DDAAGLLDALSIPQVHFVGLSMGGMVAQILGVRHPQRLLSLTLCDTVCHTPVAAHAMWDDRIGQVEAHGMAGIVEPTLQR
WLTTPFREAHPEVAARIRALLLATPPHGYVGACLAIKALDTRDALPRIACPALVVVGEDDAGAPPDVARAIAGSLPNARL
KVMPHAAHLAPIEQEEAFLTDLDEFLGHAGCGSQCETP

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR012790 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.24 [H]

Molecular weight: Translated: 29819; Mature: 29688

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADAITESGHADANGIRIRYRIDGADGPWIMLAHALGVDHQMWDSIAHRLASRHRVLRY
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCEEEE
DARGHGGTTAPHGTYTLFQMADDAAGLLDALSIPQVHFVGLSMGGMVAQILGVRHPQRLL
ECCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCHHHHH
SLTLCDTVCHTPVAAHAMWDDRIGQVEAHGMAGIVEPTLQRWLTTPFREAHPEVAARIRA
HHHHHHHHHCCCHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHH
LLLATPPHGYVGACLAIKALDTRDALPRIACPALVVVGEDDAGAPPDVARAIAGSLPNAR
HHEECCCCCHHHHHHHEEECCCHHCCCHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCCE
LKVMPHAAHLAPIEQEEAFLTDLDEFLGHAGCGSQCETP
EEEECCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TADAITESGHADANGIRIRYRIDGADGPWIMLAHALGVDHQMWDSIAHRLASRHRVLRY
CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHCCEEEE
DARGHGGTTAPHGTYTLFQMADDAAGLLDALSIPQVHFVGLSMGGMVAQILGVRHPQRLL
ECCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCHHHHH
SLTLCDTVCHTPVAAHAMWDDRIGQVEAHGMAGIVEPTLQRWLTTPFREAHPEVAARIRA
HHHHHHHHHCCCHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHH
LLLATPPHGYVGACLAIKALDTRDALPRIACPALVVVGEDDAGAPPDVARAIAGSLPNAR
HHEECCCCCHHHHHHHEEECCCHHCCCHHCCCEEEEECCCCCCCCHHHHHHHHCCCCCCE
LKVMPHAAHLAPIEQEEAFLTDLDEFLGHAGCGSQCETP
EEEECCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181753 [H]