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The map label for this gene is argS

Identifier: 17545006

GI number: 17545006

Start: 319124

End: 320926

Strand: Reverse

Name: argS

Synonym: RSc0287

Alternate gene names: 17545006

Gene position: 320926-319124 (Counterclockwise)

Preceding gene: 17545009

Following gene: 17545005

Centisome position: 8.64

GC content: 69.94

Gene sequence:

>1803_bases
ATGCTGCCCTCCCACAAACAGACGATCTCCCAACTGCTGTCCGACGCCGTCGGCACCCTGCTGCCGGAAGGCACGAACCG
ACCGGAAATCGTCCTGGAGCGCCCCAAGCAGGCCGCGCACGGCGACATCGCGTGCAACGTCGCGCTGCAGCTGGCCAAGC
CGCTGGGCACCAATCCGCGCGAACTCGCCAACCGCATCGCCGACGGCATCCGCGCCGATGCGCGCGGCCAGCGGCTCGTC
TCGGCGGTGGAAATCGCCGGCCCGGGCTTCATCAACCTGCGCCTGTCGCCCACCGCCCGCACCGATGTGCTCGCCGCCGT
GTTCGCCGAGGGCGACCGCTACGGTGCCGCCGACCTCCATGACGGCGCGCCGGTGCTGGTGGAGTTCGTCTCGGCCAACC
CGACCGGCCCGCTGCACGTCGGCCACGGCCGCCAGGCGGCGCTGGGCGATGCGCTGGCCGCCCTGCTGGAGTGGCAGGGC
CACAAGGTCCACCGCGAGTTCTACTACAACGACGCGGGCGTGCAGATCCACAACCTGGCCGTCTCGGTGCAGGCCCGTGC
GCGCGGCTTCAAGCCGGGCGACACCGGCTGGCCCGAGGCCGCCTACAACGGCGACTACATCGCCGACATCGCCGCCGACT
ACCTCGCCGGCAAGACCGTGCGCGCCTCCGACGGCGAGCCGGTGACCGGCGCGCGCGACGTGGAGAACATCGAGGCCATC
CGCCGGTTCGCCGTCACGTACCTGCGCAACGAGCAGGACATCGACCTGCAGGCCTTCGGGGTGAAGTTTGACCACTACTA
CCTCGAATCGTCGCTGTACGCCGACGGCAAGGTGCAGCAGACCGTCGATGCGCTGATCGCCGCCGGCAAGACCTATGAGC
AGGAGGGCGCGCTGTGGCTGCGCACCACCGACGACGGCGACGACAAGGACCGCGTGATGCGCAAGTCCGACGGCAGCTAC
ACCTACTTCGTGCCGGACGTGGCCTACCACACCACCAAGTGGGGGCGCGGCTTCACACAGGTCATCAACGTGCAGGGCAG
CGACCACCACGGCACCATCGCCCGTGTGCGCGCCGGCCTGCAGGGCCTGGATCTCGGCATCCCCAAGGGCTACCCCGACT
ACGTCCTGCACAAGATGGTGACGGTGATGAAGGACGGCGCCGAGGTGAAGATCTCCAAGCGCGCCGGCTCCTATGTGACC
GTGCGCGACCTGATCGAATGGAGCAACGGCGACGCCGAGTCCGAAGCCGGCGTCGACACCATCCGCGCCTGCGTCGAGTC
GGGCGCGCCGAACTGGCCCGGGCGCTTCACGCGTGGCCGCGATGCGGTGCGCTTCTTCCTGCTGTCGCGCAAGGCGGATA
CGGAATTCGTCTTTGACGTGGACCTGGCGCTCAAGCAGAGCGACGAGAACCCGGTGTACTACGTGCAATACGCCCACGCC
CGGATCTGCTCGGTGTTCGAGCAGTGGCATGCGCGCGAGGGCGGCGACGCGGCTTCGCTCGCCGGGGCCGACCTGGCCGC
CGTGGCGGGCCCGGAAGCCAGCCCGCAGGCCGTCGCGCTGGTCCAGCGCATCGCCGCCTTCCCGGACATGCTGGCCGACG
CCGCCCGCGAACTGGCGCCGCACGCCGTCGCCTTCTACCTGCGCGACCTGGCGGGCGACTTCCACGCCTTCTACAACGCC
GACCGCGTGCTGGTGGACGATGACGCCGTCAAGCGTGCCCGCCTGGCGCTGCTGGCGGCCACGCGCCAGGTGCTGCGCAA
CGGCCTGGCGGTGATCGGTGTCTCGGCACCGCAAAAGATGTGA

Upstream 100 bases:

>100_bases
TCACCTGATAAAATTTCGTACTTTTCCCCGAACAACGCAACTGGTCGCGCCGGAACTGGATTTCAAACGGTTCCGACACG
GCCGGCGTCATGGCTTTCCT

Downstream 100 bases:

>100_bases
GGCGCACGACTGCCCGCCACACGGCGCTCTTATAATCGTCGGCGCATCTAGAAGGATCGACATGGCACGCAATACGCAAT
CTTCCCGTGCCCGCTCGCAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MLPSHKQTISQLLSDAVGTLLPEGTNRPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELANRIADGIRADARGQRLV
SAVEIAGPGFINLRLSPTARTDVLAAVFAEGDRYGAADLHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALAALLEWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGFKPGDTGWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGARDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYADGKVQQTVDALIAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGSY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLDLGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVESGAPNWPGRFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFEQWHAREGGDAASLAGADLAAVAGPEASPQAVALVQRIAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNA
DRVLVDDDAVKRARLALLAATRQVLRNGLAVIGVSAPQKM

Sequences:

>Translated_600_residues
MLPSHKQTISQLLSDAVGTLLPEGTNRPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELANRIADGIRADARGQRLV
SAVEIAGPGFINLRLSPTARTDVLAAVFAEGDRYGAADLHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALAALLEWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGFKPGDTGWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGARDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYADGKVQQTVDALIAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGSY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLDLGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVESGAPNWPGRFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFEQWHAREGGDAASLAGADLAAVAGPEASPQAVALVQRIAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNA
DRVLVDDDAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
>Mature_600_residues
MLPSHKQTISQLLSDAVGTLLPEGTNRPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELANRIADGIRADARGQRLV
SAVEIAGPGFINLRLSPTARTDVLAAVFAEGDRYGAADLHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALAALLEWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGFKPGDTGWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGARDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYADGKVQQTVDALIAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGSY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLDLGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVESGAPNWPGRFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFEQWHAREGGDAASLAGADLAAVAGPEASPQAVALVQRIAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNA
DRVLVDDDAVKRARLALLAATRQVLRNGLAVIGVSAPQKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=630, Percent_Identity=23.3333333333333, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1788184, Length=588, Percent_Identity=28.5714285714286, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI18859963, Length=637, Percent_Identity=23.7048665620094, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RALSO (Q8Y2P8)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518408.1
- ProteinModelPortal:   Q8Y2P8
- GeneID:   1219090
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0287
- NMPDR:   fig|267608.1.peg.287
- HOGENOM:   HBG695395
- OMA:   ETIRGCL
- ProtClustDB:   PRK01611
- BioCyc:   RSOL267608:RSC0287-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65086; Mature: 65086

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSHKQTISQLLSDAVGTLLPEGTNRPEIVLERPKQAAHGDIACNVALQLAKPLGTNPR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEHHHHHHHHCCCCCHH
ELANRIADGIRADARGQRLVSAVEIAGPGFINLRLSPTARTDVLAAVFAEGDRYGAADLH
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCC
DGAPVLVEFVSANPTGPLHVGHGRQAALGDALAALLEWQGHKVHREFYYNDAGVQIHNLA
CCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEHHEEECCCCCEEEEEE
VSVQARARGFKPGDTGWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGARDVENIEAI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHH
RRFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYADGKVQQTVDALIAAGKTYEQEGALWL
HHHHHHHHCCCCCCCEEEEEEEEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
RTTDDGDDKDRVMRKSDGSYTYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCCEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCC
QGLDLGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVTVRDLIEWSNGDAESEAGVDT
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHCCCCCCCCCCCHHH
IRACVESGAPNWPGRFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHH
RICSVFEQWHAREGGDAASLAGADLAAVAGPEASPQAVALVQRIAAFPDMLADAARELAP
HHHHHHHHHHCCCCCCHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HAVAFYLRDLAGDFHAFYNADRVLVDDDAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MLPSHKQTISQLLSDAVGTLLPEGTNRPEIVLERPKQAAHGDIACNVALQLAKPLGTNPR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEHHHHHHHHCCCCCHH
ELANRIADGIRADARGQRLVSAVEIAGPGFINLRLSPTARTDVLAAVFAEGDRYGAADLH
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCC
DGAPVLVEFVSANPTGPLHVGHGRQAALGDALAALLEWQGHKVHREFYYNDAGVQIHNLA
CCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEHHEEECCCCCEEEEEE
VSVQARARGFKPGDTGWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGARDVENIEAI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHH
RRFAVTYLRNEQDIDLQAFGVKFDHYYLESSLYADGKVQQTVDALIAAGKTYEQEGALWL
HHHHHHHHCCCCCCCEEEEEEEEEHEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
RTTDDGDDKDRVMRKSDGSYTYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCCEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCC
QGLDLGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVTVRDLIEWSNGDAESEAGVDT
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHCCCCCCCCCCCHHH
IRACVESGAPNWPGRFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHH
RICSVFEQWHAREGGDAASLAGADLAAVAGPEASPQAVALVQRIAAFPDMLADAARELAP
HHHHHHHHHHCCCCCCHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HAVAFYLRDLAGDFHAFYNADRVLVDDDAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852