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The map label for this gene is ucpA [C]

Identifier: 17545003

GI number: 17545003

Start: 316671

End: 317471

Strand: Reverse

Name: ucpA [C]

Synonym: RSc0284

Alternate gene names: 17545003

Gene position: 317471-316671 (Counterclockwise)

Preceding gene: 17545004

Following gene: 17545002

Centisome position: 8.54

GC content: 72.53

Gene sequence:

>801_bases
ATGAGTCAGATCGTCTTCATCACCGGCGCGTCGAGCGGCATCGGCCAGGCGCTGGCCCGCCAGTACGCCGCGCGCGGCGC
CACGCTCGGGCTGGTCGCGCGCCGCGTCGATGCCCTGCACGGCTTCGTGCAGACGCTGCCGGCGGGCATCGCTGTCCACT
GCTATGCCGCGGACGTGCGCGATGCCCGGTCGATGCACGACGCCGCCTCGGCATTCATGGCCGTGGCCGGCGTGCCCGAC
GTGGTGATCGCCAATGCCGGCATCTCGGTGGGCACCGACCTGCGCGAGGCCGGCGACCTGCCCGCCTTTGCCGCCGTGAT
GGAAACCAACTGGATGGGGGTGCTCCATACCCTGCAGCCCTTCGTCGGGCCCATGCTCGCGCGCGCCGAGCCCGGCCGGC
CGGGCGGGACGCTGGTGGGCATCGCCAGCGTGGCGGGCGTGCGGGGCCTACCGGGCGCGGCGGCCTACAGCGCGTCCAAG
GCGGCGGTGATCAAGCTGATGGAGAGCCTGCGCGTGGAGTTCAGCCCGAAGCGGCGACCGGGCCTGCGCGTGGTCACCCT
TGCGCCCGGCTACATCCGCACGCCGATGACCGAGCACAACCCCTATCCGATGCCCTTCCTGATGCCGGCGGACCGCTTTG
CCGAGCGGGCCGTGCAGGCCATCGACCGCGGCGCGCACTTCAAGGTGCTGCCGTGGCAGATGGGCGTGGTCGCCGGCCTG
CTCCACGTGCTGCCGCGCTGGCTGTACGACTTCGCCTTCGCGCACGCGCCGCGCAAGCCCCGCAACCCCGGAATCTCCTG
A

Upstream 100 bases:

>100_bases
GAGCCTGAGCCCCGGGCGCGACACCGTCGCCCACGCCCGCCTTCGCGCGGGCTTTTTTTGTGGTCGGCCACCCGGCCGCT
TCGTCGAAAAGGAATCCCGC

Downstream 100 bases:

>100_bases
TGACCTTCACCGACGCGCTCGGACAGGCGCACGCCCCCGTCGACACCACGCCGCGCATCGCCAGCCTGGTGCCGTCCATC
ACCGACCTGCTGTTCTCGCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSQIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPAGIAVHCYAADVRDARSMHDAASAFMAVAGVPD
VVIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQPFVGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASK
AAVIKLMESLRVEFSPKRRPGLRVVTLAPGYIRTPMTEHNPYPMPFLMPADRFAERAVQAIDRGAHFKVLPWQMGVVAGL
LHVLPRWLYDFAFAHAPRKPRNPGIS

Sequences:

>Translated_266_residues
MSQIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPAGIAVHCYAADVRDARSMHDAASAFMAVAGVPD
VVIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQPFVGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASK
AAVIKLMESLRVEFSPKRRPGLRVVTLAPGYIRTPMTEHNPYPMPFLMPADRFAERAVQAIDRGAHFKVLPWQMGVVAGL
LHVLPRWLYDFAFAHAPRKPRNPGIS
>Mature_265_residues
SQIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPAGIAVHCYAADVRDARSMHDAASAFMAVAGVPDV
VIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQPFVGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASKA
AVIKLMESLRVEFSPKRRPGLRVVTLAPGYIRTPMTEHNPYPMPFLMPADRFAERAVQAIDRGAHFKVLPWQMGVVAGLL
HVLPRWLYDFAFAHAPRKPRNPGIS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40807363, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=31.1881188118812, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI31543615, Length=234, Percent_Identity=27.3504273504274, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=28.7128712871287, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=253, Percent_Identity=25.296442687747, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=247, Percent_Identity=23.4817813765182, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=30.2439024390244, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=220, Percent_Identity=25.9090909090909, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4503817, Length=178, Percent_Identity=29.7752808988764, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=204, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=225, Percent_Identity=30.2222222222222, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508895, Length=250, Percent_Identity=26.8, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=245, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997402, Length=200, Percent_Identity=28, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=220, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI23397609, Length=200, Percent_Identity=35.5, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=277, Percent_Identity=29.9638989169675, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644339, Length=201, Percent_Identity=32.3383084577114, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=34.010152284264, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24643142, Length=221, Percent_Identity=28.9592760180996, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=30.7317073170732, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648693, Length=225, Percent_Identity=28.8888888888889, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355889, Length=225, Percent_Identity=28.8888888888889, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=28.75, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=217, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=29.2682926829268, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=197, Percent_Identity=31.4720812182741, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640442, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=221, Percent_Identity=29.8642533936652, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=29.5238095238095, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581726, Length=246, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28165; Mature: 28034

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPAGIAVHCYAADVR
CCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
DARSMHDAASAFMAVAGVPDVVIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQP
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHHCCHHHHHHHHHH
FVGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASKAAVIKLMESLRVEFSPKRRP
HHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLRVVTLAPGYIRTPMTEHNPYPMPFLMPADRFAERAVQAIDRGAHFKVLPWQMGVVAGL
CCEEEEECCCHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
LHVLPRWLYDFAFAHAPRKPRNPGIS
HHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SQIVFITGASSGIGQALARQYAARGATLGLVARRVDALHGFVQTLPAGIAVHCYAADVR
CEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
DARSMHDAASAFMAVAGVPDVVIANAGISVGTDLREAGDLPAFAAVMETNWMGVLHTLQP
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHHCCHHHHHHHHHH
FVGPMLARAEPGRPGGTLVGIASVAGVRGLPGAAAYSASKAAVIKLMESLRVEFSPKRRP
HHHHHHHCCCCCCCCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLRVVTLAPGYIRTPMTEHNPYPMPFLMPADRFAERAVQAIDRGAHFKVLPWQMGVVAGL
CCEEEEECCCHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
LHVLPRWLYDFAFAHAPRKPRNPGIS
HHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]