Click here to switch to the map view.

The map label for this gene is csgA [H]

Identifier: 17544994

GI number: 17544994

Start: 307080

End: 307790

Strand: Reverse

Name: csgA [H]

Synonym: RSc0275

Alternate gene names: 17544994

Gene position: 307790-307080 (Counterclockwise)

Preceding gene: 17544995

Following gene: 17544993

Centisome position: 8.28

GC content: 72.43

Gene sequence:

>711_bases
ATGACGAACGCGTCTTCCCGCTCCCGTACCGCCCTCGTCCTGGGCGCCTCGCGCGGCATCGGCCTGGAAACGGTCAGGCA
ATACCTGGCCGACGGCTGGCGCGTGATCGCCACCGTGCGCACCCAGGACGCCGCGCAGGCACTGCAGGCGCTGGGCGCCG
AGACCCACGTGCTGGACCTGACCGACGCCAACGCCATCGCCGGCCTGATCTGGAAGCTGGACGGCGAGGCGCTGGACGTG
GCGATCTACGTGGCGGGCATCTACGGCCCGCGCACGCAGCGCGCCGAGCCGGTCAGCCGCGCCGACTTCGACACCGTGAT
GCAGACCAACGTGTGGGGCCCGATGAGCGCGCTGCCGACGGTGCTGCCGATGGTCGAGGCCGGCCGCAACGGCGCGGGCG
AGCCGGGCGGCGTACTGGCCGTCGTCTCCAGCCGCATGGGCAGCATCGGCGGCATGGAAAGCAACGGCGGCTGGCTGTAT
CGCGCCAGCAAGGCGGCGGTCAATGCGGCGCTGCGCGCGCTGTCCTTCGATGCGCGCAACGCCATCTGCCTGACCTTCCA
TCCGGGCTGGGTGCGCACCGACATGGGCGGCGCCGGCGCGGCCATCACGCCGGCCGAGAGCGTGGCGGGCATGCGCCGCG
TGATCGCGGCCGCCACGCGCGGGGACAACGGCGCCTTCCGCAATTACGACGGCAGCGGCATCCAATGGTGA

Upstream 100 bases:

>100_bases
GCGCTGCGCCACCGCGGCGGCAAGCGCGGCGTGGCCAGCCTGTGCATCGGCGGCGGCGAGGCCACCGCGGTCGGCATCGA
ACTGCTGTGAGGCGCGCACG

Downstream 100 bases:

>100_bases
GGCCGGCACGATGCTCCTGACACCCGAACAAGAGATGATCCGCGACGCCATCCGCACCTTCGTGCGCGAGGCGATCGTGC
CGCACGCGGCCGCGTGGGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTNASSRSRTALVLGASRGIGLETVRQYLADGWRVIATVRTQDAAQALQALGAETHVLDLTDANAIAGLIWKLDGEALDV
AIYVAGIYGPRTQRAEPVSRADFDTVMQTNVWGPMSALPTVLPMVEAGRNGAGEPGGVLAVVSSRMGSIGGMESNGGWLY
RASKAAVNAALRALSFDARNAICLTFHPGWVRTDMGGAGAAITPAESVAGMRRVIAAATRGDNGAFRNYDGSGIQW

Sequences:

>Translated_236_residues
MTNASSRSRTALVLGASRGIGLETVRQYLADGWRVIATVRTQDAAQALQALGAETHVLDLTDANAIAGLIWKLDGEALDV
AIYVAGIYGPRTQRAEPVSRADFDTVMQTNVWGPMSALPTVLPMVEAGRNGAGEPGGVLAVVSSRMGSIGGMESNGGWLY
RASKAAVNAALRALSFDARNAICLTFHPGWVRTDMGGAGAAITPAESVAGMRRVIAAATRGDNGAFRNYDGSGIQW
>Mature_235_residues
TNASSRSRTALVLGASRGIGLETVRQYLADGWRVIATVRTQDAAQALQALGAETHVLDLTDANAIAGLIWKLDGEALDVA
IYVAGIYGPRTQRAEPVSRADFDTVMQTNVWGPMSALPTVLPMVEAGRNGAGEPGGVLAVVSSRMGSIGGMESNGGWLYR
ASKAAVNAALRALSFDARNAICLTFHPGWVRTDMGGAGAAITPAESVAGMRRVIAAATRGDNGAFRNYDGSGIQW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI193207563, Length=240, Percent_Identity=30.8333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558996, Length=252, Percent_Identity=28.968253968254, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558994, Length=248, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559962, Length=241, Percent_Identity=30.2904564315353, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532177, Length=241, Percent_Identity=28.6307053941909, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=242, Percent_Identity=30.9917355371901, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17558992, Length=245, Percent_Identity=30.2040816326531, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558990, Length=242, Percent_Identity=26.4462809917355, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322779, Length=259, Percent_Identity=28.957528957529, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640547, Length=244, Percent_Identity=31.9672131147541, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24633; Mature: 24502

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNASSRSRTALVLGASRGIGLETVRQYLADGWRVIATVRTQDAAQALQALGAETHVLDL
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECHHHHHHHHHCCCCCEEEEE
TDANAIAGLIWKLDGEALDVAIYVAGIYGPRTQRAEPVSRADFDTVMQTNVWGPMSALPT
CCCHHHEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
VLPMVEAGRNGAGEPGGVLAVVSSRMGSIGGMESNGGWLYRASKAAVNAALRALSFDARN
HHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCC
AICLTFHPGWVRTDMGGAGAAITPAESVAGMRRVIAAATRGDNGAFRNYDGSGIQW
EEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNASSRSRTALVLGASRGIGLETVRQYLADGWRVIATVRTQDAAQALQALGAETHVLDL
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEEEECHHHHHHHHHCCCCCEEEEE
TDANAIAGLIWKLDGEALDVAIYVAGIYGPRTQRAEPVSRADFDTVMQTNVWGPMSALPT
CCCHHHEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
VLPMVEAGRNGAGEPGGVLAVVSSRMGSIGGMESNGGWLYRASKAAVNAALRALSFDARN
HHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCC
AICLTFHPGWVRTDMGGAGAAITPAESVAGMRRVIAAATRGDNGAFRNYDGSGIQW
EEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]