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The map label for this gene is aidB [H]

Identifier: 17544840

GI number: 17544840

Start: 142057

End: 143730

Strand: Direct

Name: aidB [H]

Synonym: RSc0121

Alternate gene names: 17544840

Gene position: 142057-143730 (Clockwise)

Preceding gene: 17544839

Following gene: 17544841

Centisome position: 3.82

GC content: 71.8

Gene sequence:

>1674_bases
ATGCCCGCCGACGCCACCCATCGCGTCTTCAACCAGGTCCCCGATCTCGCGCATTTCAATCCGTTCACGTCGGACGCCAC
GCTGCAGGGCGCGCTCGGCCGGCTCGGTGGCGGCTGGCATGCCGATGCGCTGCGGGCGTTCGGCGAGACGCTGGGGTCCC
CCCGGACGCTGGCCTGGGCGGCCGAGGCCAACCGGTACCCGCCGGAGCTTCACACCCACAGCCGCACCGGCGAGCGCATC
GACAGCGTGCGCTTCGATCCGGCCTGGCATGCGCTGCTCGGGCTGATGCGCGGCCAGGGCCTGCAGGCGCTGCCGTTTGC
CGAGCCCCGCGCCGGCGCCTGGGCTGCGCGTACCGCCGGGTATTTCATGCAGGCGCAGATCGAGTCCGGCTCGCTGTGTC
CGGCCACCATGACCTTCGCCAGCATCCCCGTGCTGCAGAAGGAGACCGCGCTGTTCGCCGACCTGGCGCCGCGCCTCTAC
GCCCGCGAGCATGACGCGCGCGATCTGCCGTGGCGGCAGAAGACCGCCATCCTGGTCGGCATGGGCATGACGGAAAAGCA
GGGCGGTTCGGACGTGCGCAGCAACACCACCGTGGCGGTGCCCTTGGGTGGCAAGGACGGGGGCGAGGGGCGCGGCGCCA
CGTACGCGCTCACCGGGCACAAGTGGTTCTTCTCCGCGCCGATGTGCGATGCGCATCTTGTGGTGGCGCGCATGGGCGCG
GAGGATGGGCCGCTGTCGTGCTTCTTCGTGCCGCGCTGGCGCGACGACGGCGGCAAGAACCCGGTCCAGATCCAGCGGCT
CAAGGACAAGCTCGGCAACTGCTCCAACGCGAGCAGCGAGGTGGAGTTCCGCGCGGCGCAGGGCATCCTGATCGGCGAGG
CGGGGCGCGGCATCCCGACCATCCTCGAGATGGCGACGCACACGCGGCTCGACTGCGTGATCGGCAGCGCGGCCCTCCTG
CGCCACGCGCTGATGCAGGCGCTGCACCATGCGCGCCACCGCATGGCGTTCGGCCGCCTGCTGGCGGACCAGCCGCTGAT
GCGCAACGTGCTGGCCGACCTCGCGCTCGAATCGCAGGCCGCCACGCTGCTGATGATGGCGCTGGGCGATGCGTTCGAGC
GGGCCGAGGCCGATCCGGTCGCCGCCGCCTGGAAGCGCATCGTCACGCCGGCCGCCAAGTTCTGGGTCTGCAAGCGCGCC
ATCGAAGCCACTGGCGAGGCGATGGAAGTGTGGGGCGGCAACGGCTACGTGGAAGAGGGCCCGATGGCCCGCCTGTACCG
CGAGGCGCCGGTCAATTCCATCTGGGAAGGCTCGGGCAACGTGATGTGCCTGGACGTGCTGCGCGCCATCGGCCGCGTGC
CGGACGATGCGCTGCGGCTGGTGCAGGACATCGGCGAGCGCGCGCGGGGCCATCGCGCCGTGCGGGCCGAGCTGGCGGCG
CTGCAGGCCATGCTGCACCAATCCGGTGATATCCAGGAGGCCTCGGCGCGGCGCATCGCCCAGGGACTGGCGCTGACGGC
CCAGGCCGCGCTGATGCTCGCCCATGCGCACGCCGACGACGCCGAGCGCTTCATCGCCAGCCGCTTCCATCATCAGCACG
GCCGCGTGTTCGGCACGCTGGAGGGCAACGCGCAGGAACTGGGGGCGGCGCTGCAGCGCGCGTGGCCGGCCTGA

Upstream 100 bases:

>100_bases
GCGCGGCGGCTTGAGCGTCTGGAGTCCGCGCTGCGCTGCCGTGCGCGAGGGGTGGTCTACCATGGGGGTCGGCCATGACG
ATCTGCCCAGGAGACTTCCC

Downstream 100 bases:

>100_bases
TGCCCGGGTCCGGACGGTCAATAGTGGTACTGCGGCCACATGTCGCACTGATTGGCCGCCCATGGCGACGGCCTGCCCGG
CACCACGGCGTGCTCCATAT

Product: oxidoreductase flavoprotein FAD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MPADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWAAEANRYPPELHTHSRTGERI
DSVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAGYFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLY
AREHDARDLPWRQKTAILVGMGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGA
EDGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPTILEMATHTRLDCVIGSAALL
RHALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQAATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRA
IEATGEAMEVWGGNGYVEEGPMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAA
LQAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTLEGNAQELGAALQRAWPA

Sequences:

>Translated_557_residues
MPADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWAAEANRYPPELHTHSRTGERI
DSVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAGYFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLY
AREHDARDLPWRQKTAILVGMGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGA
EDGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPTILEMATHTRLDCVIGSAALL
RHALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQAATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRA
IEATGEAMEVWGGNGYVEEGPMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAA
LQAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTLEGNAQELGAALQRAWPA
>Mature_556_residues
PADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWAAEANRYPPELHTHSRTGERID
SVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAGYFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLYA
REHDARDLPWRQKTAILVGMGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGAE
DGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPTILEMATHTRLDCVIGSAALLR
HALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQAATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRAI
EATGEAMEVWGGNGYVEEGPMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAAL
QAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTLEGNAQELGAALQRAWPA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=271, Percent_Identity=25.830258302583, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4557231, Length=282, Percent_Identity=24.113475177305, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI187960098, Length=282, Percent_Identity=24.113475177305, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI4557235, Length=297, Percent_Identity=23.5690235690236, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI76496475, Length=297, Percent_Identity=23.5690235690236, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI87082384, Length=517, Percent_Identity=47.5822050290135, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI87081958, Length=267, Percent_Identity=24.3445692883895, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=565, Percent_Identity=28.4955752212389, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI86563381, Length=565, Percent_Identity=28.4955752212389, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=278, Percent_Identity=25.1798561151079, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=334, Percent_Identity=24.8502994011976, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=287, Percent_Identity=22.9965156794425, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17506239, Length=305, Percent_Identity=22.6229508196721, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355753, Length=422, Percent_Identity=23.2227488151659, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60298; Mature: 60167

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWA
CCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEE
AEANRYPPELHTHSRTGERIDSVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAG
CCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHC
YFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLYAREHDARDLPWRQKTAILVG
EEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
MGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGA
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHCCC
EDGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPT
CCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHCCEEEECCCCCHHH
ILEMATHTRLDCVIGSAALLRHALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRAIEATGEAMEVWGGNGYVEEG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
PMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAA
HHHHHHHHCCCCHHHCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
LQAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEE
EGNAQELGAALQRAWPA
CCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PADATHRVFNQVPDLAHFNPFTSDATLQGALGRLGGGWHADALRAFGETLGSPRTLAWA
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEE
AEANRYPPELHTHSRTGERIDSVRFDPAWHALLGLMRGQGLQALPFAEPRAGAWAARTAG
CCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHC
YFMQAQIESGSLCPATMTFASIPVLQKETALFADLAPRLYAREHDARDLPWRQKTAILVG
EEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
MGMTEKQGGSDVRSNTTVAVPLGGKDGGEGRGATYALTGHKWFFSAPMCDAHLVVARMGA
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHCCC
EDGPLSCFFVPRWRDDGGKNPVQIQRLKDKLGNCSNASSEVEFRAAQGILIGEAGRGIPT
CCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHCCEEEECCCCCHHH
ILEMATHTRLDCVIGSAALLRHALMQALHHARHRMAFGRLLADQPLMRNVLADLALESQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ATLLMMALGDAFERAEADPVAAAWKRIVTPAAKFWVCKRAIEATGEAMEVWGGNGYVEEG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
PMARLYREAPVNSIWEGSGNVMCLDVLRAIGRVPDDALRLVQDIGERARGHRAVRAELAA
HHHHHHHHCCCCHHHCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
LQAMLHQSGDIQEASARRIAQGLALTAQAALMLAHAHADDAERFIASRFHHQHGRVFGTL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEE
EGNAQELGAALQRAWPA
CCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]