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The map label for this gene is frpA [H]

Identifier: 17544823

GI number: 17544823

Start: 119027

End: 121909

Strand: Reverse

Name: frpA [H]

Synonym: RSc0104

Alternate gene names: 17544823

Gene position: 121909-119027 (Counterclockwise)

Preceding gene: 17544824

Following gene: 17544814

Centisome position: 3.28

GC content: 62.16

Gene sequence:

>2883_bases
ATGGCTCGTGCATATCTGGACACTTTGGAAAAAATCGCCGAGGAGAATCGAAAACTCACCGGCAATGACGAAGTCAATAG
GGACATTCAAGCCAAAGAGGTCTGGGATTTCCACAGGGAGGTTTTCCAAAAAAACGGCCTGGGTGTGGAAAACTGGACCC
TAGACTCCGTCTTCAAAACCATCCAGCAAACCCAAGGCGACGACGCCCTGGAAGCCTATTGGGAAAGCCTGCGCGATACC
CAAGGCGAAGGGATGATGGCCACGCTGTTGAACATCCGCACGATGTACAACATGCACGAAAGCATCGACAGCGCCGACCC
CGCCATCAGCAAACTCGCCAGAAACTGGATGGAGTTGGTACCCGGCATCTTCAGCTCCGAGCAGTTCATGCGCAGCATCA
AGGTGCTGCTCAGACTTCCCGACGTCAAATCCACACTGAACGCCATCGACGATCTGGTCAACCAGCTCTTCCGCAGCGTG
CAATTCGACAGCGGCCGCGACCCGCTCGTGGTCGATCTGGGCAAGGGCATCCGAGCCACCGGCGTCGATGACAGCAAGGT
CCTGTTCGATCTCGCCAACGCCGGCCAGAAGGAAGCGGTCGGATGGATCGCCTCCGGCGGCTTCCTCGTCAACACTGCGG
ATGGCCCCGTCACCAGCGGCGCCCAACTCTTCGGCGATGCCCGCGCATTGCCCGACGGATCGCTCGCCGCCAACGGCTTC
CAGGCGCTCGCCCCGCTGGACAGCAACGCCGACGGCCACATCAACGCCAGCGACACCGCCTTCGGCAAGCTCGCGATCTG
GACCGATACCAATCAGGACGGCATCGAGCAAGCCGACGAAGTGTTTCTGCTCAGCAAGCTCGGCATCCAGGACATCGACC
TGACCAGCGAGACCAGCACCTTCCAGAACATCGGCGGCGGCAACGTCGTCACCGGCAAGGCAAAGATCACCTGGGCCGAC
GGCCACCAGACCGACATCGTCGAAGCCAACCTCGTCACCAATGGCTTCTACACGGTCTTCACCGATAACGTGACGCTCAC
ACCAGAACAGGCCGCGCTGCCCTTTGTTCGCGGCAGCGGACAAGTCCGGGATACCCGGCAGGCTGCCGCACGCTCCCCAG
ATTTCTCGGCGATGCTGCAGCAGTACGCCGCCGCAAACACCCGTGCCGAGCAACTCGCGCTGCTGCCCGCGCTGATCGAC
GCATGGGCAGCCACCAGCTCGTTCAAGTCGCTCATGCAGCGCAACACCTACGCCAATGACAGCGTCAACTATGAATACGC
GTTCACAGGTGTTGCGCACTACCAGTCGACCACCCTGGGCTATGACGCGCTGATAGCCAAGAGCAACTGGACCGCCGAGT
ACAGCAAGTGGACCCATCTGGTCGACATCCTGGAGAAGTTCAACGGCCAGACGCTGTTTTCCGTCGATTCCGGCTGGATG
TGGGGCCATAACCGTGCCTTCGTGTCCGCCGTCAACACGGATGGATCGACCAGTGCTTATAACGGTGCCAGCCCGCAGGC
TGGTGCGCTGCTCCAAGCCACCGTGCTGCAGATATCCCTTTCCGACCAGCAGATGGCACGCCTGCAGCAAAGCTACGATG
CCCTGCTGGACTCTGTCTACGGCGGCCTGGTCCTGCAGACCCGCCTGGACAAATACGTCCGCATCCTCCAGTCCGACCAC
CCGGCAGATGTACTCGCTGCGCTACAAGCCGCGTATGACCGGAATCCAGTCAACGGCGCATCGGATGCGATCGACCTGCT
CAAGTATGGCAGCGCCGCGCTGGACAAGGCCGGCGTCTCCCTGGCGCCGACGCTCCAGTCCATGGCGCAAGACTTGGACA
GCCGGGGCCTGCTCTCGACCTGGCTCGCCGACAACCCGGGCATCCACTACACGGCCCCCGGCCAAGCCGCCGCTATCGGC
AAGACTGGCGAACTGAACGGCCTGTTCATTCTGACCGGTCCCACCCAGAAAGCCGACCCCGTCCAGGCCAGCGCGGGACA
GGGCAGCCAAGGCAACGTGTTCTTCGCGCTGCACGGCAACACCACCGTGGATGCCAGTAAGGGGGACAACCAGCAGTTCT
TCGGCGGCGATGGTCCAAGCCGGTTCGTTGGCGGCACCGGAGCCAACCGCTTCCAGGGCGGCGCCGGAGACATGTGGATG
GACGGCCACCTCGGCTCAGCCGGCACATTTACGGGCGGCAAGGGCAACGACACCATGATCGGTGGCACGGGGCTGAACAT
CTTCTCCGGCGGCGGCGGTGATGACGCCATCACGTCGAACGCCGACGCCGTCAGCCTCATCGATGGCGGGATAGGCAACG
ATACGATCCGGGTCAGCGGCGGCGGTATGGCCTCTATCGATGGTGGCGCTGGCGACGACATCATCAGAATCGATCCCTAC
GGCGCCTCTCAAGGTGCCGACATCATGGGCGGCACCGGCGACGACCAGATCAGCCTCGGCTACTACAGCACCACCCTACG
ATTCAACCGCGGTGATGGCCATGACACCGTTTCGTCCATCGCCAACGCCGGCAACAAGACCATCGTCTTCGGCCCCGGCA
TCAGCGCCGCCGACCTCTCCGCCACCCGCGTTGGCAACGACATGGTCCTGAACGTCGGCGCCAATGGTGACGCTATCACC
ATCACGAACTGGTTCTTGTTGGATGGCTCCAAGCGCATCGATACCGCCGTCTTCGCCGATGGCACCCGATGGAATGCCGA
CAACTTCCGCCGCCTCATCACCACCGTAACCGGTACCGCCGGTGACGACACCATCAACGGCTGGCAGGGCGATGACGTCC
TCGTCGGTGGCGACGGCAACGACACCCTAGTGTCCCGTTCCGCTAATTCGTTCGCAAAGTCTGCTGAGCTTGGAGAGGAT
TGA

Upstream 100 bases:

>100_bases
TTCTGCCATCGACTACCTGACTGGCTCTGCCTTGATGGGGATGGGAGGACAGGCTTGCTGGAACGTTTCCCCCGAAAGAG
CTGACTCGATCAAACAGGGG

Downstream 100 bases:

>100_bases
ATCAGCGGTCGCGGTCCAAGCGAATGGTTTGCAGTTCTGGTTGTAGTGAGCGACGAAGTGATCGATCTTCTGAACCAGTT
CCTTAACCGACGTGAACGAG

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 960; Mature: 959

Protein sequence:

>960_residues
MARAYLDTLEKIAEENRKLTGNDEVNRDIQAKEVWDFHREVFQKNGLGVENWTLDSVFKTIQQTQGDDALEAYWESLRDT
QGEGMMATLLNIRTMYNMHESIDSADPAISKLARNWMELVPGIFSSEQFMRSIKVLLRLPDVKSTLNAIDDLVNQLFRSV
QFDSGRDPLVVDLGKGIRATGVDDSKVLFDLANAGQKEAVGWIASGGFLVNTADGPVTSGAQLFGDARALPDGSLAANGF
QALAPLDSNADGHINASDTAFGKLAIWTDTNQDGIEQADEVFLLSKLGIQDIDLTSETSTFQNIGGGNVVTGKAKITWAD
GHQTDIVEANLVTNGFYTVFTDNVTLTPEQAALPFVRGSGQVRDTRQAAARSPDFSAMLQQYAAANTRAEQLALLPALID
AWAATSSFKSLMQRNTYANDSVNYEYAFTGVAHYQSTTLGYDALIAKSNWTAEYSKWTHLVDILEKFNGQTLFSVDSGWM
WGHNRAFVSAVNTDGSTSAYNGASPQAGALLQATVLQISLSDQQMARLQQSYDALLDSVYGGLVLQTRLDKYVRILQSDH
PADVLAALQAAYDRNPVNGASDAIDLLKYGSAALDKAGVSLAPTLQSMAQDLDSRGLLSTWLADNPGIHYTAPGQAAAIG
KTGELNGLFILTGPTQKADPVQASAGQGSQGNVFFALHGNTTVDASKGDNQQFFGGDGPSRFVGGTGANRFQGGAGDMWM
DGHLGSAGTFTGGKGNDTMIGGTGLNIFSGGGGDDAITSNADAVSLIDGGIGNDTIRVSGGGMASIDGGAGDDIIRIDPY
GASQGADIMGGTGDDQISLGYYSTTLRFNRGDGHDTVSSIANAGNKTIVFGPGISAADLSATRVGNDMVLNVGANGDAIT
ITNWFLLDGSKRIDTAVFADGTRWNADNFRRLITTVTGTAGDDTINGWQGDDVLVGGDGNDTLVSRSANSFAKSAELGED

Sequences:

>Translated_960_residues
MARAYLDTLEKIAEENRKLTGNDEVNRDIQAKEVWDFHREVFQKNGLGVENWTLDSVFKTIQQTQGDDALEAYWESLRDT
QGEGMMATLLNIRTMYNMHESIDSADPAISKLARNWMELVPGIFSSEQFMRSIKVLLRLPDVKSTLNAIDDLVNQLFRSV
QFDSGRDPLVVDLGKGIRATGVDDSKVLFDLANAGQKEAVGWIASGGFLVNTADGPVTSGAQLFGDARALPDGSLAANGF
QALAPLDSNADGHINASDTAFGKLAIWTDTNQDGIEQADEVFLLSKLGIQDIDLTSETSTFQNIGGGNVVTGKAKITWAD
GHQTDIVEANLVTNGFYTVFTDNVTLTPEQAALPFVRGSGQVRDTRQAAARSPDFSAMLQQYAAANTRAEQLALLPALID
AWAATSSFKSLMQRNTYANDSVNYEYAFTGVAHYQSTTLGYDALIAKSNWTAEYSKWTHLVDILEKFNGQTLFSVDSGWM
WGHNRAFVSAVNTDGSTSAYNGASPQAGALLQATVLQISLSDQQMARLQQSYDALLDSVYGGLVLQTRLDKYVRILQSDH
PADVLAALQAAYDRNPVNGASDAIDLLKYGSAALDKAGVSLAPTLQSMAQDLDSRGLLSTWLADNPGIHYTAPGQAAAIG
KTGELNGLFILTGPTQKADPVQASAGQGSQGNVFFALHGNTTVDASKGDNQQFFGGDGPSRFVGGTGANRFQGGAGDMWM
DGHLGSAGTFTGGKGNDTMIGGTGLNIFSGGGGDDAITSNADAVSLIDGGIGNDTIRVSGGGMASIDGGAGDDIIRIDPY
GASQGADIMGGTGDDQISLGYYSTTLRFNRGDGHDTVSSIANAGNKTIVFGPGISAADLSATRVGNDMVLNVGANGDAIT
ITNWFLLDGSKRIDTAVFADGTRWNADNFRRLITTVTGTAGDDTINGWQGDDVLVGGDGNDTLVSRSANSFAKSAELGED
>Mature_959_residues
ARAYLDTLEKIAEENRKLTGNDEVNRDIQAKEVWDFHREVFQKNGLGVENWTLDSVFKTIQQTQGDDALEAYWESLRDTQ
GEGMMATLLNIRTMYNMHESIDSADPAISKLARNWMELVPGIFSSEQFMRSIKVLLRLPDVKSTLNAIDDLVNQLFRSVQ
FDSGRDPLVVDLGKGIRATGVDDSKVLFDLANAGQKEAVGWIASGGFLVNTADGPVTSGAQLFGDARALPDGSLAANGFQ
ALAPLDSNADGHINASDTAFGKLAIWTDTNQDGIEQADEVFLLSKLGIQDIDLTSETSTFQNIGGGNVVTGKAKITWADG
HQTDIVEANLVTNGFYTVFTDNVTLTPEQAALPFVRGSGQVRDTRQAAARSPDFSAMLQQYAAANTRAEQLALLPALIDA
WAATSSFKSLMQRNTYANDSVNYEYAFTGVAHYQSTTLGYDALIAKSNWTAEYSKWTHLVDILEKFNGQTLFSVDSGWMW
GHNRAFVSAVNTDGSTSAYNGASPQAGALLQATVLQISLSDQQMARLQQSYDALLDSVYGGLVLQTRLDKYVRILQSDHP
ADVLAALQAAYDRNPVNGASDAIDLLKYGSAALDKAGVSLAPTLQSMAQDLDSRGLLSTWLADNPGIHYTAPGQAAAIGK
TGELNGLFILTGPTQKADPVQASAGQGSQGNVFFALHGNTTVDASKGDNQQFFGGDGPSRFVGGTGANRFQGGAGDMWMD
GHLGSAGTFTGGKGNDTMIGGTGLNIFSGGGGDDAITSNADAVSLIDGGIGNDTIRVSGGGMASIDGGAGDDIIRIDPYG
ASQGADIMGGTGDDQISLGYYSTTLRFNRGDGHDTVSSIANAGNKTIVFGPGISAADLSATRVGNDMVLNVGANGDAITI
TNWFLLDGSKRIDTAVFADGTRWNADNFRRLITTVTGTAGDDTINGWQGDDVLVGGDGNDTLVSRSANSFAKSAELGED

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 12 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 101639; Mature: 101508

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAYLDTLEKIAEENRKLTGNDEVNRDIQAKEVWDFHREVFQKNGLGVENWTLDSVFKT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IQQTQGDDALEAYWESLRDTQGEGMMATLLNIRTMYNMHESIDSADPAISKLARNWMELV
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PGIFSSEQFMRSIKVLLRLPDVKSTLNAIDDLVNQLFRSVQFDSGRDPLVVDLGKGIRAT
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEC
GVDDSKVLFDLANAGQKEAVGWIASGGFLVNTADGPVTSGAQLFGDARALPDGSLAANGF
CCCCHHHHHHHHCCCCHHHCEEEECCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCC
QALAPLDSNADGHINASDTAFGKLAIWTDTNQDGIEQADEVFLLSKLGIQDIDLTSETST
CEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
FQNIGGGNVVTGKAKITWADGHQTDIVEANLVTNGFYTVFTDNVTLTPEQAALPFVRGSG
HHHCCCCCEEECCEEEEECCCCCCCEEEEEEEECCEEEEEECCEEECCHHHCCCEECCCC
QVRDTRQAAARSPDFSAMLQQYAAANTRAEQLALLPALIDAWAATSSFKSLMQRNTYAND
CCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVNYEYAFTGVAHYQSTTLGYDALIAKSNWTAEYSKWTHLVDILEKFNGQTLFSVDSGWM
CCCEEEEEEEEEHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEE
WGHNRAFVSAVNTDGSTSAYNGASPQAGALLQATVLQISLSDQQMARLQQSYDALLDSVY
ECCCCEEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
GGLVLQTRLDKYVRILQSDHPADVLAALQAAYDRNPVNGASDAIDLLKYGSAALDKAGVS
CCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCC
LAPTLQSMAQDLDSRGLLSTWLADNPGIHYTAPGQAAAIGKTGELNGLFILTGPTQKADP
HHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEECCCCCCCCEEEEEECCCCCCCC
VQASAGQGSQGNVFFALHGNTTVDASKGDNQQFFGGDGPSRFVGGTGANRFQGGAGDMWM
CCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
DGHLGSAGTFTGGKGNDTMIGGTGLNIFSGGGGDDAITSNADAVSLIDGGIGNDTIRVSG
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEC
GGMASIDGGAGDDIIRIDPYGASQGADIMGGTGDDQISLGYYSTTLRFNRGDGHDTVSSI
CCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCHHHHHHH
ANAGNKTIVFGPGISAADLSATRVGNDMVLNVGANGDAITITNWFLLDGSKRIDTAVFAD
HCCCCCEEEECCCCCCCCCHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCCCCEEEEEC
GTRWNADNFRRLITTVTGTAGDDTINGWQGDDVLVGGDGNDTLVSRSANSFAKSAELGED
CCEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEECCHHHHHHHHCCCCC
>Mature Secondary Structure 
ARAYLDTLEKIAEENRKLTGNDEVNRDIQAKEVWDFHREVFQKNGLGVENWTLDSVFKT
CHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IQQTQGDDALEAYWESLRDTQGEGMMATLLNIRTMYNMHESIDSADPAISKLARNWMELV
HHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PGIFSSEQFMRSIKVLLRLPDVKSTLNAIDDLVNQLFRSVQFDSGRDPLVVDLGKGIRAT
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEC
GVDDSKVLFDLANAGQKEAVGWIASGGFLVNTADGPVTSGAQLFGDARALPDGSLAANGF
CCCCHHHHHHHHCCCCHHHCEEEECCCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCC
QALAPLDSNADGHINASDTAFGKLAIWTDTNQDGIEQADEVFLLSKLGIQDIDLTSETST
CEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
FQNIGGGNVVTGKAKITWADGHQTDIVEANLVTNGFYTVFTDNVTLTPEQAALPFVRGSG
HHHCCCCCEEECCEEEEECCCCCCCEEEEEEEECCEEEEEECCEEECCHHHCCCEECCCC
QVRDTRQAAARSPDFSAMLQQYAAANTRAEQLALLPALIDAWAATSSFKSLMQRNTYAND
CCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVNYEYAFTGVAHYQSTTLGYDALIAKSNWTAEYSKWTHLVDILEKFNGQTLFSVDSGWM
CCCEEEEEEEEEHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCEE
WGHNRAFVSAVNTDGSTSAYNGASPQAGALLQATVLQISLSDQQMARLQQSYDALLDSVY
ECCCCEEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHH
GGLVLQTRLDKYVRILQSDHPADVLAALQAAYDRNPVNGASDAIDLLKYGSAALDKAGVS
CCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCC
LAPTLQSMAQDLDSRGLLSTWLADNPGIHYTAPGQAAAIGKTGELNGLFILTGPTQKADP
HHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEECCCCCCCCEEEEEECCCCCCCC
VQASAGQGSQGNVFFALHGNTTVDASKGDNQQFFGGDGPSRFVGGTGANRFQGGAGDMWM
CCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
DGHLGSAGTFTGGKGNDTMIGGTGLNIFSGGGGDDAITSNADAVSLIDGGIGNDTIRVSG
CCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEC
GGMASIDGGAGDDIIRIDPYGASQGADIMGGTGDDQISLGYYSTTLRFNRGDGHDTVSSI
CCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCCHHHHHHH
ANAGNKTIVFGPGISAADLSATRVGNDMVLNVGANGDAITITNWFLLDGSKRIDTAVFAD
HCCCCCEEEECCCCCCCCCHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCCCCEEEEEC
GTRWNADNFRRLITTVTGTAGDDTINGWQGDDVLVGGDGNDTLVSRSANSFAKSAELGED
CCEECHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]