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The map label for this gene is yafC [C]

Identifier: 17544784

GI number: 17544784

Start: 73037

End: 73975

Strand: Direct

Name: yafC [C]

Synonym: RSc0065

Alternate gene names: 17544784

Gene position: 73037-73975 (Clockwise)

Preceding gene: 17544782

Following gene: 17544789

Centisome position: 1.97

GC content: 67.09

Gene sequence:

>939_bases
ATGGATCGCTTGCAGTCGATGCGCGTGTTCTCCAAGGTGGTGGAGCTCGGCAGCTTTGCCCGGGCTGCGCAGCATCTGTC
GATGTCCAATGCCGTGGTCACCCGCTACGTGGCCGACCTGGAGGCCCATCTCGGCACGCGCCTGCTCAACCGCACCACGC
GCAGCCTGTCGTTGACGGACGTGGGCGAGACCTATCTGCAGCGCTGTCAGCAGATCCTGCTGGACATCGATGAAGCCGAA
TCGCTTGCCACATCGCGCAGCCAGGCGCTGGTCGGCAGCCTGCGCATCGTCGCGCCGGTCATGTTCGGGCTGCACGTGCT
GCCGATGCTGCTGGCGCGCTTCCAGCAGCTCTATCCTGAGGTGACCTTCGACGTGGCACTGTCGGACCGTCCGATCGATA
TCGTCGAGGATGGGCGCGACGTCGGCATCATGGTGTCGGAACTCGGCCTGGGCTCGCACCTCGTGGCGCGCCGGATGATC
TCTGCCGAGATGGTCATGGCGGCCACCCCCGCCTACCTGCGCCAGCACTCCACGCCGCAGCGCGCCGAAGACATCGCCGA
CCACCGCGTGATCGCCATGTGGCATCCGCAACTGCGGCACGAGTGGGAGATGACTGCGCCGGACGGCCAGTCGATCGCGG
TGCCGGTGCAGCCGTCGCTGGTGACCAGCAACGCCGAGCTGATGCACCGCGCGGTGCTGGCCGACATGGGGATCGCCATC
CTGTCGTCTTACATGGCGCGGCCGGATCTGGAGTCGGGGCGGCTGGTGCGCGTGCTGCCGCAGTACAAGCTGCCGCACCG
ATCGCTATCGCTGGTCTACCCGAGCCGCAAGTTCCTGCCGACCAAGGTGCGCACCTTCATCGACTACATGTTGGCCCAGG
CGATGGAGGCCAAGCAGAGCGAGGCCCGCGCCGGCCGCGCGCTGACCGAGGCCGCATAA

Upstream 100 bases:

>100_bases
ATGCGCCATTCCGCGCGATAAATTGCTTGGTCCAATACCAAAATTTGAAGTCGAAAAAGATTTGCTCTATTTTTGACAAC
AAATCATGTGAGAGGCCGGA

Downstream 100 bases:

>100_bases
GCGCGCAGCCGGCCGATTCAGGCGGCGCCCAAAGCAGAACGGGAGGCACACTGTCCTCCCGTTTTTTTTGCATCGATGCC
GGCCCGGCCGACGGCCAAGG

Product: transcription regulator protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDRLQSMRVFSKVVELGSFARAAQHLSMSNAVVTRYVADLEAHLGTRLLNRTTRSLSLTDVGETYLQRCQQILLDIDEAE
SLATSRSQALVGSLRIVAPVMFGLHVLPMLLARFQQLYPEVTFDVALSDRPIDIVEDGRDVGIMVSELGLGSHLVARRMI
SAEMVMAATPAYLRQHSTPQRAEDIADHRVIAMWHPQLRHEWEMTAPDGQSIAVPVQPSLVTSNAELMHRAVLADMGIAI
LSSYMARPDLESGRLVRVLPQYKLPHRSLSLVYPSRKFLPTKVRTFIDYMLAQAMEAKQSEARAGRALTEAA

Sequences:

>Translated_312_residues
MDRLQSMRVFSKVVELGSFARAAQHLSMSNAVVTRYVADLEAHLGTRLLNRTTRSLSLTDVGETYLQRCQQILLDIDEAE
SLATSRSQALVGSLRIVAPVMFGLHVLPMLLARFQQLYPEVTFDVALSDRPIDIVEDGRDVGIMVSELGLGSHLVARRMI
SAEMVMAATPAYLRQHSTPQRAEDIADHRVIAMWHPQLRHEWEMTAPDGQSIAVPVQPSLVTSNAELMHRAVLADMGIAI
LSSYMARPDLESGRLVRVLPQYKLPHRSLSLVYPSRKFLPTKVRTFIDYMLAQAMEAKQSEARAGRALTEAA
>Mature_312_residues
MDRLQSMRVFSKVVELGSFARAAQHLSMSNAVVTRYVADLEAHLGTRLLNRTTRSLSLTDVGETYLQRCQQILLDIDEAE
SLATSRSQALVGSLRIVAPVMFGLHVLPMLLARFQQLYPEVTFDVALSDRPIDIVEDGRDVGIMVSELGLGSHLVARRMI
SAEMVMAATPAYLRQHSTPQRAEDIADHRVIAMWHPQLRHEWEMTAPDGQSIAVPVQPSLVTSNAELMHRAVLADMGIAI
LSSYMARPDLESGRLVRVLPQYKLPHRSLSLVYPSRKFLPTKVRTFIDYMLAQAMEAKQSEARAGRALTEAA

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=35.5400696864112, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=34.2465753424658, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=32.2916666666667, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=29.6551724137931, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.7123287671233, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=28.7625418060201, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789173, Length=300, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=25.2595155709343, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788481, Length=307, Percent_Identity=25.4071661237785, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=31.4285714285714, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=25.6, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=119, Percent_Identity=27.7310924369748, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787879, Length=148, Percent_Identity=31.7567567567568, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34771; Mature: 34771

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLQSMRVFSKVVELGSFARAAQHLSMSNAVVTRYVADLEAHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGETYLQRCQQILLDIDEAESLATSRSQALVGSLRIVAPVMFGLHVLPMLLARFQQLYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTFDVALSDRPIDIVEDGRDVGIMVSELGLGSHLVARRMISAEMVMAATPAYLRQHSTPQ
CEEEEEECCCCCHHHCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
RAEDIADHRVIAMWHPQLRHEWEMTAPDGQSIAVPVQPSLVTSNAELMHRAVLADMGIAI
HHHHHHCCCEEEEECHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LSSYMARPDLESGRLVRVLPQYKLPHRSLSLVYPSRKFLPTKVRTFIDYMLAQAMEAKQS
HHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EARAGRALTEAA
HHHHCCHHHCCC
>Mature Secondary Structure
MDRLQSMRVFSKVVELGSFARAAQHLSMSNAVVTRYVADLEAHLGTRLLNRTTRSLSLTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VGETYLQRCQQILLDIDEAESLATSRSQALVGSLRIVAPVMFGLHVLPMLLARFQQLYPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTFDVALSDRPIDIVEDGRDVGIMVSELGLGSHLVARRMISAEMVMAATPAYLRQHSTPQ
CEEEEEECCCCCHHHCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
RAEDIADHRVIAMWHPQLRHEWEMTAPDGQSIAVPVQPSLVTSNAELMHRAVLADMGIAI
HHHHHHCCCEEEEECHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
LSSYMARPDLESGRLVRVLPQYKLPHRSLSLVYPSRKFLPTKVRTFIDYMLAQAMEAKQS
HHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EARAGRALTEAA
HHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]