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The map label for this gene is mreB [H]

Identifier: 17544778

GI number: 17544778

Start: 64477

End: 65520

Strand: Direct

Name: mreB [H]

Synonym: RSc0059

Alternate gene names: 17544778

Gene position: 64477-65520 (Clockwise)

Preceding gene: 17544760

Following gene: 17544779

Centisome position: 1.73

GC content: 66.09

Gene sequence:

>1044_bases
ATGTTCGGCTTTCTGCGCAGCTATTTTTCCAACGATCTCGCGATCGACCTCGGCACCGCCAACACCCTGATCTACGTCCG
CGACAAGGGCATCGTCCTCGACGAACCGTCCGTGGTCGCCATTCGCCAGGAAGGCGGCCCGAACGCCAAGAAGACCATCC
AGGCCGTCGGCAAGGAAGCCAAGCAGATGCTGGGCAAGGTGCCGGGCAACATCGAGGCGATCCGCCCGATGAAGGACGGC
GTGATCGCCGACTTCACCGTCACCGAGCAGATGCTCAAGCAGTTCATCAAGATGGTGCACGACAGCAAGCTGCTGCGCCC
GTCGCCGCGCATCATCATCTGCGTGCCGTGCGGCTCGACCCAGGTGGAGCGTCGCGCCATCCGCGAATCGGCGCTGGGCG
CCGGCGCCTCGCAGGTGTACCTGATCGAGGAGCCGATGGCGGCCGCGATCGGCGCCGGCCTGCCGGTGTCGGAGCCGTCG
GGCTCGATGGTGGTGGACATCGGCGGCGGCACCACCGAGGTGGGCATCATCTCGCTGGGCGGCATGGTCTACAAGGGTTC
GGTGCGCGTGGGCGGCGACAAGTTCGACGAGGCCATCGTCAACTACATCCGCCGCAACTACGGCATGCTGATCGGCGAGC
AGACCGCCGAAGCCATCAAGAAGGAAATCGGCTCCGCCTTCCCGGGTTCGGAAGTGCGCGAGATGGAGGTCAAGGGCCGC
AACCTGTCCGAGGGCATTCCGCGTGCCTTCACGGTGTCGTCCAACGAAATCCTGGAAGCGCTGACCGATCCGCTCAACCA
GATCGTGTCGTCGGTCAAGATCGCGCTCGAGCAGACGCCGCCGGAACTGGGCGCCGACATCGCCGAGCGCGGCATGATGC
TGACCGGCGGCGGCGCGCTGCTGCGCGACCTGGATCGCCTGCTGGCCGAGGAAACCGGCCTGCCGGTGCTGGTGGCCGAA
GATCCGCTGACCTGCGTGGTGCGCGGCTCCGGCATGGCGCTGGAGCGCATGGACAAGCTCGGCAGCATCTTCTCGTACGA
GTGA

Upstream 100 bases:

>100_bases
CCGCATGGCAGCGCCAGGCGACGTCCGCGCATCGGTGCAGCCGTTGCACCGTGATTCTGCGATTGGGCGTCCCATGACTT
GAGAAAACAGGATTCATCCG

Downstream 100 bases:

>100_bases
TGCGCCACCGTTTGCCATCCGTTCATGTGGCCGCGCAGGCGGCCTGGGCGGATCGCTGACATGCGCACTGTGCCGGTGCG
ACGTGCTCCGCCCTCCCCGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Sequences:

>Translated_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE
>Mature_347_residues
MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEAKQMLGKVPGNIEAIRPMKDG
VIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGSTQVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPS
GSMVVDIGGGTTEVGIISLGGMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGALLRDLDRLLAEETGLPVLVAE
DPLTCVVRGSGMALERMDKLGSIFSYE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=350, Percent_Identity=72.2857142857143, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1788875, Length=247, Percent_Identity=27.1255060728745, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323401, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37086; Mature: 37086

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
QVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPSGSMVVDIGGGTTEVGIISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFGFLRSYFSNDLAIDLGTANTLIYVRDKGIVLDEPSVVAIRQEGGPNAKKTIQAVGKEA
CCHHHHHHCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHH
KQMLGKVPGNIEAIRPMKDGVIADFTVTEQMLKQFIKMVHDSKLLRPSPRIIICVPCGST
HHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
QVERRAIRESALGAGASQVYLIEEPMAAAIGAGLPVSEPSGSMVVDIGGGTTEVGIISLG
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEQTAEAIKKEIGSAFPGSEVREMEVKGR
CEEEECCEEECCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHCCCCCCCCHHHHHHCCC
NLSEGIPRAFTVSSNEILEALTDPLNQIVSSVKIALEQTPPELGADIAERGMMLTGGGAL
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCEEEECCHHH
LRDLDRLLAEETGLPVLVAEDPLTCVVRGSGMALERMDKLGSIFSYE
HHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]