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The map label for this gene is regB [H]

Identifier: 17544758

GI number: 17544758

Start: 41881

End: 43227

Strand: Direct

Name: regB [H]

Synonym: RSc0039

Alternate gene names: 17544758

Gene position: 41881-43227 (Clockwise)

Preceding gene: 17544755

Following gene: 17544759

Centisome position: 1.13

GC content: 71.34

Gene sequence:

>1347_bases
ATGCTCTCTACCCTGCCGCTCGCCGCTCCACCGCTCGACACGTCCAGTCTACGCCGCCTGTTCTGGCTGCGATGGAGCCT
GCTGGCCACGCAGCTGATCCTGATGCTGCTGGCGCCGCTCATCTTCGGCGTGCAGCTGCCGGTGGCGGTGCTGCTGAGCG
TGATGGGCGTGCACGCGCTGTTCAACCTGCTGACCGGCTGGCAAGTGCGGCGCGACCGCCCGGTGCGGCACATCGAGATC
ACCGTCCAGCTGCTGGTGGATCTGACCGCGCTGTCCGCGCTGCTGTATTTCACGGGCGGCGCGACCAACCCCTTCGTGTC
GTTCTATCTGCCTGCGCTGGCGATCGCCGCGGCCATGCTGCCGATCGCGCATGTGGTGGGGCTGACGCTGTACGCGCTGG
CGGCCTACAGCGTGATGCTGGGCAACTACATTCCGCTGGATCTGCTGGACCAGGCGGATGCGGTGCCTTATCACCTCGCC
GGCATGTGGATCGACTTCGTCGCCAGCAGCGCCATGATCGCCGGGTTCACCGCGCGGCTGTCGGCGGCGCTGCGCGAGCG
CGAAGCCGAACTCGCCGACGCGCGCGAGCGCCTGCTGCGCGAGCAGCGCATCGAGGCGCTGGTGTCGCAGGGCGCCAGCG
TGGCGCACGAGATGGGCACGCCGCTGTCCACCGTGGCCGTCATCACCGGCGAGCTGCAGCACGACGCCCGCCAGCCCGAT
TCGCCGCTGGCGCCTTACCGCGAAGACCTGCGCGCCATCGAGCAGCAGCTGGAGCTGTGCCGCGCCGCGCTGGCGCGCCT
GCAGCGCAAGCCGAACGACGGCACGCCCGAGCCGCTCGGCCTGTGGCTGCCGGCCTTCACGCAGACGTGGCAGCTGCGCC
ATCCGGACATCCGCCTGCACACCGAGAGCTCGCCGGCTGCGCAGGCGGTGGAACTGGACGCGGTCGTTGTCGGCCAGATC
CTCACCATCCTGCTCGACAACGCGGCGCGCAGCCAGCAGCAGGCCGGGCGCGATCAGGTGCCGCTGCTGCTGACCGCCAG
GATCGATGCCAACGCGGACACCGTGCGCGAGGCGCCCCGGCAGATCGTGCTGTCGGTGGTCGATACCGGCCTGGGCGTGC
CGGACGACCTGCGCACCGCGCTCGGCCGCACGCCCGTGCCGAGCCGCCACGGCGGCCATGGCATCGGCCTCTACCTGGCG
GCGACCACGGCGCGCCGGCTGGGCGGCACCGTCGAGCTGCGTTCCAACCCGCCGCAGGGCGCGATCGCAGAACTGCGGCT
GCCCGCGGCGGGTCCTAATGCACAACCGGCCGCACCCGCCATCGGTGCGCCGACCCTGTTGACCTGA

Upstream 100 bases:

>100_bases
CAGCGCTGATCGCGTGGGGCGTTGGGTGCACAATTGTGCGTCTGATTGACGCATGACGTGGCCAGAACTTGCGTGCTGGC
GGCGTTTACACTTGTTCTCC

Downstream 100 bases:

>100_bases
TTGACGATCTGATGAGGCCGCGGTCAGCGCGGTCCGGAGAAACACCATGCAGCAACCCGCCCCCTTCCTGATCCTCGACG
ACGATGACGTGTTCGCGCAG

Product: transmembrane sensor histidine kinase transcription regulator protein

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLSTLPLAAPPLDTSSLRRLFWLRWSLLATQLILMLLAPLIFGVQLPVAVLLSVMGVHALFNLLTGWQVRRDRPVRHIEI
TVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAMLPIAHVVGLTLYALAAYSVMLGNYIPLDLLDQADAVPYHLA
GMWIDFVASSAMIAGFTARLSAALREREAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPD
SPLAPYREDLRAIEQQLELCRAALARLQRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLHTESSPAAQAVELDAVVVGQI
LTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPRQIVLSVVDTGLGVPDDLRTALGRTPVPSRHGGHGIGLYLA
ATTARRLGGTVELRSNPPQGAIAELRLPAAGPNAQPAAPAIGAPTLLT

Sequences:

>Translated_448_residues
MLSTLPLAAPPLDTSSLRRLFWLRWSLLATQLILMLLAPLIFGVQLPVAVLLSVMGVHALFNLLTGWQVRRDRPVRHIEI
TVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAMLPIAHVVGLTLYALAAYSVMLGNYIPLDLLDQADAVPYHLA
GMWIDFVASSAMIAGFTARLSAALREREAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPD
SPLAPYREDLRAIEQQLELCRAALARLQRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLHTESSPAAQAVELDAVVVGQI
LTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPRQIVLSVVDTGLGVPDDLRTALGRTPVPSRHGGHGIGLYLA
ATTARRLGGTVELRSNPPQGAIAELRLPAAGPNAQPAAPAIGAPTLLT
>Mature_448_residues
MLSTLPLAAPPLDTSSLRRLFWLRWSLLATQLILMLLAPLIFGVQLPVAVLLSVMGVHALFNLLTGWQVRRDRPVRHIEI
TVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAMLPIAHVVGLTLYALAAYSVMLGNYIPLDLLDQADAVPYHLA
GMWIDFVASSAMIAGFTARLSAALREREAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPD
SPLAPYREDLRAIEQQLELCRAALARLQRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLHTESSPAAQAVELDAVVVGQI
LTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPRQIVLSVVDTGLGVPDDLRTALGRTPVPSRHGGHGIGLYLA
ATTARRLGGTVELRSNPPQGAIAELRLPAAGPNAQPAAPAIGAPTLLT

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786837, Length=133, Percent_Identity=33.8345864661654, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48235; Mature: 48235

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTLPLAAPPLDTSSLRRLFWLRWSLLATQLILMLLAPLIFGVQLPVAVLLSVMGVHAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNLLTGWQVRRDRPVRHIEITVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAML
HHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
PIAHVVGLTLYALAAYSVMLGNYIPLDLLDQADAVPYHLAGMWIDFVASSAMIAGFTARL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAALREREAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SPLAPYREDLRAIEQQLELCRAALARLQRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHCCCCCCCCCEEEE
TESSPAAQAVELDAVVVGQILTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHH
QIVLSVVDTGLGVPDDLRTALGRTPVPSRHGGHGIGLYLAATTARRLGGTVELRSNPPQG
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHCCCEEEECCCCCCC
AIAELRLPAAGPNAQPAAPAIGAPTLLT
CHHEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSTLPLAAPPLDTSSLRRLFWLRWSLLATQLILMLLAPLIFGVQLPVAVLLSVMGVHAL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNLLTGWQVRRDRPVRHIEITVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAML
HHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
PIAHVVGLTLYALAAYSVMLGNYIPLDLLDQADAVPYHLAGMWIDFVASSAMIAGFTARL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAALREREAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SPLAPYREDLRAIEQQLELCRAALARLQRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHHCCCCCCCCCEEEE
TESSPAAQAVELDAVVVGQILTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHH
QIVLSVVDTGLGVPDDLRTALGRTPVPSRHGGHGIGLYLAATTARRLGGTVELRSNPPQG
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHCCCEEEECCCCCCC
AIAELRLPAAGPNAQPAAPAIGAPTLLT
CHHEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]