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The map label for this gene is gap2 [H]

Identifier: 17232554

GI number: 17232554

Start: 6034535

End: 6035548

Strand: Reverse

Name: gap2 [H]

Synonym: all5062

Alternate gene names: 17232554

Gene position: 6035548-6034535 (Counterclockwise)

Preceding gene: 17232555

Following gene: 17232552

Centisome position: 94.1

GC content: 46.35

Gene sequence:

>1014_bases
GTGATTAGAGTCGCAATCAACGGTTTCGGTCGTATTGGGCGTAACTTTGCACGCTGCTGGCTGGGACGAGAAAATACTAA
TATTGAGCTTGTAGCTGTTAACGACACATCAGATCCGAGGACTAATGCTCACCTCCTGAAGTATGACTCAATGCTTGGGA
AGTTAAAGAATGTTGACATTACGGCTGATGATAACTCTATCACCGTTAACGGTAAGACCATTAAATGCGTATCTGATCGC
AATCCAGAAAACTTGCCCTGGAAGGAATGGGAGATTGACTTAATTATCGAAGCAACGGGCGTATTTGTAAGCAAAGAAGG
TGCGACAAAGCACATTAATGCTGGAGCGAAGAAGGTTCTGATCACTGCCCCCGGTAAAAACGAGGATGGTACCTTCGTAA
TGGGTGTAAATCATCACGACTACGATCACAACCTACACAACATTATCAGTAATGCCAGCTGTACAACTAACTGTCTAGCT
CCCATCGCCAAGGTACTGAACGACAAATTCGGGATCATCAAAGGCAGCATGACAACCACCCACAGCTACACAGGTGATCA
GCGCTTATTAGATGCTTCTCACCGTGATTTACGCAGGGCAAGGGCCGCCGCTATCAATATCGTCCCTACCTCCACCGGTG
CGGCGAAAGCAGTGGCTCTAGTGATCCCAGAACTAAAAGGCAAGCTTAATGGCGTTGCCTTGCGCGTACCTACCCCGAAC
GTCTCAATGGTAGATTTCGTAGTTCAGGTTGAGAAGCGTACTATTACTGAAGAAGTCAACCAAGCCCTCAAAGATGCGTC
TGAAGGCCCACTGAAAGGAATTTTGGACTACAGCGAACTGCAATTGGTATCGTCCGATTATCAAGGAACTGATGCTTCCT
CTATCGTTGATGCTAACTTGACCCTAGTTATGGGTAATGATCTTGTGAAAGTTATGGCTTGGTATGACAACGAATGGGGT
TACAGCCAACGCGTTCTCGACTTGGCAGAATTAGTAGCCGAAAAATGGGTTTAA

Upstream 100 bases:

>100_bases
TGGATCTGACACTTTATGGTTATAAATACCCTCCCCCTTTGCGATATGATTGGGGTCAAAGATATCAACTTATAGGCATA
TATACAGAGGGCAAGATACT

Downstream 100 bases:

>100_bases
GTTAGCTTTGTAAATTGTTAGTTGTCAGTAGTGTTTAGCATTATTAACCAGTGACAACTAGCAATTGATCCTAGTGACCA
AAATGTTGAAATCCCTGACT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDR
NPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVLITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLA
PIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPN
VSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANLTLVMGNDLVKVMAWYDNEWG
YSQRVLDLAELVAEKWV

Sequences:

>Translated_337_residues
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDR
NPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVLITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLA
PIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPN
VSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANLTLVMGNDLVKVMAWYDNEWG
YSQRVLDLAELVAEKWV
>Mature_337_residues
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDITADDNSITVNGKTIKCVSDR
NPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVLITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLA
PIAKVLNDKFGIIKGSMTTTHSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPN
VSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANLTLVMGNDLVKVMAWYDNEWG
YSQRVLDLAELVAEKWV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=46.1309523809524, Blast_Score=301, Evalue=4e-82,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=45.5927051671732, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=50, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=44.0729483282675, Blast_Score=282, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17534677, Length=341, Percent_Identity=46.9208211143695, Blast_Score=299, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=341, Percent_Identity=46.9208211143695, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=47.2140762463343, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=47.2140762463343, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321631, Length=338, Percent_Identity=52.0710059171598, Blast_Score=330, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=51.0324483775811, Blast_Score=329, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6322468, Length=338, Percent_Identity=51.7751479289941, Blast_Score=328, Evalue=1e-90,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=44.5103857566766, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=44.5103857566766, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=44.8071216617211, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=44.8071216617211, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI19922412, Length=337, Percent_Identity=44.5103857566766, Blast_Score=283, Evalue=1e-76,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36910; Mature: 36910

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDI
CEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCEE
TADDNSITVNGKTIKCVSDRNPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVL
EECCCEEEECCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCEECCCCCEEE
ITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLAPIAKVLNDKFGIIKGSMTTT
EECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEC
HSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPN
CCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHEEEEEEHHHCCCCCCEEEEECCCC
VSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANL
CHHHHHEEHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHEEEECCCCCCCCCCEEECEE
TLVMGNDLVKVMAWYDNEWGYSQRVLDLAELVAEKWV
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRVAINGFGRIGRNFARCWLGRENTNIELVAVNDTSDPRTNAHLLKYDSMLGKLKNVDI
CEEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCEE
TADDNSITVNGKTIKCVSDRNPENLPWKEWEIDLIIEATGVFVSKEGATKHINAGAKKVL
EECCCEEEECCCEEEEECCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCEECCCCCEEE
ITAPGKNEDGTFVMGVNHHDYDHNLHNIISNASCTTNCLAPIAKVLNDKFGIIKGSMTTT
EECCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEC
HSYTGDQRLLDASHRDLRRARAAAINIVPTSTGAAKAVALVIPELKGKLNGVALRVPTPN
CCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHEEEEEEHHHCCCCCCEEEEECCCC
VSMVDFVVQVEKRTITEEVNQALKDASEGPLKGILDYSELQLVSSDYQGTDASSIVDANL
CHHHHHEEHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHEEEECCCCCCCCCCEEECEE
TLVMGNDLVKVMAWYDNEWGYSQRVLDLAELVAEKWV
EEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]